Progress of research on quercetin against oral diseases

doi:10.3877/cma.j.issn.1674-1366.2024.02.007

Abstract

Abstract:

Quercetin is a safe and readily available natural polyphenolic compound. It has been found that quercetin exhibits significant antioxidant, anti-inflammatory, antibacterial, and apoptosis-regulating effects through a variety of mechanisms, and its diversity of mechanisms and safety have enabled it to be widely used in a wide range of disease prevention and treatment. Many in vitro and animal experiments have shown that quercetin can inhibit the development of oral cancer, treat oral mucosal diseases, periodontal diseases and caries, showing good therapeutic effects on oral diseases. The effectiveness of quercetin in clinical applications has been reported in several papers in many fields, such as nerves and joints, but there are only a few reports on clinical applications for oral diseases. This article reviewed the properties of quercetin as a drug for oral disease control, as well as its application and mechanism in a variety of oral disease control studies, with a view to promoting the clinical application of quercetin in oral disease control and providing a safe and reliable option for oral disease control.

Key words: Quercetin, Apoptosis, Oral neoplasms, Oral mucosal disease, Periodontitis, Dental caries

Yuanjie Luo, Jingmei Yang, Shu Meng, Yibo Ao, Daonan Shen. Progress of research on quercetin against oral diseases[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(02): 117-122.

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