Research advancement of the key properties and applications of machinable polymer-infiltrated-ceramicnetwork（PICN）composites for dental restorations

doi:10.3877/cma.j.issn.1674-1366.2025.02.008

Abstract

Abstract:

Polymer-infiltrated-ceramic-network（PICN）composites have been given increasing attention as dental restorative materials due to the excellent combination of the mechanical compatibility with natural teeth，the lifelike aesthetic property stemmed from ceramics and the good machinability ascribed to the resin.This article presents a stateof-the -art review on PICN composites regarding their key properties，such as mechanical properties，aesthetic properties，biocompatibility and adhesive properties，as well as the changes of the above properties under different environment conditions，and finally provides an outlook for their future development trend.The main purpose of this article was to provide valuable instructions for researchers to further optimize the design of material properties，and also to offer a basis for dentists to reasonably select and use PICN composites according to patients′ personal preferences and practical use scenarios in clinical applications.

Key words: Dental material, Polymer-infiltratedceramic-network, Mechanical property, Aesthetic property, Biocompatibility, Adhesive property

Yuxin Hu, Guangchao Lyu, Xiao Ma, Shanshan Cao, Qiulan Li, Ke Zhao, Xinping Zhang. Research advancement of the key properties and applications of machinable polymer-infiltrated-ceramicnetwork（PICN）composites for dental restorations[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2025, 19(02): 132-138.

