Effect of fluoride varnish on caries prevention of partially erupted first permanent molars in rural areas

doi:10.3877/cma.j.issn.1674-1366.2015.04.012

Abstract

Abstract:

Objective

To explore the clinical effect of fluoride varnish on caries prevention of partially erupted first permanent molars in rural areas.

Methods

The sample included 476 children aged 6-7 years old based on simple random sampling, with a total of 1462 partially erupted first permanent molars. The children were randomly divided into test group(n=212, 697 molars)and control group(n=264, 765 molars). The test group was semiannually applied with fluoride varnish (Duraphat?)for 5 times, and the control group was not applied in two years. All dental caries of all the children were checked every 6 months.

Results

No significantly statistical difference was found in the caries incidence rate or mean DMFS between 2 groups after 6 months(P_{incidence rate}=1.000; t_{mean DMFS}=0.005, P_{mean DMFS}=0.996)or after 12 months(χ²_{incidence rate}=1.489, P_{incidence rate}=0.222; t_{mean DMFS}=1.417, P_{mean DMFS}=0.157). The caries incidence rate and mean DMFS of test group were significantly lower than those of control group(χ²_{incidence rate}=11.645, P_{incidence rate}=0.001; t_{mean DMFS}=3.408, P_{mean DMFS}=0.001)after 24 months.

Conclusion

Application of fluoride varnish for the partially erupted first permanent molars in rural areas can effectively reduce the incidence rate of caries, which was worth being popularized in clinic.

Key words: Fluorides, Topical, Molar, Dental caries

Xueqing Yuan, Wei Luo, Xiaoying Chen. Effect of fluoride varnish on caries prevention of partially erupted first permanent molars in rural areas[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2015, 09(04): 318-321.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhkqyxyjzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-1366.2015.04.012

https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2015/V09/I04/318

Figures/Tables 3

References 20

[1]	齐小秋.第三次全国口腔健康流行病学调查报告[R].北京：人民卫生出版社，2008.
[2]	查光玉，江银华，樊慧红，等.丽水市儿童六龄牙龋病现况调查[J].上海口腔医学，2010，19(3): 255-258.
[3]	Suwansingha O, Rirattanapong P. Effect of fluoride varnish on caries prevention of partially erupted of permanent molar in high caries risk[J]. Southeast Asian J Trop Med Public Health, 2012, 43(3): 808-813.
[4]	Blinkhorn A, Davies R. Using fluoride varnish in the practice[J]. Br Dent J, 1998, 185(6): 280-281.
[5]	Lippert F. Fluoride release from fluoride varnishes under acidic conditions[J]. J Clin Pediatr Dent, 2014, 39(1): 35-39.
[6]	Hawkins R, Locker D, Noble J, et al. Prevention. Part 7: professionally applied topical fluorides for caries prevention[J]. Br Dent J, 2003, 195(6): 313-317.
[7]	Marinho VC, Worthington HV, Walsh T, et al. Fluoride varnishes for preventing dental caries in children and adolescents[J]. Cochrane Database Syst Rev, 2013(7): CD002279.
[8]	Marinho VC. Evidence-based effectiveness of topical fluorides[J]. Adv Dent Res, 2008, 20(1): 3-7.
[9]	Sköld-Larsson K, Modéer T, Twetman S. Fluoride concentration in plaque in adolescents after topical application of different fluoride varnishes[J]. Clin Oral Investig, 2000, 4(1): 31-34.
[10]	Jeevarathan J, Deepti A, Muthu MS, et al. Effect of fluoride varnish on Streptococcus mutans counts in plaque of caries-free children using Dentocult SM strip mutans test: a randomized controlled triple blind study[J]. J Indian Soc Pedod Prev Dent, 2007, 25(4): 157-163.
[11]	Chau NP, Pandit S, Jung JE, et al. Evaluation of Streptococcus mutans adhesion to fluoride varnishes and subsequent change in biofilm accumulation and acidogenicity[J]. J Dent, 2014, 42(6): 726-734.
[12]	蒋贤军，胡德渝，尹伟.含氟涂料预防儿童和青少年龋齿的研究进展[J/CD].中华口腔医学研究杂志：电子版，2012，6(5): 468-471.
[13]	Marinho VC, Higgins JP, Logan S, et al. Topical fluoride (toothpastes, mouthrinses, gels or varnishes)for preventing dental caries in children and adolescents[J]. Cochrane Database Syst Rev, 2003(4): CD002782.
[14]	黄璟，陈智，郭毅.局部用氟预防儿童龋齿的系统评价[J].中国循证医学杂志，2012，12(7): 848-854.
[15]	Marinho VC, Higgins JP, Sheiham A, et al. One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes)versus another for preventing dental caries in children and adolescents[J]. Cochrane Database Syst Rev, 2004(1): CD002780.
[16]	Beltrán-Aguilar ED, Goldstein JW, Lockwood SA. Fluoride varnishes. A review of their clinical use, cariostatic mechanism, efficacy and safety[J]. J Am Dent Assoc, 2000, 131(5): 589-596.
[17]	Houpt M, Koenigsberg S, Shey Z. The effect of prior toothcleaning on the efficacy of topical fluoride treatment. Two-year results[J]. Clin Prev Dent, 1983, 5(4): 8-10.
[18]	孔宇，杨青岭，赵玥，等.多乐氟氟化钠护齿剂联合窝沟封闭剂预防龋病的效果研究[J].黑龙江医药科学，2014，37(4): 62-64.
[19]	Bravo M, Montero J, Bravo JJ, et al. Sealant and fluoride varnish in caries: a randomized trial[J]. J Dent Res, 2005, 84(12): 1138-1143.
[20]	蒋纯蓉.窝沟封闭加局部用氟对龋高危儿童防龋效果观察[J].广东牙病防治，2014，22(11): 582-584.

