Evaluation of the therapeutic effect of fluoride varnish Duraphat for incipient carious lesions in permanent anterior teeth

doi:10.3877/cma.j.issn.1674-1366.2014.01.007

Abstract

Abstract:

Objective

To assess the therapeutic effect of fluoride varnish Duraphat on the performance of incipient carious lesions white spot lesions （WSL） in anterior teeth in vivo.

Methods

The sample included 120 children aged 7 to 13 years old， with a total of 146 active WSL in permanent anterior teeth. The children were randomly divided into 3 groups， according to the treatment received:Group A （fluoride varnish Duraphat + oral health instrument， n = 52）， Group B （oral health instrument，n=47） and Group C （control， n=47）. Maximum WSL dimensions （mesiodistal and incisogingival）were measured in millimeters by a previously calibrated single examiner using a periodontal probe. The oral hygiene was assessed by the plaque index.

Results

Wilcoxon test revealed a statistically significant difference （χ²=29.1，P＜0.001） between the initial size and final size in A group （1.53 vs. 0.88） and B group （1.56 vs. 1.47）. Pearson's chi-square test revealed statistically significant differences （χ²=42.5，P＜0.001） in the caries activity of the WSL among three groups.

Conclusions

The fluoride varnish Duraphat is effective to the incipient carious lesions in permanent anterior teeth.

Key words: Dental caries, Fluoride varnish, White spot lesions

Weini Xin, Qingfeng Xu. Evaluation of the therapeutic effect of fluoride varnish Duraphat for incipient carious lesions in permanent anterior teeth[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2014, 8(01): 33-36.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhkqyxyjzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-1366.2014.01.007

https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2014/V8/I01/33

Figures/Tables 3

References 10

［1］	Fejerskov O. Changing paradigms in concepts on dental caries:consequences for oral health care［J］. Caries Res， 2004，8（3）:182-191.
［2］	Torres SR， Nucci M， Milanos E， et al. Variations of salivary flow rates in Brazilian school children［J］. Braz Oral Res， 2006，20（1）:8-12.
［3］	Bretz WA， do Valle EV， Jacobson JJ， et al. Unstimulated salivary flow rates of young children ［J］. Oral Surg Oral Med Oral Pathol Oral Radiol Endod， 2001，91（5）:541-545.
［4］	Greene JC， Vermillion JR. The simplified oral hygiene index［J］. J Am Dent Assoc， 1964（68）:7-13.
［5］	Ismail AI， Sohn W， Tellez M， et al. The International Caries Detection and Assessment System（ICDAS）:an integrated system for measuring dental caries［J］. Community Dent Oral Epidemiol，2007，35（3）:170-178.
［6］	Castillo JL， Milgrom P， Kharasch E， et al. Evaluation of fluoride release from commercially available fluoride varnishes［J］. J Am Dent Assoc， 2001，132（10）:1389-1392.
［7］	Shen C， Autio-Gold J. Assessing fluoride concentration uniformity and fluoride release from three varnishes ［J］. J Am Dent Assoc， 2002，133（2）:176-182.
［8］	Du M， Cheng N， Tai B， et al. Randomized controlled trial on fluoride varnish application for treatment of white spot lesion after fixed orthodontic treatment ［J］. Clin Oral Investig， 2012，16（2）:463-468.
［9］	Stecksén-Blicks C， Renfors G， Oscarson ND， et al. Cariespreventive effectiveness of a fluoride varnish: a randomized controlled trial in adolescents with fixed orthodontic appliances［J］. Caries Res， 2007，41（6）:455-459.
［10］	Bishara SE， Ostby AW. White Spot Lesions: Formation，Prevention，and Treatment［J］. Seminars in Orthodontics， 2008，14（3）:174-182.

