Retrospective analysis of clinical effect of iodoform-iodoglycerin-gelatin sponge in the treatment of dry socket

doi:10.3877/cma.j.issn.1674-1366.2024.06.006

Abstract

Abstract:

Objective

To observe and evaluate the clinical effect of using iodoform-iodoglyceringelatin sponge to treat dry socket without local anesthetic debridement.

Methods

A total of 32 patients with dry socket who were treated at the Third Affiliated Hospital of Sun Yat-sen University from July 2020 to July 2023 were recruited，and they were divided into an observation group and a control group，with 16 patients in each. For the observation group，patients were treated without local anesthetic debridement，and the tooth socket was flushed and filled with iodoform-iodoglycerin-gelatin sponge. For the control group，the paitents were treated according to the traditional method of dry socket，where the tooth socket was debrided under local anesthesia，and the iodophor gauze was filled after hydrogen peroxide and saline cleaning.The pain degree（visual analogue scale）on the first，third，and seventh day after treatment，and the growth of granulation tissue in the tooth socket and the pain sensation of the bone wall on the seventh day were evaluated in the two groups. The pain score and treatment effectiveness of the two groups were statistically analyzed by t-test and Chi-square test，and the test level α = 0.05.

Results

For the observation group，the VAS pain scores before treatment，on the first，third，and seventh day after treatment were 8.50±0.89，7.19±0.98，3.44±1.15，and 1.13±0.74，respectively.For the control group，the VAS pain scores before treatment，on the first，third，and seventh day after treatment were 8.44±0.96，6.69±1.20，3.16±0.81，and 1.06±0.83，respectively.Compared with the first day，the VAS values of the observation and the control groups both showed significant decrease on the third days after treatment（t_observation_group = 13.88，P_observation_group＜0.001，t_control_group = 16.91，P_control_group＜0.001）. There was no statistical significance in pain scores between the two groups at each time point（t₀_d=0.19，P₀_d=0.85；t₃_d=0.96，P₃_d=0.35；t₇_d=0.25，P₇_d=0.80）.The treatment effective rate of the observation group（93.75%）and the control group（100%）showed no statistically significant difference（χ²=1.032，P=0.31）.

Conclusions

The use of iodoform-iodoglycerin-gelatin sponge for local treatment of dry socket could significantly relieve the pain symptoms of patients and promote the healing of the tooth socket，which would be an effective and relatively minimally invasive method for treating dry socket.

Key words: Dry socket, Gelatin sponge，absorbable, Iodoform, Iodoglycerin

Shiwei Luo, Weiguo Li, Guorong Dai. Retrospective analysis of clinical effect of iodoform-iodoglycerin-gelatin sponge in the treatment of dry socket[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(06): 380-384.

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References 29

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组别	例数	治疗前	治疗后第1天	治疗后第3天	治疗后第7天
观察组	16	8.50±0.89	7.19±0.98	3.44±1.15^a	1.13±0.74^ab
对照组	16	8.44±0.96	6.69±1.20	3.16±0.81^a	1.06±0.83^a
t值		0.19	1.29	0.96	0.25
P值		0.85	0.21	0.35	0.80

组别	例数	治疗前	治疗后第1天	治疗后第3天	治疗后第7天
观察组	16	8.50±0.89	7.19±0.98	3.44±1.15^a	1.13±0.74^ab
对照组	16	8.44±0.96	6.69±1.20	3.16±0.81^a	1.06±0.83^a
t值		0.19	1.29	0.96	0.25
P值		0.85	0.21	0.35	0.80

组别	例数	显效	有效	无效	治疗有效率
观察组	16	9（56.25）	6（37.50）	1（6.25）	15（93.75）
对照组	16	12（75.00）	4（25.00）	0（0）	16（100.00）

组别	例数	显效	有效	无效	治疗有效率
观察组	16	9（56.25）	6（37.50）	1（6.25）	15（93.75）
对照组	16	12（75.00）	4（25.00）	0（0）	16（100.00）

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