时间	组别	患龋人数	受检人数	患龋率	χ2值	P值
0个月	试验组	108	212	50.94%	0.002	0.968
	对照组	134	264	50.76%
	合计	242	476	50.84%
6个月	试验组	112	212	52.83%	0.041	0.839
	对照组	137	264	51.89%
	合计	249	476	52.31%
12个月	试验组	118	212	55.66%	0.008	0.930
	对照组	148	264	56.06%
	合计	266	476	55.88%
24个月	试验组	128	209^a	61.24%	2.113	0.146
	对照组	176	260^a	67.69%
	合计	304	469^a	64.82%

时间	组别	患龋人数	受检人数	患龋率	χ2值	P值
0个月	试验组	108	212	50.94%	0.002	0.968
	对照组	134	264	50.76%
	合计	242	476	50.84%
6个月	试验组	112	212	52.83%	0.041	0.839
	对照组	137	264	51.89%
	合计	249	476	52.31%
12个月	试验组	118	212	55.66%	0.008	0.930
	对照组	148	264	56.06%
	合计	266	476	55.88%
24个月	试验组	128	209^a	61.24%	2.113	0.146
	对照组	176	260^a	67.69%
	合计	304	469^a	64.82%

时间	组别	发病人数	受检人数	龋病发病率	χ²值	P值
6个月	试验组	2	212	0.94%	-^a	1.000
6个月	对照组	3	264	1.14%	-^a	1.000
12个月	试验组	4	212	1.89%	1.489	0.222
12个月	对照组	10	264	3.79%	1.489	0.222
24个月	试验组	10	209	4.78%	11.465	0.001
24个月	对照组	37	260	14.23%	11.465	0.001

时间	组别	发病人数	受检人数	龋病发病率	χ²值	P值
6个月	试验组	2	212	0.94%	-^a	1.000
6个月	对照组	3	264	1.14%	-^a	1.000
12个月	试验组	4	212	1.89%	1.489	0.222
12个月	对照组	10	264	3.79%	1.489	0.222
24个月	试验组	10	209	4.78%	11.465	0.001
24个月	对照组	37	260	14.23%	11.465	0.001

时间	组别	DMFS	受检人数	龋面均(±)	t值	P值
6个月	试验组	4	212	0.02 ± 0.01	0.005	0.996
6个月	对照组	5	264	0.02 ± 0.01	0.005	0.996
12个月	试验组	6	212	0.03 ± 0.02	1.417	0.157
12个月	对照组	17	264	0.06 ± 0.02	1.417	0.157
24个月	试验组	16	209	0.08 ± 0.02	3.408	0.001
24个月	对照组	59	260	0.23 ± 0.04	3.408	0.001

Please choose a citation manager

Content to export