组别	龋活动性				总计
	治疗前		治疗后
	活动龋	静止龋	活动龋	静止龋
A组	52（100）	0（0）	20（38.5）	32（61.5）	52（100）
B组	47（100）	0（0）	38（80.9）	9（19.1）	47（100）
C组	47（100）	0（0）	45（95.7）	2（4.3）	47（100）
总计	146	0	103（70.5）	43（29.5）	146

组别	龋活动性				总计
	治疗前		治疗后
	活动龋	静止龋	活动龋	静止龋
A组	52（100）	0（0）	20（38.5）	32（61.5）	52（100）
B组	47（100）	0（0）	38（80.9）	9（19.1）	47（100）
C组	47（100）	0（0）	45（95.7）	2（4.3）	47（100）
总计	146	0	103（70.5）	43（29.5）	146

组别	龋活动性		P值
组别	治疗前	治疗后	P值
A组	1.53±0.66	0.88±0.53	＜0.001
B组	1.56±0.64	1.47±0.65	0.003
C组	1.57±0.73	1.60±0.71	0.59
P值	0.96	＜0.001

组别	龋活动性		P值
组别	治疗前	治疗后	P值
A组	1.53±0.66	0.88±0.53	＜0.001
B组	1.56±0.64	1.47±0.65	0.003
C组	1.57±0.73	1.60±0.71	0.59
P值	0.96	＜0.001

[1]	Jing Gong, Rong Wang. Structure of oral microflora and its effect on dental caries in 136 children aged 3-5 years old in Mianyang area [J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2024, 18(02): 100-107.
[2]	Yue Wang, Yuanmeng Yang, Teck-Ek Ho, Wen Meng, Xinyu Chen, Fei Li, Zhanmin Lu, Haixia Lu. Research progress on caries prevention and treatment based on oral microecology [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(06): 391-396.
[3]	Wuli Li, Chunhui Zhao, Cheng Sun, Guiting Zheng, Danjie Meng, Song Li. A clinical comparison of selective and complete caries removal techniques in the management of deep carious lesions proximal to the pulp in permanent teeth [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(04): 243-249.
[4]	Kun Liang, Zihan Zeng, Li Xie, Ke Yu, Xinnan Zhong, Yexian Chen, Kai Liu, Ruijie Huang. The impact of new tobacco products and traditional cigarettes on common oral diseases [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(02): 137-142.
[5]	Yuanjie Luo, Jingmei Yang, Shu Meng, Yibo Ao, Daonan Shen. Progress of research on quercetin against oral diseases [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(02): 117-122.
[6]	Peizhi Zhong, Yu Du. Research progress on diagnostic techniques of dental caries [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(02): 73-79.
[7]	Changying Ye, Jing Xie, Guicong Ding. Research advances in interim treatment of deciduous tooth caries [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(05): 365-370.
[8]	Xiangtao Wang, Aijuan Zhang, Wanchun Wang, Fangping Wang, Yingjie Xu, Yang Meng. Research and application of common bletilla rubber in oral diseases [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(05): 371-375.
[9]	Yishan Zhang, Dan Mo, Yiling Jiang, Sicheng Deng, Dongyan Wu, Hua Huang, Rongmin Qiu. Comparison of oral health behaviors of Zhuang and Han ethnic children in Baise, Guangxi [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(03): 172-179.
[10]	Dongmin Zhang, Zhen Li, Shanshan Liang, Minquan Du, Han Jiang. Effectiveness of adding cavity filling for first permanent molars to a school-based oral health program: A two-year field trial [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(03): 167-171.
[11]	Liangyue Pang, Huancai Lin. Application of artificial intelligence in the field of dental caries [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(03): 162-166.
[12]	Xuanyi Ma, Chuanhong Liu, Shishu Fang, Zhixin Song, Zuolin Jin, Qian Liu. An investigation on the morbidity and influencing factors of white spot lesions in orthodontic adolescent patients with clear aligner [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2022, 16(05): 275-280.
[13]	Ying Liao, Xianghui Xing. Dental caries, caries activity, oral health behaviors and their associations in children with visual impairment in Nanjing [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2021, 15(04): 222-227.
[14]	Xinhui Meng, Lijun Huo, Yayan Lei. Dynamic changes of dental plaque pH and research progress of detection techniques [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2021, 15(01): 54-57.
[15]	Xia Dong, Weiguo Yang, Minghua Wang. Relationship of serum vitamin D and Bifidobacterium levels with severe dental caries in children [J]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(05): 442-446.

Please choose a citation manager

Content to export