Fibrous dysplasia (FD) is a benign bone lesion characterized by the replacement of normal bone tissue with fibrous structures and disorganized woven bone. This lesion often affects the craniofacial skeleton, particularly the maxilla and mandible. Whether dental implant surgery can be successfully performed in patients with FD lacks consensus. Our department admitted a patient with missing right upper posterior teeth and fibrous dysplasia of the right maxilla. Two implants were placed in the edentulous region, one of which was partially located within the lesion area. Six months later, CBCT revealed successful osseointegration. Subsequently, a fixed bridge was fabricated, resulting in satisfactory functional restoration of mastication. At the one-year follow-up, the patient remained asymptomatic, with no implant mobility observed clinically. Repeat CBCT imaging revealed no evidence of peri-implant bone resorption, and stable osseointegration was maintained. Collectively, this case suggests that fibrous dysplasia is not an absolute contraindication for dental implant rehabilitation. However, successful outcomes necessitate meticulous preoperative assessment, including precise lesion classification, adequate evaluation of host bone quantity and quality, and careful case selection to mitigate the risk of implant failure.