Abstract:

Pleomorphic adenoma is the most common benign tumor in salivary gland and its metastasis rarely occurs. The local or distant metastatic tumor of benign pleomorphic adenoma is clinically and histopathologically called metastatic pleomorphic adenoma (MPA) . A rare case of pleomorphic adenoma was reported in this article. This patient suffered from a pleomorphic adenoma originally in the left submandibular gland, which was treated by surgical removal two years ago. Subsequently, a local recurrence of the pleomorphic adenoma with multiple bilateral pulmonary metastasis was found, so that the submaxillary area and lung masses were surgically exenterated. Upon the review of literature, the clinicopathological and metastatic features, as well as the key therapeutic strategies of this disease were discussed in this article.

Key words: Pleomorphic adenoma, Neoplasm metastasis, Lung neoplasms, Submandibular gland