Effect of initial periodontal therapy on patients with type 2 diabetes mellitus

doi:10.3877/cma.j.issn.1674-1366.2008.04.008

Abstract

Abstract:

Objective

To evaluate the effect of initial therapy on the control of clinical variables and blood glucose level on type 2 diabetic patients with chronic periodontitis.

Methods

Fifty-two type 2 diabetic patients with chronic periodontitis were randomized into two groups（group A and group B）. Treatment including scaling and root planning with systemic use of doxycycline were given to patients in Group A， while patients in Group B were only provided ith systemic use of doxycycline. Clinical variables and glycated hemoglobin were assessed before and after the treatment.

Results

16 weeks after therapy， group A had a statistically significant reduction on plaque index and bleeding on probing （P＜0.001）， with a significant difference in plaque index between the two groups （P＜0.001）. Some improvements were observed on other clinical variables and glycated hemoglobin （HbA1c） level in both groups althongh statistical significance was not detected （P＞0.05）.

Conclusion

This study suggests that initial therapy is of value in maintaining periodontal health and may be beneficial to the reduction of blood glucose level in type 2 diabetic patients with chronic periodontitis.

Key words: Type 2 diabetes, Chronic periodontitis, Periodontal initial therapy, Glycated hemoglobin A1c

Yun FU, Yang NING, Yu-zhu ZHOU, Xiao-peng SU. Effect of initial periodontal therapy on patients with type 2 diabetes mellitus[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2008, 02(04): 359-362.

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Figures/Tables 1

临床指标	组别	例数	治疗前		治疗后		t	Pt	u^*	Pu^*	u^^	Pu^^
临床指标	组别	例数	$\bar{x}$ ±s	s _$\bar{x}$	$\bar{x}$ ±s	s _$\bar{x}$	t	Pt	u^*	Pu^*	u^^	Pu^^
PLI	实验组	23	3.23±0.18	0.86	1.57±0.09	0.43	8.30	＜0.001	0.23	＞0.05	9.42	＜0.001
	对照组	23	3.16±0.12	0.58	3.04±0.13	0.62	0.67	＞0.05
BOP	实验组	23	71.50±5.26	25.25	42.47±2.59	14.43	4.45	＜0.001	0.11	＞0.05	3.39	＞0.05
	对照组	23	70.69±6.77	32.50	58.18±3.85	18.48	1.61	＞0.05
PPD	实验组	23	3.86±0.13	0.62	3.42±0.24	1.15	1.62	＞0.05	0.39	＞0.05	0.76	＞0.05
	对照组	23	3.77±0.20	0.96	3.61±0.07	0.34	0.76	＞0.05
CAL	实验组	23	4.30±0.18	0.86	4.11±0.12	0.58	0.86	＞0.05	0.17	＞0.05	1.14	＞0.05
	对照组	23	4.25±0.23	1.10	4.20±0.78	3.74	0.06	＞0.05
HbA1c	实验组	23	8.26±0.31	1.49	7.49±0.28	1.34	1.85	＞0.05	0.07	＞0.05	0.34	＞0.05
	对照组	23	8.22±0.45	2.16	7.64±0.36	1.73	1.01	＞0.05

临床指标	组别	例数	治疗前		治疗后		t	Pt	u^*	Pu^*	u^^	Pu^^
临床指标	组别	例数	$\bar{x}$ ±s	s _$\bar{x}$	$\bar{x}$ ±s	s _$\bar{x}$	t	Pt	u^*	Pu^*	u^^	Pu^^
PLI	实验组	23	3.23±0.18	0.86	1.57±0.09	0.43	8.30	＜0.001	0.23	＞0.05	9.42	＜0.001
	对照组	23	3.16±0.12	0.58	3.04±0.13	0.62	0.67	＞0.05
BOP	实验组	23	71.50±5.26	25.25	42.47±2.59	14.43	4.45	＜0.001	0.11	＞0.05	3.39	＞0.05
	对照组	23	70.69±6.77	32.50	58.18±3.85	18.48	1.61	＞0.05
PPD	实验组	23	3.86±0.13	0.62	3.42±0.24	1.15	1.62	＞0.05	0.39	＞0.05	0.76	＞0.05
	对照组	23	3.77±0.20	0.96	3.61±0.07	0.34	0.76	＞0.05
CAL	实验组	23	4.30±0.18	0.86	4.11±0.12	0.58	0.86	＞0.05	0.17	＞0.05	1.14	＞0.05
	对照组	23	4.25±0.23	1.10	4.20±0.78	3.74	0.06	＞0.05
HbA1c	实验组	23	8.26±0.31	1.49	7.49±0.28	1.34	1.85	＞0.05	0.07	＞0.05	0.34	＞0.05
	对照组	23	8.22±0.45	2.16	7.64±0.36	1.73	1.01	＞0.05

References 11

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