Research progress in degradable internal fixations

doi:10.3877/cma.j.issn.1674-1366.2018.05.009

Abstract

Abstract:

Internal fixation is often applied to promote fracture healing. Traditional non-degradable internal fixations often require secondary surgical removal because of tissue reaction and stress shielding effect. At present, the degradable internal fixation is a hot topic in the field of biological material research. Polylactic acid, as a more mature degradable internal fixation material, has been clinically applied. Because of its poor mechanical properties, it is widely used in non-load bearing parts of the cranio-facial region. Magnesium alloy is a research hotspot in the field of biodegradable internal fixation. Its main disadvantage is its fast degradation rate and hydrogen release. There are few studies on zinc alloy internal fixations, which have great development potential and are very likely to become a novel degradable internal fixation system. This article will review polylactic acid, magnesium alloys, and zinc alloys as internal fixation systems.

Key words: Biodegradable materials, Internal fixators, Polylactic acid, Magnesium alloys, Zinc alloys

Xiaoxi Shao, Xiang Wang, Fangfang Xu, Taiqiang Dai, Bin Liu, Yanpu Liu. Research progress in degradable internal fixations[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2018, 12(05): 317-321.

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