The progress on the regulation effect of Fibulin-7 in dental development

doi:10.3877/cma.j.issn.1674-1366.2016.06.013

Abstract

Abstract:

Fibulin-7, known as TM14, has been identified as a new member of the Fibulin family proteins, and was firstly constructed and screened by differential hybridization using cDNA microarrays of dental germs. It is a 440-amino acid protein that has a calculated molecular weight of 48 000. As the Fibulin family proteins are expressed in basement membranes, elastic fibers and other matrices, they had been found in association with ECM and can play important parts in angiogenesis and organ development, which are involved in the process of forming and stabilizing the organization of ECM structures. Fibulin-7 mRNA is expressed not only in developing teeth, hair follicles and cartilage, but also in spongiotrophoblast cells of embryo, and extraembryonic tissues of the placenta. During odontoblast differentiation, Fibulin-7 interacts with Fibulin-1, fibronectin, and dentin sialophosphoprotein, and may serve as a cell adhesion molecule to anchor dental mesenchymal cells and odontoblasts in the dentin matrix. Fibulin-7 gene is located in human chromosome 2q13, and its deletion in zebrafish leads to congenital heart defects and craniofacial malformations. The purpose of this review is to summarize the effect of Fibulin-7 in dental development.

Key words: Fibulin-7, Fibulin family proteins, Dental development, Maxillofacial development

Ningjuan Ou-Yang, Jiewen Dai, Guofang Shen. The progress on the regulation effect of Fibulin-7 in dental development[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2016, 10(01): 68-71.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhkqyxyjzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-1366.2016.06.013

