Acidogenicity and aciduricity of Streptococcus mutans isolated from the saliva of individuals with radiation-induced caries

doi:10.3877/cma.j.issn.1674-1366.2011.05.006

Abstract

Abstract:

Objective

To explore the acidogenicity and aciduricity of Streptococcus mutans （S.mutans） isolated from individuals with radiation-induced caries and non-caries.

Methods

Total of 40 strains isolated from individuals with radiation-induced caries （the experimental group） and non-caries （the control group）（n=20 per group）， were inoculated into PYG liquid medium with different initial pH （ranging from 4.0 to 7.0 at 0.5 intervals）. The terminal pH of medium was detected by pH meter to evaluate the acidogenicity， and the A₆₀₀ was measured by spectrophotometer to assess the aciduricity.

Results

The acidogenicity and aciduric abilities of S.mutans isolated from the experimental group were significantly higher than those isolated from the control group （P＜0. 05）.

Conclusion

S.mutans strains isolated from the saliva of individuals with radiation-induced caries showed higher acidogenecity and aciduricability.

Key words: Dental caries, Radiotherapy, Streptococcus mutans, Acidogenicity, Aciduricity

Jiang-feng LIU, Zhi-feng CHEN, Hai-qiong FANG, Ping GAO, Wei-ming YU, Xiao-feng LIU, An-xun WANG. Acidogenicity and aciduricity of Streptococcus mutans isolated from the saliva of individuals with radiation-induced caries[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2011, 5(05): 483-487.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhkqyxyjzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-1366.2011.05.006

https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2011/V5/I05/483

Figures/Tables 2

References 13

1	Hong CH， Napeñas JJ， Hodgson BD， et al. A systematic review of dental disease in patients undergoing cancer therapy. Support Care Cancer， 2010，18（8）:1007-1021.
2	Huber MA， Terezhalmy GT. The head and neck radiation oncology patient. Quintessence Int， 2003，34（9）:693-717.
3	Napimoga MH， Kamiya RU， Rosa RT， et al. Genotypic diversity and virulence traits of Streptococcus mutans in caries-free and caries-active individuals. J Med Microbiol， 2004，53（7）:697-703.
4	马瑞，姜云涛，姜葳，等. 不同龋敏感者变异链球菌临床分离株的致龋特性. 上海交通大学学报（医学版），2007，27（2）:141-143.
5	Zhang L， Foxman B， Drake DR， et al. Comparative whole-genome analysis of Streptococcus mutans isolates within and among individuals of different caries status. Oral Microbiol Immunol， 2009，24（3）:197-203.
6	罗京伟，徐国镇. 鼻咽癌治疗的进展. 中华耳鼻喉科杂志， 2004，39（8）:509-512.
7	Andrews N. Dental implication and management of head and neck radiotherapy patients. Ann R Australas Coll Dent Surg， 2000，15（2）:90-97.
8	Vuotila T， Ylikonntiola L， Sorsa T， et al. The relationship between MMPs and Phin whole saliva of radiated head and neck cancer patients.J Oral Pathol Med， 2002，31（6）:329-338.
9	Tong HC， Gao XJ， Dong XZ， et al. Non-mutans streptococci in patients receiving radiotherapy in the head and neck area. Caries Res，2003，37（4）:261-266.
10	Hu JY， Li YQ， Smales RJ， et al. Restoration of teeth with more-viscous glass ionomer cements following radiation-induced caries. Int Dent J， 2005，52（6）:445-448.
11	Powell LV. Caries risk assessment: relevance to the practitioner. J Am Dent Assoc， 1998，129（3）:349-353.
12	曹元书，刘兴容. 不同龋敏感儿童变形链球菌临床分离株产酸、耐酸能力实验研究. 实用口腔医学杂志， 2009，25（1）:103-106.
13	樊明文. 牙体牙髓病学.3 版. 北京:人民卫生出版社，2009:367.

组别	△pH
组别	7.0	6.5	6.0	5.5	5.0
实验组	3.42 ± 0.23	2.61 ± 0.24	2.20 ± 0.18	1.52 ± 0.27	0.85 ± 0.27
对照组	2.82 ± 0.32	2.38 ± 0.32	1.78 ± 0.20	1.17 ± 0.21	0.45 ± 0.23
P	＞ 0.05	＞ 0.05	＞ 0.05	＞ 0.05	＜ 0.05

组别	△pH
组别	7.0	6.5	6.0	5.5	5.0
实验组	3.42 ± 0.23	2.61 ± 0.24	2.20 ± 0.18	1.52 ± 0.27	0.85 ± 0.27
对照组	2.82 ± 0.32	2.38 ± 0.32	1.78 ± 0.20	1.17 ± 0.21	0.45 ± 0.23
P	＞ 0.05	＞ 0.05	＞ 0.05	＞ 0.05	＜ 0.05

