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中华口腔医学研究杂志(电子版) ›› 2024, Vol. 18 ›› Issue (02) : 132 -136. doi: 10.3877/cma.j.issn.1674-1366.2024.02.009

综述

富血小板纤维蛋白及其衍生物在口腔种植中的应用进展
李崇才1, 于欣桐2,(), 李邢祎3   
  1. 1. 大连医科大学口腔医学院,大连 116044
    2. 大连医科大学,大连 116044
    3. 大连医科大学附属第一医院,大连 116044
  • 收稿日期:2024-01-05 出版日期:2024-04-01
  • 通信作者: 于欣桐

Application of platelet-rich fibrin and its derivatives in implant dentistry

Chongcai Li1, Xintong Yu2,(), Xingyi Li3   

  1. 1. The Affiliated School of Stomatology, Dalian Medical University, Dalian 116044, China
    2. Dalian Medical University, Dalian 116044, China
    3. The First Affiliated Hospital of Dalian Medical University, Dalian 116044, China
  • Received:2024-01-05 Published:2024-04-01
  • Corresponding author: Xintong Yu
引用本文:

李崇才, 于欣桐, 李邢祎. 富血小板纤维蛋白及其衍生物在口腔种植中的应用进展[J]. 中华口腔医学研究杂志(电子版), 2024, 18(02): 132-136.

Chongcai Li, Xintong Yu, Xingyi Li. Application of platelet-rich fibrin and its derivatives in implant dentistry[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(02): 132-136.

富血小板纤维蛋白(PRF)是第二代血小板浓缩制品,富含生长因子、免疫因子和免疫细胞,可以调节生长代谢,对拔牙后口腔软组织愈合、牙槽嵴位点保存、重症牙周炎症的预防和治疗等方面均有重要意义,近年来,由于制备技术的改进,PRF的衍生物在口腔种植手术中得到广泛推广应用。由于不同的衍生物含有的细胞和细胞因子数量、种类均不同,所以它们在临床中所产生治疗效果也有差别。本文针对不同PRF衍生物在口腔种植的应用进展进行综述。

Platelet-rich fibrin (PRF) is the second generation of platelet concentrates, which is rich in growth factors, immune factors and cells. It can regulate the cellular growth and metabolism, so as to improve the healing of the soft tissue after tooth extraction. In recent years, due to the improvement of the preparation technique, it has been widely used in implant dentistry. Because of the different number and types of cells and cytokines contained by different PRF derivatives, such as A-PRF, L-PRF, their effects on the clinical treatment outcome are also different. This review focused on the application of different PRF derivatives in implant dentistry.

表1 富血小板纤维蛋白(PRF)衍生物的制备方法
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