Research progress in the pathogenesis of taurodontism

doi:10.3877/cma.j.issn.1674-1366.2023.02.002

Abstract

Abstract:

Taurodontism is a developmental disturbance of pulp chamber, which manifested as a large pulp chamber and short roots with a broad enamel-cenmental junction in the molar. The pathogenesis of taurodontism has not yet been fully elucidated. The main theories about the pathogenesis include atavism, concomitant symptoms of hereditary diseases and abnormal root development. Many biological molecules such as nfi-c, WNT10A and KIF4A have also been proved to be closely related to the occurrence of taurodontism. This review focuses on the etiology of taurodontism in order to promote the clinical knowledge of the diagnosis and treatment of the disease.

Key words: Taurodontism, Etiology, Hereditary disease, Developmental disturbance

Ling Lin, Pei Li, Wei Zhao. Research progress in the pathogenesis of taurodontism[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(02): 75-80.

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