组别	A ₆₀₀
组别	7.0	6.5	6.0	5.5	5.0
实验组	1.402 ± 0.123	1.391 ± 0.224	1.120 ± 0.118	1.052 ± 0.127	0.685 ± 0.135
对照组	1.382 ± 0. 132	1.238 ± 0.232	1.078 ± 0.120	0.517 ± 0.121	0.345 ± 0.123
P	＞ 0.05	＞ 0.05	＞ 0.05	＞ 0.05	＜ 0.05

组别	A ₆₀₀
组别	7.0	6.5	6.0	5.5	5.0
实验组	1.402 ± 0.123	1.391 ± 0.224	1.120 ± 0.118	1.052 ± 0.127	0.685 ± 0.135
对照组	1.382 ± 0. 132	1.238 ± 0.232	1.078 ± 0.120	0.517 ± 0.121	0.345 ± 0.123
P	＞ 0.05	＞ 0.05	＞ 0.05	＞ 0.05	＜ 0.05

[1]	Xuebing Shi, Yingdong Xie, Ni Xie, Chaoli Xu, Bin Yang, Guo Sun. Acoustic radiation force imaging for evaluating efficacy of radiotherapy in unresectable hepatocellular carcinoma patients with portal vein tumor thrombus [J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2024, 21(08): 778-784.
[2]	Xiangjun Chen, Li Yu, Xing Wang, Junqing Liang, Di Wu, Zhijun Li. Clinical efficacy study of different methods combined with radiotherapy in the repair of thin keloid [J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2024, 19(03): 215-222.
[3]	Yue Wang, Yuanmeng Yang, Teck-Ek Ho, Wen Meng, Xinyu Chen, Fei Li, Zhanmin Lu, Haixia Lu. Research progress on caries prevention and treatment based on oral microecology [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(06): 391-396.
[4]	Wuli Li, Chunhui Zhao, Cheng Sun, Guiting Zheng, Danjie Meng, Song Li. A clinical comparison of selective and complete caries removal techniques in the management of deep carious lesions proximal to the pulp in permanent teeth [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(04): 243-249.
[5]	Daiqin Li, Peijie Liu. Value of dynamic enhanced magnetic resonance imaging in evaluating the efficacy and prognosis of middle and advanced low rectal cancer after concurrent chemoradiotherapy [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(01): 100-103.
[6]	DaRebai· ReDati, Lin Liu, Weimin Zhao, Tao Meng, Cheng Lei, Bo Jin, Jianjun Bi, Xinyu Li, Haijiang Wang. Clinical observation of lateral lymph node dissection after neoadjuvant chemoradiotherapy for middle and low rectal cancer [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2024, 18(04): 415-418.
[7]	Weizhou Wu, Qiongren Wang, Xiongyu Zhan, Mingxing Zheng, Yaxian Li. Multidisciplinary consultation on difficult cases in Guangdong Urological Association (Phase 16): sarcomatoid renal cell carcinoma of the left kidney [J]. Chinese Journal of Endourology(Electronic Edition), 2024, 18(05): 525-529.
[8]	Guiping Zhang, Yonglin Qiu, Qiting Zhan, Ledong Sun. Prognostic significance of serum Ape1/Ref-1 for the radioactive lung injury in patients with advanced non-small cell lung cancer [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2024, 17(04): 519-523.
[9]	Zhipeng Sun, Bin Shu, Liang Wang, Xin Huang, Pengfei Wang, Guangxin Li, Xiaojuan Wang, Gong Li, Shizhong Yang. Safety and efficacy of radiotherapy combined with targeted neoadjuvant immunotherapy for intrahepatic cholangiocarcinoma [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2025, 14(01): 92-96.
[10]	Anti-Cancer Association China, Committee of Colorectal Cancer CACA the. CACA guidelines for holistic integrative management of anal cancer （2024 Edition） [J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2024, 13(06): 441-449.
[11]	Zhexue Wang, Junge Bai, Dedi Jiang, Yuegang Li, Ming Yang, Haipeng Chen, Zheng Liu. Factors influencing tumor regression grade and prognosis in locally advanced rectal cancer patients after neoadjuvant chemoradiotherapy [J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2024, 13(05): 368-374.
[12]	Yutian Tang, Yanzhi Wang, Yi Wang, Yimin Ren, Yanshan Zhang, Wenxue Zhao, Fang Wang, Wenyuan Yang. Safety analysis of high-frequency oscillatory ventilation to control respiratory movement in patients with thoracic and abdominal tumors treated with carbon ion precision therapy [J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2024, 10(04): 344-350.
[13]	Wei Duan, Fei Liu, Guangyuan Xu, Yuhao Cheng, Xing Chen. Effect of different dosimetric parameters of intensity modulated radiotherapy plans for esophageal cancer on the occurrence and severity of radiation pneumonia [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2024, 14(04): 320-324.
[14]	Haiqiang Chu, Yuanyou Yang, Gang Ren. Progress in research of radiotherapy-based combined therapy for pancreatic cancer [J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(04): 392-396.
[15]	Xinying Zheng, Huiyong Zhang, Xing Huang, Lei Qiu, Qingliang Fang, Zhenhui Lu, Lei Wang. Dual regulatory role of TGF-β in radiaotherapy [J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(03): 309-314.

Please choose a citation manager

Content to export