To investigate the antibiotic resistance of clinical bacteria isolated from maxillofacial surgery patients in stomatology hospital in an effort to offer basis for the rational use of antibiotics and the target monitoring of multi-drug resistant bacteria.

All of the bacterial susceptibility results were collected according to maxillofacial surgery patients in stomatology hospital from 2012 to 2014. The data were analyzed by Chi-squared test.

There were totally 689 strains of bacteria isolated. Gram positive and gram negative bacteria accounted for about 31.8% (219/689) and 68.2% (470/689) , respectively. The most of top three bacteria were Pseudomonas aeruginosa (96 strains) , Klebsiella pneumonia (67 strains) and Streptococcus viridians (51 strains) . The drug resistance rate of Pseudomonas aeruginosa to cephalosporins was lower than 10%. The drug resistance rate of Pseudomonas aeruginosa to meropenem (χ² = 2.675, P = 0.229) and aztreonam (χ² = 0.469, P = 0.791) were less than 8%. Among three years, 90.0%, 66.7%, 95.2% Staphylococcus aureus were resistance to penicillihe (χ² = 7.212, P = 0.024) , respectively. More than 60% Enterobacter cloacae isolated from 2012 to 2013 were resistance to tetracycline, sulfonamide and cephalosporins.

The most common bacteria detected were Pseudomonas aeruginosa and Klebsiella pneumonia. The resistance situation for Staphylococcus aureus and Enterobacter cloacae was serious. It is necessary to pay great attention to the control of hospital-acquired infections caused by Pseudomonas aeruginosa and Klebsiella pneumonia, and carry out the targeted monitoring of the detection of special bacteria resistance.