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中华口腔医学研究杂志(电子版) ›› 2019, Vol. 13 ›› Issue (02) : 124 -128. doi: 10.3877/cma.j.issn.1674-1366.2019.02.011

所属专题： 口腔医学； 文献；

综述

富血小板纤维蛋白对软组织修复与再生影响的研究进展
唐一月1, 余占海1,†()   
  1. 1. 兰州大学口腔医学院（医院）口腔种植科　730000
  • 收稿日期:2019-01-22 出版日期:2019-04-01
  • 通信作者: 余占海

Research progress on the effects of platelet-rich fibrin on soft tissue repair and regeneration

Yiyue Tang1, Zhanhai Yu1,†()   

  1. 1. Department of Oral Implantology, School/Hospital of Stomatology, Lanzhou University, Lanzhou 730000, China
  • Received:2019-01-22 Published:2019-04-01
  • Corresponding author: Zhanhai Yu
  • About author:
    Corresponding author: Yu Zhanhai, Email:
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唐一月, 余占海. 富血小板纤维蛋白对软组织修复与再生影响的研究进展[J]. 中华口腔医学研究杂志(电子版), 2019, 13(02): 124-128.

Yiyue Tang, Zhanhai Yu. Research progress on the effects of platelet-rich fibrin on soft tissue repair and regeneration[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2019, 13(02): 124-128.

近年来随着组织工程的不断发展，关于损伤组织修复与再生的研究层出不穷，其中富血小板纤维蛋白（PRF）用于软组织修复及再生的问题成为研究热点。PRF是一种自体血来源的富含细胞生长因子的新型生物材料，被誉为第二代血小板浓缩物。本文就PRF对软组织修复及再生影响的体内研究，体外研究及临床研究作一综述。

关键词: 富血小板纤维蛋白, 生长因子, 软组织, 再生

In recent years, with the development of tissue engineering, researches on the repair and regeneration of defected tissue have emerged in an endless stream. The issue of platelet-rich fibrin (PRF) for soft tissue repair and regeneration is a hot topic. PRF is a new biological material derived from autologous blood cells and rich in cell growth factors, which is known as the second generation of platelet concentrates. This article reviews the in vivo, in vitro and clinical studies of the effects of PRF on soft tissue repair and regeneration.

Key words: Platelet-rich fibrin, Growth factors, Soft tissue, Regeneration
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