The effects of simulating static magnetic fields of magnetic attachments on the differentiation of osteoblasts

doi:10.3877/cma.j.issn.1674-1366.2011.02.007

Abstract

Abstract:

Objective

To explore the biological effects of static magnetic fields （SMF） of dental magnetic attachment system with different intensities on osteocalcin （OCN） activities of osteoblasts.

Methods

In this study， the cultured rat osteoblasts were exposed continuously to 12.5 mT， 125 mT， and 250 mT SMF for one， three， five， and seven days， respectively.While，controls were also set up free of SMF.The activities of cellular OCN were examined by radioimmunoassay and statistical analysis was performed.

Results

Osteoblasts exposed to 12.5 mT， 125 mT， and 250 mT SMF for one day and three days did not exhibit significant differences on OCN activities， as compared to those of the control group（P ＞0.05）.However， when the SMF exposure continued to five days and seven days， the cellular OCN activities of the test groups were significantly higher（P＜0.05）.And no difference was found between the three SMF exposure groups（P ＞0.05）.

Conclusions

Under this experimental condition， the static magnetic fields of magnetic attachments can stimulate OCN activities of osteoblasts， as to enhance the differentiation of osteoblasts.

Key words: Magnetic attachments, Static magnetic fields, Osteoblasts, Osteocalcin

Yu ZHAO, Bing-yan LI, Li DU, Yong-lie CHAO. The effects of simulating static magnetic fields of magnetic attachments on the differentiation of osteoblasts[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2011, 5(02): 151-155.

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https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2011/V5/I02/151

Figures/Tables 2

References 14

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组别	静磁场加载时间（d）				P
组别	1	3	5	7	P
对照组	3.402±0.068	3.266±0.060	3.382±0.037	3.473±0.034	0.080
12.5 mT组	3.157±0.173	3.344±0.027	4.330±0.017^a	4.368±0.059^a	0.001
125 mT组	3.288±0.02	3.267±0.174	4.417±0.161^a	4.434±0.108^a	0.000
250 mT组	3.389±0.074	3.406±0.396	4.520±0.194^a	4.542±0.327^a	0.001
P	0.068	0.860	0.000	0.000	0.000^b

组别	静磁场加载时间（d）				P
组别	1	3	5	7	P
对照组	3.402±0.068	3.266±0.060	3.382±0.037	3.473±0.034	0.080
12.5 mT组	3.157±0.173	3.344±0.027	4.330±0.017^a	4.368±0.059^a	0.001
125 mT组	3.288±0.02	3.267±0.174	4.417±0.161^a	4.434±0.108^a	0.000
250 mT组	3.389±0.074	3.406±0.396	4.520±0.194^a	4.542±0.327^a	0.001
P	0.068	0.860	0.000	0.000	0.000^b

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