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Chinese Journal of Stomatological Research(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (06): 375-381. doi: 10.3877/cma.j.issn.1674-1366.2021.06.008

• Review • Previous Articles     Next Articles

The role of silicon ion in the field of bone regeneration

Weiyang Chen1, Jun Tian1, Xi Wei1,()   

  1. 1. Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2021-02-22 Online:2021-12-01 Published:2022-01-21
  • Contact: Xi Wei
  • Supported by:
    National Natural Science Foundation of China(81970925); Financial Fund for High-Caliber Hospital Construction of Guangdong Province(174-2018-XMZC-0001-03-0125/A-01)

Abstract:

Silicon ion participates in the physiological process of bone tissue formation and bone tissue mineralization, and plays an important role in bone metabolism. Deficiency of Silicon will lead to bone deformation. Si-containing bioactive materials can promote angiogenesis as well as osteogenesis, on the other hand, inhibit osteoclast differentiation. These mterials also exert immunomodulatory effects through releasing Si-containing ionic products, which can effectively facilitate bone tissue repair and regeneration. In this paper, the role of silicon ion in the field of bone regeneration is reviewed.

Key words: Silicon, Bone regeneration, Osteogenic differentiation, Osteoblasts

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