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中华口腔医学研究杂志(电子版) ›› 2010, Vol. 4 ›› Issue (06) : 597 -603. doi: 10.3877/cma.j.issn.1674-1366.2010.06.010

临床研究

预成钛网联合自体髂骨及松质骨游离移植二期修复单侧下颌骨缺损
侯劲松1, 汪淼1, 唐海阔1, 陶谦1, 潘朝斌2, 陈沐1, 王成1, 廖贵清1, 杨小平1, 黄洪章1,()   
  1. 1.510055 广州,中山大学光华口腔医学院·附属口腔医院·口腔医学研究所
    2.中山大学孙逸仙纪念医院口腔颌面外科
  • 收稿日期:2010-07-04 出版日期:2010-12-01
  • 通信作者: 黄洪章
  • 基金资助:
    2007~2009年度卫生部部属(管)医院临床学科重点项目(应用CAD/CAM 修复颌骨缺损与重建咬合功能)

Secondary reconstruction of unilateral mandible defect using CAD/CAM-prefabricated titanium mesh combined with autogenous iliac cancellous bone grafts

Jin-song HOU1, Miao WANG1, Hai-kuo TANG1, Qian TAO1, Chao-bin PAN1, Mu CHEN1, Cheng WANG1, Gui-qing LIAO1, Xiao-ping YANG1, Hong-zhang HUANG1,()   

  1. 1.Guanghua School of Stomatology, Institute of Stomatological Research, Sun Yat-sen University, Guangzhou 510055, China
  • Received:2010-07-04 Published:2010-12-01
  • Corresponding author: Hong-zhang HUANG
引用本文:

侯劲松, 汪淼, 唐海阔, 陶谦, 潘朝斌, 陈沐, 王成, 廖贵清, 杨小平, 黄洪章. 预成钛网联合自体髂骨及松质骨游离移植二期修复单侧下颌骨缺损[J/OL]. 中华口腔医学研究杂志(电子版), 2010, 4(06): 597-603.

Jin-song HOU, Miao WANG, Hai-kuo TANG, Qian TAO, Chao-bin PAN, Mu CHEN, Cheng WANG, Gui-qing LIAO, Xiao-ping YANG, Hong-zhang HUANG. Secondary reconstruction of unilateral mandible defect using CAD/CAM-prefabricated titanium mesh combined with autogenous iliac cancellous bone grafts[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2010, 4(06): 597-603.

目的

探讨已形成下颌偏斜、咬合错乱的单侧下颌骨缺损二期修复的有效方法。

方法

对单侧下颌骨部分切除造成下颌偏斜和咬合错乱的9 例患者行术前CT 扫描,计算机辅助设计与制作(CAD/CAM)快速原型技术重建颅颌面骨三维数字模型,并以健侧下颌骨为模板,镜像形成缺损侧下颌骨。激光树脂成型机打印下颌骨实体模型,在实体模型上按缺损范围设计钛网,使预成钛网与缺损下颌骨外形一致。数控成型机制备钛网,切取髂骨及其松质骨,联合预成钛网植入完成下颌骨缺损二期修复。

结果

预成钛网联合9 例髂骨松质骨移植均获成功,创口愈合良好,下颌骨外形恢复满意,颜面偏斜得到有效矫正,咬合关系恢复正常。

结论

术前应用CAD/CAM 快速原型技术制备预成钛网、联合自体松质骨游离移植二期修复单侧下颌骨缺损,不仅可以缩短手术时间,还能最大限度地重建下颌骨解剖外形、恢复患者颜面外观和咬合功能。

Objective

The purpose of this clinical study was to explore the effective method of secondary reconstruct of unilateral mandible defects that caused mandible deviation and occlusal disorder.

Methods

Nine patients with unilateral mandible defects, with obvious mandible deviation and occlusal disorder, were included.The virtual models of craniomaxillofacial bone were created by 3-demensional CT can.Mandible of the unaffected side was copied to the affected side by reflection method of computer-aided design system (CAD).Solid physical models of the rehabilitated mandible were created by computer-aided manufacture (CAM)and rapid prototyping technique.The titanium mesh was prefabricated accurately on the solid model.9 iliac cancellous bone grafts were harvested and used to repair unilateral mandible defects in combined with titanium mesh cages.

Results

All grafts survived entirety without complication and the contours of mandibles were satisfying.Significant improvement of the facial symmetry and occlusion in 9 patients were observed after treatment.

Conclusions

Satisfactory aesthetic and functional results could be achieved by CAD/CAM combined with autogenous cancellous bone grafts for secondary reconstruction of unilateral mandible defect.

图1 数字化颅颌面骨的三维重建 A:右侧观; B:正面观
图2 下颌骨缺损的数字化模拟修复 A:健侧下颌骨; B:镜像形成的对侧下颌骨; C:模拟重建后完整的下颌骨
图3 下颌骨实体模型打印和实际缺损区的确定 A:下颌骨缺损实体模型; B:模拟重建后的下颌骨实体模型; C:缺损范围的确定和预成钛网设计
图4 冲压成型的预成钛网
图5 预成钛网及髂骨松质骨植入下颌骨缺损区
图6 患者手术前后的正面观 A:术前; B:术后
图7 患者手术前后的咬合关系 A:术前; B:术后
图8 患者术后2 个月的全景片 透过钛网孔隙可见移植骨与下颌骨断端间有模糊的线形低密度影
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