Application of blood extract in soft tissue aesthetics of anterior teeth

doi:10.3877/cma.j.issn.1674-1366.2019.03.010

Abstract

Abstract:

How to restore the soft tissue of the esthetic region of anterior teeth is a hotspot in stomatology. Blood extract has been widely used in soft and hard tissue increment technology in recent years due to its simple preparation technology, safe use and high concentration of growth factors. Depending on the preparation method, the blood extract can be divided into three generations: first-generation platelet rich plasma, second-generation platelet rich fibrin, and third-generation modified platelet rich fibrin, concentrated growth factor and injectable platelet-rich fibrin. In this paper, the history and preparation methods of various blood extracts are introduced, and the research and application progress in soft tissue aesthetics of anterior teeth are reviewed.

Key words: Platelet-rich plasma, Fibrin, Esthetics, dental, Therapy, soft tissue

Wenya Tang, Sai Ye, Changyong Yuan. Application of blood extract in soft tissue aesthetics of anterior teeth[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2019, 13(03): 188-192.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhkqyxyjzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-1366.2019.03.010

https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2019/V13/I03/188

References 41

[1]	Zigdon H, Machtei EE. The dimensions of keratinized mucosa around implants affect clinical and immunological parameters [J]. Clin Oral Implants Res, 2008, 19(4): 387-392. DOI: 10.1111/j.1600-0501.2007.01492.x.
[2]	Lang NP, Löe H. The relationship between the width of keratinized gingival and gingival health[J]. J Periodontol, 1972, 43(10): 623-627. DOI: 10.1902/jop.1972.43.10.623.
[3]	Choukroun J, Aalam AA, Miron RJ. Platelet Rich Fibrin "PRF" and Regenerative Medicine: 'The Low-Speed Concept’//In: Tatullo M.（eds）MSCs and Innovative Biomaterials in Dentisry. Stem Cell Biology and Regenerative Medicine[M]. Humana Press, Cham, 2017: 21-42. DOI: 10.1007/978-3-319-55645-1_2.
[4]	Isobe K, Watanebe T, Kawabata H, et al. Mechanical and degradation properties of advanced platelet-rich fibrin（APRF）, concentrated growth factors（CGF）, and platelet-poor plasma-derived fibrin（PPTF）[J]. Int J Implant Dent, 2017, 3(1): 17. DOI: 10.1186/s40729-017-0081-7.
[5]	Assoian RK, Grotendorst GR, Miller DM, et al. Cellular transformation by coordinated action of three peptide growth factors from human platelets[J]. Nature, 1984, 309(5971): 804-806. DOI: 10.1038/309804a0.
[6]	Landesberg R, Roy M, Glickman RS. Quantification of growth factor levels using a simplified method of platelet rich plasma gel preparation[J]. J Oral Maxillofac Surg, 2000, 58(3): 297-300. DOI: 10.1016/S0278-2391(00)90058-2.
[7]	Zhang CQ, Yuan T, Zeng BF. Experimental study of the effect of Platelet-rich plasma on osteogenesis in rabbit[J]. Chin Med J（Engl）, 2004, 117(12): 1853-1855.
[8]	Marx RE, Carlson ER, Eichstaedt RM, et al. Platelet-rich plasma: Growth factor enhancement for bone grafts[J]. Oral Surg Oral Med Oral Pathol Oral Radio Endod, 1998, 85(6): 638-646. DOI: 10.1016/s1079-2104(98)90029-4.
