The application prospects of graphene in dental implantation

doi:10.3877/cma.j.issn.1674-1366.2016.02.014

Abstract

Abstract:

Graphene, honored as ′black gold′, is worthy of ′the king of new materials′ in 21st century. Due to its unique structure and excellent properties, it is expected to be widely used in biomedical fields such as tissue engineering, drug delivery, gene loading and biological imaging. Graphene has vast application prospects in the field of oral medicine. The properties including biocompatibility, cytotoxicity, antibacterial activity, promoting osteogenic differentiation and the unique mechanism are discussed. This review elaborates the research on dental implantation.

Key words: Graphene, Properties, Applications, Dental implantation

Changbo Wei, Dongsheng Yu. The application prospects of graphene in dental implantation[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2016, 10(02): 151-154.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhkqyxyjzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-1366.2016.02.014

https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2016/V10/I02/151

References 48

[1]	Novoselov KS, Geim AK, Morozov SV，et al. Electric field effect in atomically thin carbon films[J]. Science，2004，306(5696):666-669.
[2]	Singh V, Joung D, Zhai L，et al. Graphene based materials：Past，present and future[J]. Prog Mater Sci，2011，56(8):1178-1271.
[3]	Lee C, Wei X, Kysar JW，et al. Measurement of the elastic properties and intrinsic strength of monolayer graphene[J]. Science，2008，321(5887):385-388.
[4]	Berber S, Kwon YK, Tomanek D. Unusually high thermal conductivity of carbon nanotubes[J]. Phys Rev Lett，2000，84(20):4613-4616.
[5]	Freitag M, Steiner M, Martin Y，et al. Energy dissipation in graphene field-effect transistors[J]. Nano Lett，2009，9(5):1883-1888.
[6]	Kim S, Ihm J, Choi HJ，et al. Origin of anomalous electronic structures of epitaxial graphene on silicon carbide[J]. Phys Rev Lett，2008，100(17):176802.
[7]	Nair RR, Blake P, Grigorenko AN，et al. Fine structure constant defines visual transparency of graphene[J]. Science，2008，320(5881):1308.
[8]	Zhang L, Zhang F, Yang X，et al. Porous 3D graphene-based bulk materials with exceptional high surface area and excellent conductivity for supercapacitors[J]. Sci Rep，2013，3:1408.
[9]	Geim AK, Novoselov KS. The rise of graphene[J]. Nat Mater，2007，6(3):183-191.
[10]	Zhang Y, Ali SF, Dervishi E，et al. Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells[J]. ACS Nano，2010，4(6):3181-3186.
[11]	Rosa V, Della BA, Cavalcanti BN，et al. Tissue engineering：from research to dental clinics[J]. Dent Mater，2012，28(4):341-348.
[12]	Lee WC, Lim CH, Shi H，et al. Origin of enhanced stem cell growth and differentiation on graphene and graphene oxide[J]. ACS Nano，2011，5(9):7334-7341.
[13]	Elkhenany H, Amelse L, Lafont A，et al. Graphene supports in vitro proliferation and osteogenic differentiation of goat adult mesenchymal stem cells：potential for bone tissue engineering[J]. J Appl Toxicol，2015，35(4):367-374.
[14]	Sasidharan A, Panchakarla LS, Chandran P，et al. Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene[J]. Nanoscale，2011，3(6):2461-2464.
[15]	Yang K, Wan J, Zhang S，et al. In vivo pharmacokinetics，long-term biodistribution，and toxicology of PEGylated graphene in mice[J]. ACS Nano，2011，5(1):516-522.
[16]	Hu W, Peng C, Luo W，et al. Graphene-based antibacterial paper[J]. ACS Nano，2010，4(7):4317-4323.
[17]	Liu S, Zeng TH, Hofmann M，et al. Antibacterial activity of graphite，graphite oxide，graphene oxide，and reduced graphene oxide：membrane and oxidative stress[J]. ACS Nano，2011，5(9):6971-6980.
[18]	Tu Y, Lv M, Xiu P，et al. Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets[J]. Nat Nanotechnol，2013，8(12):968.
[19]	Kulshrestha S, Khan S, Meena R，et al. A graphene/zinc oxide nanocomposite film protects dental implant surfaces against cariogenic Streptococcus mutans[J]. Biofouling，2014，30(10):1281-1294.
[20]	Mombelli A. Microbiology and antimicrobial therapy of peri-implantitis[J]. Periodontol 2000，2002(28):177-189.
[21]	Quirynen M, De Soete M, van Steenberghe D. Infectious risks for oral implants：a review of the literature[J]. Clin Oral Implants Res，2002，13(1):1-19.
[22]	Branemark PI. Osseointegration and its experimental background[J]. J Prosthet Dent，1983，50(3):399-410.
