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中华口腔医学研究杂志(电子版) ›› 2026, Vol. 20 ›› Issue (03) : 165 -174. doi: 10.3877/cma.j.issn.1674-1366.2026.03.002

前牙种植美学专栏·专家论坛

前牙区钛网暴露并发症的综合防治策略
郭子翔, 于群, 陈青青, 王凌旭, 陈蔚, 潘逸菲, 汤春波()   
  1. 南京医科大学附属口腔医院种植科,口腔疾病研究与防治国家级重点实验室培育建设点,江苏省口腔转化医学工程研究中心,南京 210029
  • 收稿日期:2026-03-14 出版日期:2026-06-01
  • 通信作者: 汤春波

Comprehensive prevention and management strategies for titanium mesh exposure complications in the anterior zone

Zixiang Guo, Qun Yu, Qingqing Chen, Lingxu Wang, Wei Chen, Yifei Pan, Chunbo Tang()   

  1. Department of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing 210029, China
  • Received:2026-03-14 Published:2026-06-01
  • Corresponding author: Chunbo Tang
  • Supported by:
    National Natural Science Foundation of China(82170993); Fundamental Research Funds for the Central Universities(NZ2024037)
引用本文:

郭子翔, 于群, 陈青青, 王凌旭, 陈蔚, 潘逸菲, 汤春波. 前牙区钛网暴露并发症的综合防治策略[J/OL]. 中华口腔医学研究杂志(电子版), 2026, 20(03): 165-174.

Zixiang Guo, Qun Yu, Qingqing Chen, Lingxu Wang, Wei Chen, Yifei Pan, Chunbo Tang. Comprehensive prevention and management strategies for titanium mesh exposure complications in the anterior zone[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2026, 20(03): 165-174.

聚焦前牙美学区引导骨再生(GBR)术后钛网暴露并发症的预防与微创处理策略。前牙区退缩易致轮廓塌陷与"黑三角",钛网的高张力特性常引发软组织裂开。本文系统回顾了钛网暴露的病因学及"伪骨膜"的组织学屏障作用,并探讨基于临床分级的氯己定保守去污及外科干预策略。在预防层面,论述改良"雨披"皮瓣等无张力闭合设计的生物力学优势。针对已暴露缺损,评价游离上皮下结缔组织移植完美的美学重塑地位,以及富血小板纤维蛋白结合微创隧道技术的生物刺激潜力。此外,阐述Er:YAG激光去污及细胞相容性重建的前沿协议,并展望3D打印定制钛网、可吸收缝线固定与载铜抗菌钛合金等生物活性材料的应用前景,旨在构建涵盖"形态设计-被动闭合-微创修补-激光去污-活性材料"的跨学科系统化解决方案。

This study focuses on the prevention and minimally invasive management of titanium mesh exposure following guided bone regeneration in the anterior esthetic zone. Anterior tissue recession often causes contour collapse and "black triangles", while the high tension of titanium meshes frequently induces soft tissue dehiscence. The etiology of mesh exposure and the histological barrier role of the "pseudo-periosteum" are systematically reviewed, alongside evidence-based strategies ranging from conservative chlorhexidine decontamination to surgical interventions based on clinical grading. For prevention, the biomechanical advantages of tension-free passive closure designs, such as the modified poncho technique, are highlighted. To address exposed defects, the gold standard status of subepithelial connective tissue grafts for esthetic remodeling and the biostimulation potential of platelet-rich fibrin combined with minimally invasive tunneling are evaluated. Furthermore, cutting-edge protocols for Er: YAG laser decontamination and cytocompatibility restoration are introduced, anticipating the future applications of 3D-printed customized meshes, resorbable suture fixation, and bioactive copper-bearing titanium alloys. The objective is to provide a comprehensive, interdisciplinary solution encompassing morphological design, passive closure, minimally invasive repair, laser decontamination, and bioactive materials.

图1 前牙行钛网骨增量手术6个月后患者口内像 可见钛网暴露。
图2 钛网骨增量手术拆除钛网后前牙术区情况 可见伪骨膜形成。
图3 改良"雨披"技术(MPT)操作流程 A:切口线(颊面观);B:切口线(咬合面观);C:肌-黏膜下层分离与骨膜翻起;D:腭侧瓣翻起,完成全部翻瓣制备操作;E:引导骨再生(GBR)操作;F:双层缝合关闭创口;a:水平切口,b:垂直及腭侧延伸切口,c:垂直松弛切口。注:图片改编自Wang和de Santis[24],原文依据Creative Commons Attribution License 4.0(CC BY 4.0)开放许可发布。Copyright© 2024 The Author(s). Published by Wolters Kluwer Health,Inc.
表1 结缔组织移植(CTG)与富血小板纤维蛋白(PRF)在前牙钛网暴露软组织修补中的临床特性多维对比分析
表2 掺铒钇铝石榴石激光(Er:YAG)处理不同污染钛表面模型的体外去污效果及其生物学效应
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