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References 62

［1］	Eldafrawy M，Nguyen JF，Mainjot AK，et al.A functionally graded PICN material for biomimetic CAD-CAM blocks［J］.J Dent Res，2018，97（12）：1324-1330.DOI：10.1177/002203451 8785364.
［2］	Bona AD，Corazza PH，Zhang Y.Characterization of a polymerinfiltrated ceramic-network material［J］.Dent Mater，2014，30（5）：564-569.DOI：10.1016/j.dental.2014.02.019.
［3］	Coldea A，Swain MV，Thiel N. In vitro strength degradation of dental ceramics and novel PICN material by sharp indentation［J］.J Mech Behav Biomed Mater，2013，26：34-42.DOI：10.1016/j.jmbbm.2013.05.004.
［4］	Hodásová L，Morena AG，Tzanov T，et al.3D-printed polymerinfiltrated ceramic network with antibacterial biobased silver nanoparticles［J］.ACS Appl Bio Mater，2022，5（10）：4803-4813.DOI：10.1021/acsabm.2c00509.
［5］	何三纲.口腔解剖生理学［M］.8 版.北京：人民卫生出版社，2020：244-245.
［6］	Goujat A，Abouelleil H，Colon P，et al.Mechanical properties and internal fit of 4 CAD-CAM block materials［J］.J Prosthet Dent，2018，119（3）：384-389.DOI：10.1016/j.prosdent.2017.03.001.
［7］	Argyrou R，Thompson GA，Cho SH，et al.Edge chipping resistance and flexural strength of polymer infiltrated ceramic network and resin nanoceramic restorative materials ［J］.J Prosthet Dent，2016，116（3）：397-403.DOI：10.1016/j.prosdent.2016.02.014.
［8］	郑梓婷，闫文娟.椅旁CAD/CAM 可切削材料相关性能的研究进展［J］.口腔材料器械杂志，2019，28（3）：46-51.DOI：10.11752/j.kqcl.2019.03.09.
［9］	孙瑞瞳，李享宜，胡一淳，等.硅基陶瓷的临床应用现状与展望［J/OL］.中华口腔医学研究杂志（电子版），2021，15（2）：72-78.DOI：10.3877/cma.j.issn.1674-1366.2021.02.002.
［10］	Ikemoto S，Nagamatsu Y，Masaki C，et al.Development of zirconia-based polymer-infiltrated ceramic network for dental restorative material［J］.J Mech Behav Biomed Mater，2024，150：106320.DOI：10.1016/j.jmbbm.2023.106320.
［11］	Li WY，Sun J.Effects of ceramic density and sintering temperature on the mechanical properties of a novel polymerinfiltrated ceramic-network zirconia dental restorative（filling）material［J］.Med Sci Monitor，2018，24：3068-3076.DOI：10.12659/MSM.907097.
［12］	Ikeda H，Nagamatsu Y，Shimizu H.Preparation of silica-poly（methyl methacrylate）composite with a nanoscale dual-network structure and hardness comparable to human enamel［J］.Dent Mater，2019，35（6）：893-899.DOI：10.1016/j.dental.2019.03.006.
［13］	Maryamnegari SM，Nateghi MR，Mohebat R.Effect of sintering and infiltration conditions on nanoscale dual network SiO₂/polymethyl metacrylate composites mimicking human enamel［J］.J Dent，2022，126：104311.DOI：10.1016/j.jdent.2022.104311.
［14］	胡雨欣，吕广超，马骁，等.牙科树脂渗透陶瓷复合材料制备的研究进展［J］.国际口腔医学杂志，2025，52（1）：133-140.DOI：10.7518/gjkq.2025012.
［15］	Peskersoy C，Sahan HM.Finite element analysis and nanomechanical properties of composite and ceramic dental onlays［J］.Comput Methods Biomech Biomed Engin，2022，25（14）：1649-1661.DOI：10.1080/10255842.2022.2032004.
［16］	Jansen JU，Lümkemann N，Sener B，et al.Comparison of fracture toughness measurements for zirconia materials using two test methods［J］.Dent Mater J，2019，38（5）：806-812.DOI：10.4012/dmj.2018-361.
［17］	Maleki M，Sheikh-Al-Eslamian SM，Hasani E，et al.Comparative study on the microstructure and mechanical behavior of monolithic ceramic and laminated composite of high strength 3YTZP and high fracture toughness 12Ce-TZP［J］.J Alloy Compd，2019，776：166-171.DOI：10.1016/j.jallcom.2018.10.255.
［18］	Zang ST，He NX，Sun XT，et al.Influence of additives on the purity of tetragonal phase and grain size of ceria - stabilized tetragonal zirconia polycrystals（Ce-TZP）［J］.Ceram Int，2019，45：394-400.DOI：10.1016/j.ceramint.2018.09.179.
［19］	Shahmiri R，Standard OC，Hart JN，et al.Optical properties of zirconia ceramics for esthetic dental restorations：A systematic review［J］.J Prosthet Dent，2018，119（1）：36-46.DOI：10.1016/j.prosdent.2017.07.009.
［20］	Mohammed NY，Wahsh MM，Motawea IT，et al.Fabrication and characterization of polymer-infiltrated ceramic network materials based on nano-tetragonal zirconia［J］.J Korean Ceram Soc，2021，58：359-372.DOI：10.1007/s43207-020-00102-4.
［21］	Zhawi HE，Kaizer MR，Chughtai A，et al.Polymer infiltrated ceramic network structures for resistance to fatigue fracture and wear［J］.Dent Mater，2016，32（11）：1352-1361.DOI：10.1016/j.dental.2016.08.216.
［22］	Oudkerk J，Sanchez C，Grenade C，et al.The One-step No-prep technique for non-invasive full-mouth rehabilitation of worn dentition using PICN CAD-CAM restorations：Up to 9-year results from a prospective and retrospective clinical study［J］.Dent Mater，2025，41（4）：414-424.DOI：10.1016/j.dental.2024.12.016.
