A strong bone adhesive promotes the reconstruction of oral hard tissue

doi:10.3877/cma.j.issn.1674-1366.2024.01.001

Abstract

Abstract:

Biodegradable bone adhesives attract increasing attention in biomaterial research. These adhesives have exhibited great potential in fracture fixation and bone defect treatment, but they are not commonly used in Dentistry. Recently, researchers have developed a degradable super bone adhesive with excellent adhesion, biocompatibility and performance in promoting bone regeneration. Their findings made new breakthroughs in bone adhesion, tooth bonding and bone regeneration. This article aimed to review their findings and discuss the related research prospects.

Key words: Bone and bones, Adhesives, Bone regeneration, Mouth, Bone defect

Hao Li, Xiuxiang Wei, Xiaoxia Zhong. A strong bone adhesive promotes the reconstruction of oral hard tissue[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(01): 1-4.

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References 27

[1]	Bingol HB，Bender JCME，Opsteen JA，et al. Bone adhesive materials：From bench to bedside[J]. Mater Today Bio，2023，19：100599. DOI：10.1016/j.mtbio.2023.100599.
[2]	Hu S，Wang S，He Q，et al. A mechanically reinforced super bone glue makes a leap in hard tissue strong adhesion and augmented bone regeneration[J]. Adv Sci（Weinh），2023，10（11）：e2206450. DOI：10.1002/advs.202206450.
[3]	Leggat PA，Smith DR，Kedjarune U. Surgical applications of cyanoacrylate adhesives：A review of toxicity[J]. ANZ J Surg，2007，77（4）：209-213. DOI：10.1111/j.1445-2197.2007.04020.x.
[4]	Hafeez AA，Furmeen SS，Durairaj D，et al. Application of N-butyl-2-cyanoacrylate for the treatment of comminuted fractures in the anterior wall of the maxillary sinus：A prospective clinical study[J]. Cureus，2023，15（2）：e35487. DOI：10.7759/cureus.35487.
[5]	Melrose J. High performance marine and terrestrial bioadhesives and the biomedical applications they have inspired[J]. Molecules，2022，27（24）：8982. DOI：10.3390/molecules27248982.
[6]	Shokri M，Dalili F，Kharaziha M，et al. Strong and bioactive bioinspired biomaterials，next generation of bone adhesives[J]. Adv Colloid Interface Sci，2022，305：102706. DOI：10.1016/j.cis.2022.102706.
[7]	Fan HL，Wang JH，Gong JP. Barnacle cement proteins-inspired tough hydrogels with robust，long-lasting，and repeatable underwater adhesion[J]. Adv Funct Mater，2021，31（11）：2009334. DOI：10.1002/adfm.202009334.
[8]	Li A，Jia M，Mu Y，et al. Humid bonding with a water-soluble adhesive inspired by mussels andsandcastle worms[J]. Macromol Chem Phys，2015，216（4）：450-459. DOI：10.1002/macp.201400513.
[9]	Millar NL，Bradley TA，Walsh NA，et al. Frog glue enhances rotator cuff repair in a laboratory cadaveric model[J]. J Shoulder Elbow Surg，2009，18（4）：639-645. DOI：10.1016/j.jse.2008.12.007.
[10]	Tzagiollari A，McCarthy HO，Levingstone TJ，et al. Biodegradable and biocompatible adhesives for the effective stabilisation，repair and regeneration of bone[J]. Bioengineering（Basel），2022，9（6）：250. DOI：10.3390/bioengineering9060250.
[11]	Hasani-Sadrabadi MM，Sarrion P，Pouraghaei S，et al. An engineered cell-laden adhesive hydrogel promotes craniofacial bone tissue regeneration in rats[J]. Sci Transl Med，2020，12（534）：eaay6853. DOI：10.1126/scitranslmed.aay6853.