https://zhkqyxyjzz.cma-cmc.com.cn/EN/Y2016/V10/I01/68

References 40

[1]	Timpl R, Sasaki T, Kostka G，et al. Fibulins：a versatile family of extracellular matrix proteins[J]. Nat Rev Mol Cell Biol，2003，4(6):479-489.
[2]	Argraves WS, Greene LM, Cooley MA，et al. Fibulins：physiological and disease perspectives[J]. EMBO Rep，2003，4(12):1127-1131.
[3]	Argraves WS, Dickerson K, Burgess WH，et al. Fibulin，a novel protein that interacts with the fibronectin receptor beta subunit cytoplasmic domain[J]. Cell，1989，58(4):623-629.
[4]	Gallagher WM, Currid CA, Whelan LC. Fibulins and cancer：friend or foe？[J]. Trends Mol Med，2005，11(7):336-340.
[5]	Kobayashi N, Kostka G, Garbe JH，et al. A comparative analysis of the fibulin protein family. Biochemical characterization，binding interactions，and tissue localization[J]. J Biol Chem，2007，282(16):11805-11816.
[6]	Harikrishnan K, Cooley MA, Sugi Y，et al. Fibulin-1 suppresses endothelial to mesenchymal transition in the proximal outflow tract[J]. Mech Dev，2015(136):123-32.
[7]	Zhang HY, Timpl R, Sasaki T，et al. Fibulin-1 and fibulin-2 expression during organogenesis in the developing mouse embryo[J]. Dev Dyn，1996，205(3):348-364.
[8]	Miosge N, Götz W, Sasaki T，et al. The extracellular matrix proteins fibulin-1 and fibulin-2 in the early human embryo[J]. Histochem J，1996，28(2):109-116.
[9]	McLaughlin PJ, Bakall B, Choi J，et al. Lack of fibulin-3 causes early aging and herniation，but not macular degeneration in mice[J]. Hum Mol Genet，2007，16(24):3059-3070.
[10]	Yamashiro Y, Papke CL, Kim J，et al. Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice[J]. Sci Signal，2015，8(399):ra105.
[11]	McLaughlin PJ, Chen Q, Horiguchi M，et al. Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice[J]. Mol Cell Biol，2006，26(5):1700-1709.
[12]	Guo J, Cheng C, Chen CS，et al. Overexpression of fibulin-5 attenuates ischemia/reperfusion injury after middle cerebral artery occlusion in rats[J/OL]. Mol Neurobiol，2015[2016-01-07]. published online ahead of print May 6，2015]. URL
[13]	Westcot SE, Hatzold J, Urban MD，et al. Protein-trap insertional mutagenesis uncovers new genes involved in zebrafish skin development，including a neuregulin 2a-based erbb signaling pathway required during median fin fold morphogenesis[J]. PLoS One，2015，10(6):e0130688.
[14]	Tran H, VanDusen WJ, Argraves WS. The self-association and fibronectin-binding sites of fibulin-1 map to calcium-binding epidermal growth factor-like domains[J]. J Biol Chem，1997，272(36):22600-22606.
[15]	Adam S, Göhring W, Wiedemann H，et al. Binding of fibulin-1 to nidogen depends on its C-terminal globular domain and a specific array of calcium-binding epidermal growth factor-like （EG）modules[J]. J Mol Biol，1997，272(2):226-236.
[16]	de Vega S, Iwamoto T, Yamada Y. Fibulins：multiple roles in matrix structures and tissue functions[J]. Cell Mol Life Sci，2009，66(11-12):1890-1902.
[17]	Reid KB, Day AJ. Structure-function relationships of the complement components[J]. Immunol Today，1989，10(6):177-180.
[18]	de Vega S, Iwamoto T, Nakamura T，et al. TM14 is a new member of the fibulin family（fibulin-7）that interacts with extracellular matrix molecules and is active for cell binding[J]. J Biol Chem，2007，282(42):30878-30888.
[19]	Ehlermann J, Weber S, Pfisterer P，et al. Cloning，expression and characterization of the murine Efemp1，a gene mutated in Doyne-Honeycomb retinal dystrophy[J]. Gene Expr Patterns，2003，3(4):441-447.
[20]	Olin AI, Mörgelin M, Sasaki T，et al. The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding[J]. J Biol Chem，2001，276(2):1253-1261.
[21]	Singh U, Sun T, Larsson T，et al. Expression and functional analysis of fibulin-1（Fbln1）during normal and abnormal placental development of the mouse[J]. Placenta，2006，27(9-10):1014-1021.
[22]	Sreenath T, Thyagarajan T, Hall B，et al. Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta typeⅢ[J]. J Biol Chem，2003，278(27):24874-24880.
[23]	de Vega S, Hozumi K, Suzuki N，et al. Identification of peptides derived from the C-terminal domain of Fibulin-7 active for endothelial cell adhesion and tube formation disruption[J/OL]. Biopolymers，2015[2016-01-07]. published online ahead of print October 22，2015]. URL
[24]	Ido H, Harada K, Futaki S，et al. Molecular dissection of the alpha-dystroglycan- and integrin-binding sites within the globular domain of human laminin-10[J]. J Biol Chem，2004，279(12):10946-10954.
[25]	Kusano Y, Yoshitomi Y, Munesue S，et al. Cooperation of syndecan-2 and syndecan-4 among cell surface heparan sulfate proteoglycans in the actin cytoskeletal organization of Lewis lung carcinoma cells[J]. J Biochem，2004，135(1):129-137.
[26]	Hozumi K, Suzuki N, Nielsen PK，et al. Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1[J]. J Biol Chem，2006，281(43):32929-32940.
[27]	Mostafavi-Pour Z, Askari JA, Parkinson SJ，et al. Integrin-specific signaling pathways controlling focal adhesion formation and cell migration[J]. J Cell Biol，2003，161(1):155-167.
[28]	Soemedi R, Wilson IJ, Bentham J，et al. Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease[J]. Am J Hum Genet，2012，91(3):489-501.
[29]	Cooley MA, Fresco VM, Dorlon ME，et al. Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage，suppression of ErbB2 and Erk1/2 activation，and to attenuate trabecular cardiomyocyte proliferation[J]. Dev Dyn，2012，241(2):303-314.
[30]	Hanada K, Vermeij M, Garinis GA，et al. Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice[J]. Circ Res，2007，100(5):738-746.
[31]	Wang X, LeMaire SA, Chen L，et al. Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection[J]. Surgery，2005，138(2):352-359.
[32]	Paapstel K, Zilmer M, Eha J，et al. Association between fibulin-1 and aortic augmentation index in male patients with peripheral arterial disease[J]. Eur J Vasc Endovasc Surg，2016，51(1):76-82.
[33]	Lee YH, Albig AR, Regner M，et al. Fibulin-5 initiates epithelial-mesenchymal transition（EMT）and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP-dependent mechanism[J]. Carcinogenesis，2008，29(12):2243-2251.
[34]	Schiemann WP, Blobe GC, Kalume DE，et al. Context-specific effects of fibulin-5（DANCE/EVEC）on cell proliferation，motility，and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades[J]. J Biol Chem，2002，277(30):27367-27377.
[35]	Zavadil J, Cermak L, Soto-Nieves N，et al. Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition[J]. EMBO J，2004，23(5):1155-1165.
[36]	Eldadah ZA, Hamosh A, Biery NJ，et al. Familial Tetralogy of Fallot caused by mutation in the jagged1 gene[J]. Hum Mol Genet，2001，10(2):163-169.
[37]	Rudd MK, Keene J, Bunke B，et al. Segmental duplications mediate novel，clinically relevant chromosome rearrangements[J]. Hum Mol Genet，2009，18(16):2957-2962.
[38]	Riley KN, Catalano LM, Bernat JA，et al. Recurrent deletions and duplications of chromosome 2q11.2 and 2q13 are associated with variable outcomes[J]. Am J Med Genet A，2015，167(11):2664-2673.
[39]	Hladilkova E, Barøy T, Fannemel M，et al. A recurrent deletion on chromosome 2q13 is associated with developmental delay and mild facial dysmorphisms[J]. Mol Cytogenet，2015(8):57.
[40]	Russell MW, Raeker MO, Geisler SB，et al. Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations[J]. Hum Mol Genet，2014，23(16):4272-4284.

Please choose a citation manager

Content to export