［23］	Song XF，Kang N，Yin L.Effect of bur selection on machining damage mechanisms of polymer infiltrated ceramic network material for CAD/CAM dental restorations［J］.Ceram Int，2020，46（14）：23116-23126.DOI：10.1016/j.ceramint.2020.06.089.
［24］	Tokunaga J，Ikeda H，Nagamatsu Y，et al.Castable polymerinfiltrated ceramic network composite for training model tooth with compatible machinability to human enamel［J］.Dent Mater J，2022，41（4）：520-526.DOI：10.4012/dmj.2021-299.
［25］	Tokunaga J，Ikeda H，Nagamatsu Y，et al.Wear of polymerinfiltrated ceramic network materials against enamel ［J］.Materials，2022，15（7）：1-13.DOI：10.3390/ma15072435.
［26］	Alves MFRP，de Campos LQB，Simba BG，et al.Microstructural characteristics of 3Y - TZP ceramics and their effects on the flexural strength［J］.Ceramics，2022，5（4）：798-813.DOI：10.3390/ceramics5040058.
［27］	Wille S，Möller R，Kern M.Influence of shading on zirconia′s phase transformation and flexural strength after artificial aging［J］.Dent Mater，2023，39（8）：702-707.DOI：10.1016/j.dental.2023.06.005.
［28］	Gautam C，Joyner J，Gautam A，et al.Zirconia based dental ceramics：Structure，mechanical properties，biocompatibility and applications［J］.Dalton T，2016，45（48）：19194-19215.DOI：10.1039/c6dt03484e.
［29］	Li K，Kou HM，Rao JC，et al.Fabrication of enamel-like structure on polymer-infiltrated zirconia ceramics［J］.Dent Mater，2021，37（4）：e245-e255.DOI：10.1016/j.dental.2021.01.002.
［30］	Shirani M，Savabi O，Mosharraf R，et al.Comparison of translucency and opalescence among different dental monolithic ceramics［J］.J Prosthet Dent，2021，126（3）：446.e1-446.e6.DOI：10.1016/j.prosdent.2021.04.030.
［31］	Ruiz-López J，Espinar C，Lucena C，et al.Effect of thickness on color and translucency of a multi-color polymer-infiltrated ceramicnetwork material［J］.J Esthet Restor Dent，2023，35（2）：381-389.DOI：10.1111/jerd.12952.
［32］	Emamia N，Sjödahl M，Söderholm KM.How filler properties，filler fraction，sample thickness and light source affect light attenuation in particulate filled resin composites ［J］.Dent Mater，2005，21（8）：721-730.DOI：10.1016/j.dental.2005.01.002.
［33］	Pulgar R，Lucena C，Espinar C，et al.Optical and colorimetric evaluation of a multi-color polymer-infiltrated ceramic-network material［J］.Dent Mater，2019，35（7）：e131-e139.DOI：10.1016/j.dental.2019.03.010.
［34］	Amri MD，Labban N，Alhijji S，et al. In vitro evaluation of translucency and color stability of CAD/CAM polymer-infiltrated ceramic materials after accelerated aging［J］.J Prosthodont，2021，30（4）：318-328.DOI：10.1111/jopr.13239.
［35］	Sulaiman TA，Suliman AA，Mohamed EA，et al.Optical properties of bisacryl-，composite-，ceramic- resin restorative materials：An aging simulation study［J］.J Esthet Restor Dent，2021，33（6）：913-918.DOI：10.1111/jerd.12653.
［36］	Acar O，Yilmaz B，Altintas SH，et al.Color stainability of CAD/CAM and nanocomposite resin materials［J］.J Prosthet Dent，2016，115（1）：71-75.DOI：10.1016/j.prosdent.2015.06.014.
［37］	Dos Santos DM，da Silva EVF，Watanabe D，et al.Effect of different acidic solutions on the optical behavior of lithium disilicate ceramics［J］.J Prosthet，2017，118（3）：430-436.DOI：10.1016/j.prosdent.2016.10.023.
［38］	Sen N，Us YO.Mechanical and optical properties of monolithic CAD-CAM restorative materials［J］.J Prosthet Dent，2018，119（4）：593-599.DOI：10.1016/j.prosdent.2017.06.012.
［39］	Lee JH，Kim SH，Yoon HI，et al.Colour stability and surface properties of high-translucency restorative materials for digital dentistry after simulated oral rinsing［J］.Eur J Oral Sci，2020，128（2）：170-180.DOI：10.1111/eos.12676.
［40］	Kilinc H，Turgut S.Optical behaviors of esthetic CAD-CAM restorations after different surface finishing and polishing procedures and UV aging：An in vitro study［J］.J Prosthet Dent，2018，120（1）：107-113.DOI：10.1016/j.prosdent.2017.09.019.
［41］	Choi YS，Kang KH，Att W.Evaluation of the response of esthetic restorative materials to ultraviolet aging［J］.J Prosthet Dent，2021，126（5）：679-685.DOI：10.1016/j.prosdent.2020.09.007.
［42］	Tassin M，Bonte E，Loison-Robert LS，et al.Effects of hightemperature - pressure polymerized resin - infiltrated ceramic networks on oral stem cells［J］.Plos One，2016，11（5）：e0155450.DOI：10.1371/journal.pone.0155450.
