Clinical and radiographic evaluation of coralline hydroxyapatite treatment in different types of peri-implant bone defects

doi:10.3877/cma.j.issn.1674-1366.2011.02.013

Abstract

Abstract:

Objective

To evaluate the effects of coralline hydroxyapatite （CHA） served as bone graft in patients with different types of peri-implant osseous defects， and to compare the survival and success rates of implants placed with or without CHA.

Methods

Forty nine patients with fifty eight peri-implant osseous defects （including dehiscence， fenestration， and horizontal type） were treated with CHA combined with resorbable membranes（the test group），while fifty nine patients with ninty implants were inserted into adequate volume of nonaugmented bones （the control group）.When patients took the second stage surgery， examinations were performed to observe the effects of bone regeneration and changes of bone density of bone grafts.The survival/success rates and marginal bone levels of implants were compared between the test and the control group， and also studied in different types of bone defects in the test group.

Results

The osseointegration rates were 94.8% and 96.7% respectively in the test and control group at the second stage surgery.In follow-up （6-24 months after loading）， the success rate of the test implants was 94.5% and the control ones 97.7%.In the test group， the survival rate was 100%， the bone regeneration success rate 89.1%， and forty nine implants achieved complete bone fill.The dehiscence type of peri-implant osseous defects had better bone regenaration effect and prognosis than the horizontal type， but inferior to the fenestration type， however the differences between the three typs were not statistically significant.Radiographic observation revealed that density of the coralline hydroxyapatite reduced with the time.No significant differences of marginal bone loss were observed between the test and control groups， and among the three types of the test group.

Conclusions

Coralline hydroxyapatite with good biocompatibility is an ideal bone graft substitute to induce bone regeneration and repair the bone defects effectively.Treated with coralline hydroxyapatite， the implants with peri-implant defects had similar survival/success rates and crestal bone levels as those implanted in adequate volume of bones.

Key words: Coralline hydroxyapatite, Guided bone regeneration, Bone defects, Clinical effects, Degradation

Siriguleng LI, Xiao-wen HU, Chao ZHANG, Ling-wei LI, Cui-jun LI. Clinical and radiographic evaluation of coralline hydroxyapatite treatment in different types of peri-implant bone defects[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2011, 5(02): 192-204.

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Figures/Tables 16

References 21

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组别	性别（例）			种植系统（枚）
组别	男	女	合计	XIVE	Replace	合计
实验组	26	23	49	41	17	58
对照组	31	27	58	62	28	90
合计	57	50	107	103	45	148

组别	性别（例）			种植系统（枚）
组别	男	女	合计	XIVE	Replace	合计
实验组	26	23	49	41	17	58
对照组	31	27	58	62	28	90
合计	57	50	107	103	45	148

组别	上颌骨				下颌骨				合计
组别	切牙	尖牙	双尖牙	磨牙	切牙	尖牙	双尖牙	磨牙	合计
实验组	18	7	13	3	3	0	8	6	58
对照组	12	4	8	9	4	4	11	38	90
合计	30	11	21	12	7	4	19	44	148

组别	上颌骨				下颌骨				合计
组别	切牙	尖牙	双尖牙	磨牙	切牙	尖牙	双尖牙	磨牙	合计
实验组	18	7	13	3	3	0	8	6	58
对照组	12	4	8	9	4	4	11	38	90
合计	30	11	21	12	7	4	19	44	148

缺损类型	上颌骨				下颌骨				合计
缺损类型	切牙	尖牙	双尖牙	磨牙	切牙	尖牙	双尖牙	磨牙	合计
裂隙状	11	2	8	2	1	0	5	3	32
开窗式	3	4	3	0	0	0	1	0	11
水平型	4	1	2	1	2	0	2	3	15
合计	18	7	13	3	3	0	8	6	58

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