Temporomandibular joint disorder (TMD) is a disease with a high incidence in dental clinics except for caries, periodontal disease, and malocclusion. Due to the unknown etiology, ununified diagnosis and treatment mode, and unclear diagnosis and treatment outcome, TMD is recognized as an intractable disease. The key of diagnosis and treatment for TMD includes the articular disc, condylar bone, masticatory muscles, and occlusion. Recently, more and more attention has been paid to psychotherapy. However, there have not been established systematic diagnosis and treatment models. Based on the previous unique diagnosis and treatment model, we put forward the 'MOODE’ novel treatment model including disc, occlusion, osseous tissue, muscle, and emotion. We hope to provide a more systematic, comprehensive, and multidimensional diagnosis and treatment model for TMD.