［43］	Pomès B，Behin P，Jordan L，et al.Influence of polymerization pressure and post - cure treatment on conversion degree and viscoelastic properties of polymer infiltrated ceramic network［J］.J Mech Behav of Biomed，2021，115：104286.DOI：10.1016/j.jmbbm.2020.104286.
［44］	Puspitasari R，Irnawati D，Widjijono.The effect of zinc oxide（ZnO）nanoparticle concentration on the adhesion of mucin and streptococcus mutans to heat-cured acrylic resin［J］.Dent Mater J，2023，42（6）：791-799.DOI：10.4012/dmj.2023-016.
［45］	Tang FL，Li JL，Xie WH，et al.Bioactive glass promotes the barrier functional behaviors of keratinocytes and improves the Reepithelialization in wound healing in diabetic rats［J］.Bioact Mater，2021，6（10）：3496-3506.DOI：10.1016/j.bioactmat.2021.02.041.
［46］	Chen YY，Sun C，Cao JF，et al.Mechanical properties and in vitro biocompatibility of hybrid polymer-HA/BAG ceramic dental materials［J］.Polymers，2022，14（18）：3774.DOI：10.3390/polym14183774.
［47］	Cui BC，Zhang RR，Sun FB，et al.Mechanical and biocompatible properties of polymer-infiltrated-ceramic-network materials for dental restoration［J］.J Adv Ceram，2020，9（1）：123-128.DOI：10.1007/s40145-019-0341-5.
［48］	Sismanoglu S，Gurcan AT，Yildirim-Bilmez Z，et al.Mechanical properties and repair bond strength of polymer-based CAD/CAM restorative materials［J］.Int J Appl Ceram Technol，2021，18：312-318.DOI：10.1111/ijac.13653.
［49］	Yano HT，Ikeda H，Nagamatsu Y，et al.Effects of alumina airborne-particle abrasion on the surface properties of CAD/CAM composites and bond strength to resin cement［J］.Dent Mater J，2021，40（2）：431-438.DOI：10.4012/dmj.2020-023.
［50］	Wanderico CM，Picolo MZ，Kury M，et al.Alternative surface treatments strategies for bonding to CAD/CAM resin - matrix ceramics［J］.J Adhes Sci Technol，2022，37（8）：1471-1484.DOI：10.1080/01694243.2022.2079333.
［51］	Tuncer B，Aktas G，Baris Guncu M，et al.Effects of surface treatments and cement type on shear bond strength between titanium alloy and All-Ceramic materials［J］.Materials，2023，16（18）：86240.DOI：10.3390/ma16186240.
［52］	Eldafrawy M，Greimers L，Bekaert S，et al.Silane influence on bonding to CAD - CAM composites：An interfacial fracture toughness study［J］.Dent Mater，2019，35（9）：1279-1290.DOI：10.1016/j.dental.2019.05.019.
［53］	Komagata Y，Nagamatsu Y，Ikeda H.Comparative bonding analysis of computer-aided design/computer-aided manufacturing dental resin Composites with various resin cements［J］.J Compos Sci，2023，7（10）：1-11.DOI：10.3390/jcs7100418.
［54］	Bello YD，Di Domenico MB，Magro LD，et al.Bond strength between composite repair and polymer - infiltrated ceramic -network material：Effect of different surface treatments［J］.J Esthet Restor Dent，2019，31（3）：275-279.DOI：10.1111/jerd.12445.
［55］	王淑君，张楚晗，唐一阳，等.自粘接树脂水门汀的临床应用及展望［J/OL］.中华口腔医学研究杂志（电子版），2024，18（4）：276-286.DOI：10.3877/cma.j.issn.1674-1366.2024.04.010.
［56］	David-Pérez M，Ramírez-Suárez JP，Latorre-Correa F，et al.Degree of conversion of resin-cements（light-cured/dual-cured）under different thicknesses of vitreous ceramics：Systematic review［J］.J Prosthodont Res，2022，66（3）：385-394.DOI：10.2186/jpr.JPR_D_20_00090.
［57］	Spitznagel FA，Röhrig S，Langner R，et al.Failure load and fatigue behavior of monolithic translucent zirconia，PICN and rapid-layer posterior single crowns on zirconia implants［J］.Matrials（Basel），2021，14（8）：1990.DOI：10.3390/ma14081990.
［58］	Rosentritt M，Krifka S，Preis V，et al.Dynamic fatigue of composite CAD/CAM materials［J］.J Mech Behav Biomed，2019，98：311-316.DOI：10.1016/j.jmbbm.2019.07.002.
［59］	Coldea A，Fischer J，Swain MV，et al.Damage tolerance of indirect restorative materials（including PICN）after simulated bur adjustments［J］.Dent Mater，2015，31（6）：684-694.DOI：10.1016/j.dental.2015.03.007.
［60］	Elraggal A，Afifi RR，Alamoush RA，et al.Effect of acidic media on flexural strength and fatigue of CAD - CAM dental materials［J］.Dent Mater，2023，39（1）：57-69.DOI：10.1016/j.dental.2022.11.019.
［61］	Turker I，Kursoglu P.Effects of thermal ageing on the mechanical properties of cad-cam ceramic materials［J］.Ceramcs-Silikáty，2023，67（4）：496-504.DOI：10.13168/cs.2023.0049.
［62］	Turgut S，Kılınç H，Bağış B.Effect of UV aging on translucency of currently used esthetic CAD-CAM materials［J］.J Esthet Restor Dent，2019，31（2）：147-152.DOI：10.1111/jerd.12460.

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