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Chinese Journal of Stomatological Research(Electronic Edition) ›› 2020, Vol. 14 ›› Issue (05): 334-338. doi: 10.3877/cma.j.issn.1674-1366.2020.05.011

Special Issue:

• Review • Previous Articles    

Research progress on the osteogenesis of bone biomaterials under oxidative stress

Jingyan Huang1, Yan Wang1,()   

  1. 1. Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangdong Provincal Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2020-02-07 Online:2020-10-01 Published:2020-10-01
  • Contact: Yan Wang
  • About author:
    Corresponding author: Wang Yan, Email:
  • Supported by:
    Guangdong Basic and Applied Basic Research Foundation(2019A1515011842); Guangdong Financial Fund for High-Caliber Hospital Construction(174-2018-XMZC-0001-03-0125/D-09)

Abstract:

The osteogenesis of bone biomaterials tends to be compromised among the population suffering from aging and aging related diseases as well as diabetes. It has been shown that such diseases are closely related to oxidative stress. In recent years, the application of bone biomaterials under oxidative stress microenvironment comes into focus. Upon reviewing the related publications, the osteogenesis of bone biomaterials, or the interplay between the biomaterials and the oxidative stress microenvironment was summarized. This review was expected to deepen the understanding on the osteogenic mechanism of bone biomaterials in pathological status, and play a reference role on the selection of appropriate bone biomaterials clinically and the design of novel universal biomaterials.

Key words: Oxidative stress, Bone biomaterials, Osteogenesis

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