[9]	Choukroun J, Diss A, Simonpieri A, et al. Platelet-rich fibrin （PRF）: second-generation platelet concentrate. Part IV: clinical effects on tissue healing[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101(3): e56-e60. DOI: 10.1016/j.tripleo.2005.07.011.
[10]	Kökdere NN, Baykul T, Findik Y. The use of platelet-rich fibrin （PRF）and PRF-mixed particulated autogenous bone graft in the treatment of bone defects: An experimental and histomor phometrieal study[J]. Dent Res J（Isfahan）, 2015, 12(5): 418-424. DOI: 10.4103/1735-3327.166188.
[11]	Geeta IB, Galagali G, Kulkarni S, et al. A natural meliorate: revolutionary tissue engineering in endodontics[J]. J Clin Diagn Res, 2013, 7(11): 2644-2646. DOI: 10.7860/JCDR/2013/6915.3638.
[12]	Weibrieh G, Kleis WK, Hafner G. Growth factor levels in the platelet-rich plasma produced by 2 different methods: curasan-type PRP kit versus PCCS PRP system[J]. Int J Oral Maxillofac Implants, 2002, 17(2): 184-190. DOI: 10.1046/j.1365-2591.2002.00491.x.
[13]	Okuda K, Kawase T, Momose M, et al. Platelet rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodontally related cells in vitro[J]. J Periodontol, 2003, 74(6): 849-857.
[14]	Rodella LF, Favero G, Boninsegna R, et al. Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction[J]. Micros Res Tech, 2011, 74(8): 772-777. DOI: 10.1002/jemt.20968.
[15]	李永斌，孙迎春，韦荣智，等. 浓缩生长因子纤维蛋白与富血小板纤维蛋白体外降解的对比[J]. 中国组织工程研究，2017，21(14)：2234-2240. DOI：10.3969/j.issn.2095-4344.2017.14.017.
[16]	雷利红. 改良富血小板纤维蛋白与浓缩生长因子促牙周组织修复再生作用的比较研究[D]. 杭州：浙江大学，2018.
[17]	Marx RE, Carlson ER, Eichstaedt RM, et al. Platelet-rich plasma: growth factor enhancement for bone grafts[J]. Oral Surg Oral Med Oral Pathol Oral Radio Endod, 1998, 85(6): 638-646. DOI: 10.1016/s1079-2104(98)90029-4.
[18]	Kobayashi E, Fujioka KM, Sculean A, et al. Effects of platelet rich plasma（PRP）on human gingival fibroblast, osteoblast and periodontal ligament cell behaviour[J]. BMC Oral Health, 2017, 17(1): 91. DOI: 10.1186/s12903-017-0381-6.
[19]	施六霞，狄昌萍，徐艳，等. 富血小板血浆对人牙龈成纤维细胞增殖和迁移的影响[J]. 南京医科大学学报（自然科学版），2010(7)：942-945.
[20]	Tavassoli HS, Sattari M, Ghasemi T, et al. Effect of platelet-rich plasma concentrations on the proliferationof periodontal cells: An in vitro study[J]. Eur J Dent, 2016, 10(4): 469-674. DOI: 10.4103/1305-7456.195165.
[21]	Wang X, Zhang Y, Choukroun J, et al. Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with either Injectable-PRF or PRP[J]. Int J Mol Sci, 2017, 18(2): 331. DOI: 10.3390/ijms18020331.
[22]	Anh NP, Vu PTA. Effects of platelet-rich plasma on human gingival fibroblast proliferation and migration in vitro[J]. J Appl Oral Sci, 2018(26): e20180077. DOI: 10.1590/1678-7757-2018-0077.
[23]	Çetiner D, Kalabay PG, Özdemir B, et al. Efficiency of platelet-rich plasma on acellular dermal matrix application with coronally advanced flap in the treatment of multiple adjacent gingival recessions: A randomized controlled clinical trial[J]. J Dent Sci, 2018, 13(3): 198-206. DOI: 10.1016/j.jds.2017.11.002.