[23]	Nayak TR, Andersen H, Makam VS，et al. Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells[J]. ACS Nano，2011，5(6):4670-4678.
[24]	Rosa V, Zhang Z, Grande RH，et al. Dental pulp tissue engineering in full-length human root canals[J]. J Dent Res，2013，92(11):970-975.
[25]	Qi W, Yuan W, Yan J，et al. Growth and accelerated differentiation of mesenchymal stem cells on graphene oxide/poly-L-lysine composite films[J]. J Mater Chem B，2014，2(33):5461-5467.
[26]	Kalbacova M, Broz A, Kong J，et al. Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells[J]. Carbon，2010，48(15):4323-4329.
[27]	Alzhavan O, Ghaderi E, Shahsavar M. Graphene nanogrids for selective and fast osteogenic differentiation of human mesenchymal stem cells[J]. Carbon，2013(59):200-211.
[28]	Ryoo HM, Hoffmann HM, Beumer T，et al. Stage-specific expression of Dlx-5 during osteoblast differentiation：Involvement in regulation of osteocalcin gene expression[J]. Mol Endocrinol，1997，11(11):1681-1694.
[29]	Kim J, Kim Y, Kim Y，et al. Graphene-incorporated chitosan substrata for adhesion and differentiation of human mesenchymal stem cells[J]. J Mater Chem B，2013，1(7):933-938.
[30]	Xie Y, Li H, Zhang C，et al. Graphene-reinforced calcium silicate coatings for load-bearing implants[J]. Biomed Mater，2014，9(2):025009.
[31]	Tatavarty R, Ding H, Lu G，et al. Synergistic acceleration in the osteogenesis of human mesenchymal stem cells by graphene oxide-calcium phosphate nanocomposites[J]. Chem Commun，2014，50(62):8484-8487.
[32]	Gao C, Liu T, Shuai C，et al. Enhancement mechanisms of graphene in nano-58S bioactive glass scaffold：mechanical and biological performance[J]. Sci Rep，2014，4:4712.
[33]	Porwal H, Grasso S, Cordero-Arias L，et al. Processing and bioactivity of 45S5 Bioglass^®-graphene nanoplatelets composites[J]. J Mater Sci Mater Med，2014，25(6):1403-1413.
[34]	Loh KP, Bao Q, Ang PK，et al. The chemistry of graphene[J]. J Mater Chem，2010，20(12):2277-2289.
[35]	Pei S, Cheng H. The reduction of graphene oxide[J]. Carbon，2012，50(9):3210-3228.
[36]	Jiayu L, Yu-Shi H, Chi C，et al. Self-supporting graphene hydrogel film as an experimental platform to evaluate the potential of graphene for bone regeneration[J]. Adv Funct Mater，2013，23(28):3494-3502.
[37]	Kang SW, La WG, Kang JM，et al. Bone morphogenetic protein-2 enhances bone regeneration mediated by transplantation of osteogenically undifferentiated bone marrow-derived mesenchymal stem cells[J]. Biotechnol Lett，2008，30(7):1163-1168.
[38]	Depan D, Girase B, Shah JS，et al. Structure-process-property relationship of the polar graphene oxide-mediated cellular response and stimulated growth of osteoblasts on hybrid chitosan network structure nanocomposite scaffolds[J]. Acta Biomater，2011，7(9):3432-3445.
[39]	Li M, Liu Q, Jia Z，et al. Graphene oxide/hydroxyapatite composite coatings fabricated by electrophoretic nanotechnology for biological applications[J]. Carbon，2014，67:185-197.
[40]	La WG, Park S, Yoon HH，et al. Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide[J]. Small，2013，9(23):4051-4060.
[41]	La WG, Kang SW, Yang HS，et al. The efficacy of bone morphogenetic protein-2 depends on its mode of delivery[J]. Artif Organs，2010，34(12):1150-1153.
[42]	Jemt T, Lekholm U. Oral implant treatment in posterior partially edentulous jaws：a 5-year follow-up report[J]. Int J Oral Maxillofac Implants，1993，8(6):635-640.
[43]	Kallus T, Bessing C. Loose gold screws frequently occur in full-arch fixed prostheses supported by osseointegrated implants after 5 years.[J]. Int J Oral Maxillofac Implants，1994，9(2):169-178.
[44]	Kim KH, Choi MY, Kishi T. Fracture analysis of cast pure Ti and Ti-6Al-4V alloy for dental use[J]. Biomed Mater Eng，1997，7(4):271-276.
[45]	Dawson JI, Oreffo ROC. Bridging the regeneration gap：Stem cells，biomaterials and clinical translation in bone tissue engineering[J]. Arch Biochem Biophys，2008，473(2):124-131.
[46]	Yavari F, Rafiee MA, Rafiee J，et al. Dramatic Increase in Fatigue Life in Hierarchical Graphene Composites[J]. ACS Appl Mater Interfaces，2010，2(10):2738-2743.
[47]	Wan C, Frydrych M, Chen B. Strong and bioactive gelatin-graphene oxide nanocomposites[J]. Soft Matter，2011，7(13):6159-6166.
[48]	Bortz DR, Garcia Heras E, Martin-Gullon I. Impressive Fatigue Life and Fracture Toughness Improvements in Graphene Oxide/Epoxy Composites[J]. Macromolecules，2012，45(1):238-245.

Please choose a citation manager

Content to export