[12]	Liu YH，Zhu Z，Pei XB，et al. ZIF-8-modified multifunctional bone-adhesive hydrogels promoting angiogenesis and osteogenesis for bone regeneration[J]. ACS Appl Mater Interfaces，2020，12（33）：36978-36995. DOI：10.1021/acsami.0c12090.
[13]	Xu LJ，Gao S，Zhou R，et al. Bioactive pore-forming bone adhesives facilitating cell ingrowth for fracture healing[J]. Adv Mater，2020，32（10）：e1907491. DOI：10.1002/adma.201907491.
[14]	王星月.新型强粘附性载药水凝胶用于增强骨-植入物固定及抗感染的研究[D].长春：吉林大学，2022.
[15]	Wang B，Liu J，Niu D，et al. Mussel-inspired bisphosphonated injectable nanocomposite hydrogels with adhesive，self-healing，and osteogenic properties for bone regeneration[J]. ACS Appl Mater Interfaces，2021，13（28）：32673-32689. DOI：10.1021/acsami.1c06058.
[16]	Sánchez-Fernández MJ，Hammoudeh H，Félix Lanao RP，et al. Bone-adhesive materials：Clinical requirements，mechanisms of action，and future perspective[J]. Adv Mater Interfaces，2019，6（4）：1802021. DOI：10.1002/admi.201802021.
[17]	Renner T，Otto P，Kübler AC，et al. Novel adhesive mineral-organic bone cements based on phosphoserine and magnesium phosphates or oxides[J]. J Mater Sci Mater Med，2023，34（4）：14. DOI：10.1007/s10856-023-06714-6.
[18]	Moazami S，Kharaziha M，Emadi R，et al. Multifunctional bioinspired bredigite-modified adhesive for bone fracture healing[J]. ACS Appl Mater Interfaces，2023，15（5）：6499-6513. DOI：10.1021/acsami.2c20038.
[19]	Guo Q，Chen J，Wang J，et al. Recent progress in synthesis and application of mussel-inspired adhesives[J]. Nanoscale，2020，12（3）：1307-1324. DOI：10.1039/c9nr09780e.
[20]	Kunrath MF，Dahlin C. The impact of early saliva interaction on dental implants and biomaterials for oral regeneration：An overview[J]. Int J Mol Sci，2022，23（4）：2024. DOI：10.3390/ijms23042024.
[21]	Howard KC，Gonzalez OA，Garneau-tsodikova S. Porphyromonas gingivalis：Where do we stand in our battle against this oral pathogen？[J]. RSC Med Chem，2021，12（5）：666-704. DOI：10.1039/d0md00424c.
[22]	Xu L，Ye Q，Xie J，et al. An injectable gellan gum-based hydrogel that inhibits Staphylococcus aureus for infected bone defect repair[J]. J Mater Chem B，2022，10（2）：282-292. DOI：10.1039/d1tb02230j.
[23]	Ramasamy SK，Kusumbe AP，Schiller M，et al. Blood flow controls bone vascular function and osteogenesis[J]. Nat Commun，2016，7：13601. DOI：10.1038/ncomms13601.
[24]	李苑，苏毅，江飞，等.新型通用型粘接剂对牙本质粘接强度的体外研究[J].南京医科大学学报（自然科学版），2020，40（5）：754-758+762. DOI：10.7655/NYDXBNS20190526.
[25]	Wen B，Dai YG，Han X，et al. Biomineralization-inspired mineralized hydrogel promotes the repair and regeneration of dentin/bone hard tissue[J]. NPJ Regen Med，2023，8（1）：11. DOI：10.1038/s41536-023-00286-3.
[26]	Li Y，Zhu J，Zhang X，et al. Drug-delivery nanoplatform with synergistic regulation of angiogenesis-osteogenesis coupling for promoting vascularized bone regeneration[J]. ACS Appl Mater Interfaces，2023，15（14）：17543-17561. DOI：10.1021/acsami.2c23107.
[27]	Pirmoradian M，Hooshmand T，Najafi F，et al. Design，synthesis，and characterization of a novel dual cross-linked gelatin-based bioadhesive for hard and soft tissues adhesion capability[J]. Biomed Mater，2022，17（6）. DOI：10.1088/1748-605X/ac9268.

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