[24]	Samani MK, Saberi BV, Tabatabaei SMA, et al. The clinical evaluation of platelet-rich plasma on free gingival graft′s donor site wound healing[J]. Eur J Dent, 2017, 11(4): 447-454. DOI: 10.4103/ejd.ejd_76_17.
[25]	Srinivas BVV, Rupa N, Kumari KVH, et al. Root coverage using subepithelial connective tissue graft with platelet-rich plasma in the treatment of gingival recession: A clinical study[J]. J Pharm Bioallied Sci, 2015, 7(Suppl 2): S530-S538. DOI: 10.4103/0975-7406.163530.
[26]	倪宇昕. Choukroun′s富血小板纤维蛋白（PRF）促进牙龈软组织修复再生的实验研究[D]. 长春：吉林大学，2011.
[27]	焦志立. 两种富血小板纤维蛋白对人牙龈成纤维细胞的生长速度及质量影响的实验研究[D]. 泸州：西南医科大学，2017.
[28]	王佳. 富血小板纤维蛋白促进口腔软组织修复的研究[D]. 长春：吉林大学，2018.
[29]	Barone A, Ricci M, Romanos GE, et al. Buccal bone deficiency infresh extraction sockets: a prospective single cohort study[J]. Clin Oral Implants Res, 2015, 26(7): 823-830. DOI: 10.1111/c1r.12369.
[30]	Jain A, Jaiswal GR, Kumathalli K, et al. Comparative Evaluation of Platelet Rich Fibrin and Dehydrated Amniotic Membrane for the Treatment of Gingival Recession-A Clinical Study[J]. J Clin Diagn Res, 2017, 11(8): ZC24-ZC28. DOI: 10.7860/JCDR/2017/29599.10362.
[31]	Anilkumar K, Geetha A, Umasudhakar, et al. Platelet-rich-fibrin: A novel root coverage approach[J]. J Indian Soc Periodontol, 2009, 13(1): 50-54. DOI: 10.4103/0972-124X.51897.
[32]	Ahila E, Saravana Kumar R, Reddy VK, et al. Augmentation of Interdental Papilla with Platelet-rich Fibrin[J]. Contemp Clin Dent, 2018, 9(2): 213-217. DOI: 10.4103/ccd.ccd_812_17.
[33]	Fujioka KM, Miron RJ, Hernandez M, et al. Optimized Platelet Rich Fibrin With the Low Speed Concept: Growth Factor Release, Biocompatibility and Cellular Response[J]. J Periodontol, 2016, 88(1): 1-17. DOI: 10.1902/jop.2016.160443.
[34]	杨智超，王熙，兰文娟. 改良富血小板纤维蛋白在自体牙移植中的临床应用研究[J]. 内蒙古医学杂志，2018，50(10)：1153-1155. DOI：10.16096/J.cnki.nmgyxzz.2018.50.10.001.
[35]	张晓，董福生，任贵云，等. 富自体CGF纤维蛋白膜对人牙龈成纤维细胞黏附及增殖的影响[J]. 现代口腔医学杂志，2014，28(4)：197-201.
[36]	Yu B, Wang Z. Effect of concentrated growth factors on beagle periodontal ligament stem cells in vitro[J]. Mol Med Rep, 2014, 9(1): 235-242. DOI: 10.3892/mmr.2013.
[37]	Bozkurt Doğan Ş, Öngöz Dede F, Ballı U, et al. Concentrated growth factor in the treatment of adjacent multiple gingival recessions: a split-mouth randomized clinical trial[J]. J Clin Periodontol, 2015, 42(9): 868-875. DOI: 10.1111/jcpe.12444.
[38]	孙丽超，陈学军，郭海波. CGF复合骨诱导材料在前牙美学区种植的临床应用[J]. 全科口腔医学电子杂志，2018，5(15)：24，26.
[39]	杨立明，陈淑萍，李恩洪. 浓缩生长因子（CGF）在即刻种植修复应用中的牙龈美学研究[J]. 中国美容医学，2015，24(1)：63-65.
[40]	Miron RJ, Fujioka-Kobayashi M, Hernandez M, et al. Injectable platelet rich fibrin（i-PRF）: opportunities in regenerative dentistry？[J]. Clin Oral Invest, 2017, 21(8): 2619-2627. DOI: 10.1007/s00784-017-2063-9.
[41]	Kour P, Pushpa SP, Ancia MV, et al. Comparative Evaluation of Antimicrobial Efficacy of Platelet-rich Plasma, Platelet-rich Fibrin, and Injectable Platelet-rich Fibrin on the Standard Strains of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans[J]. Contemp Clin Dent, 2018, 9(2): 325-330. DOI: 10.4103/ccd.ccd_367_18.

Please choose a citation manager

Content to export