Abstract:
Objective
To evaluate the effect of Suction Drainage （SD） in the treatment of large odontogenic keratocysts.
Methods
Fifteen patients with large odontogenic keratocysts were recruited for the study. Clinical parameters， radiographic assessment and histopathological observation were employed to evaluate the treatment effects before and after the usage of SD. Ki-67 and PCNA were performed to detect the proliferation activity of cyst epithelium cells by immunohisto-chemistry.
Result
After the usage of SD， the facial deformity of all the patients disappeared within 1 ～2 months； the size of cyst decreased about 52.8% and 89.6% at the 2nd and the 6th month respectively.Histopathological observation showed that the average thickness of new bone was 2.6 mm at the 2nd month and 4.84 mm at the 6th month. Significant decrease of Ki-67 was also found after the treatment.
Conclusion
Suction drainage may rapidly correct the facial deformity and promote the formation of new bone adjacent to the cyst lesion.
Key words:
Odontogenic keratocysts,
Suction drainage,
Immunochemistry
Zi-qiang JIANG, Yi-fang ZHAO. The primary study of suction drainage in the treatment for large odontogenic keratocysts[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2007, 01(01): 47-50.