| ［1］ |
Morsczeck C. Mechanisms during osteogenic differentiation in human dental follicle cells［J］. Int J Mol Sci，2022，23（11）：5945.DOI：10.3390/ijms23115945.
|
| ［2］ |
Ott N，Faletti L，Heeg M，et al.JAKs and STATs from a clinical perspective：Loss - of - function mutations，gain - of - function mutations，and their multidimensional consequences［J］. J Clin Immunol，2023，43（6）：1326-1359. DOI：10.1007/s10875-023-01483-x.
|
| ［3］ |
Takeda K，Noguchi K，Shi W，et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality［J］. Proc Natl Acad Sci U S A，1997，94（8）：3801-3804. DOI：10.1073/pnas.94.8.3801.
|
| ［4］ |
Minegishi Y. The signal transducer and activator of transcription 3 at the center of the causative gene network of the hyper-IgE syndrome［J］. Curr Opin Immunol，2023，80：102264. DOI：10.1016/j.coi.2022.102264.
|
| ［5］ |
Esposito L，Poletti L，Maspero C，et al. Hyper-IgE syndrome：Dental implications［J］. Oral Surg Oral Med Oral Pathol Oral Radiol，2012，114（2）：147-153. DOI：10.1016/j.oooo.2012.04.005
|
| ［6］ |
Zou S，Tong Q，Liu B，et al. Targeting STAT3 in cancer immunotherapy［J］. Mol Cancer，2020，19（1）：145. DOI：10.1186/s12943-020-01258-7.
|
| ［7］ |
Tolomeo M，Cascio A. The multifaced role of STAT3 in cancer and its implication for anticancer therapy［J］. Int J Mol Sci，2021，22（2）：603.DOI：10.3390/ijms22020603.
|
| ［8］ |
Bravenboer N，Oostlander AE，van Bodegraven AA.Bone loss in patients with inflammatory bowel disease：Cause，detection and treatment［J］. Curr Opin Gastroenterol，2021，37（2）：128-134.DOI：10.1097/mog.0000000000000710.
|
| ［9］ |
Hashemi M，Sabouni E，Rahmanian P，et al. Deciphering STAT3 signaling potential in hepatocellular carcinoma：Tumorigenesis，treatment resistance，and pharmacological significance［J］. Cell Mol Biol Lett，2023，28（1）：33. DOI：10.1186/s11658-023-00438-9.
|
| ［10］ |
Liu Y，Liao S，Bennett S，et al. STAT3 and its targeting inhibitors in osteosarcoma［J］. Cell Prolif，2021，54（2）：e12974.DOI：10.1111/cpr.12974.
|
| ［11］ |
Tesoriere A，Dinarello A，Argenton F. The roles of post -translational modifications in STAT3 biological activities and functions［J］. Biomedicines，2021，9（8）：956. DOI：10.3390/biomedicines9080956.
|
| ［12］ |
Davis SD，Schaller J，Wedgwood RJ. Job's Syndrome. Recurrent，"cold"，staphylococcal abscesses［J］. Lancet，1966，1（7445）：1013-1015.DOI：10.1016/s0140-6736（66）90119-x.
|
| ［13］ |
Zhang B，Meng B，Viloria E，et al.The role of epithelial Stat3 in amelogenesis during mouse incisor renewal［J］. Cells Tissues Organs，2018，205（2）：63-71.DOI：10.1159/000486745.
|
| ［14］ |
da Cunha JM，da Costa-Neves A，Kerkis I，et al. Pluripotent stem cell transcription factors during human odontogenesis［J］.Cell Tissue Res，2013，353（3）：435-441.DOI：10.1007/s00441-013-1658-y.
|
| ［15］ |
Goel S，Sahu S，Minz RW，et al. STAT3-mediated transcriptional regulation of osteopontin in STAT3 loss-of-function related hyper IgE syndrome［J］. Front Immunol，2018，9：1080. DOI：10.3389/fimmu.2018.01080.
|
| ［16］ |
Chan L，Lu J，Feng X，et al. Loss of Stat3 in Osterix+ cells impairs dental hard tissues development［J］. Cell Biosci，2023，13（1）：75.DOI：10.1186/s13578-023-01027-1.
|
| ［17］ |
Pandya M，Diekwisch TGH. Amelogenesis：Transformation of a protein-mineral matrix into tooth enamel［J］.J Struct Biol，2021，213（4）：107809.DOI：10.1016/j.jsb.2021.107809.
|
| ［18］ |
Nudelman F，Kröger R. Enhancing strength in mineralized collagen［J］.Science，2022，376（6589）：137-138.DOI：10.1126/science.abo1264.
|
| ［19］ |
Lebeis IB，de Souza DV，Mennitti LV，et al. Proinflammatory state in the odontogenesis of fetuses exposed to different types of fatty acids during pregnancy［J］. Med Princ Pract，2022，31（6）：540-547.DOI：10.1159/000526777.
|
| ［20］ |
Fan L，Ou YJ，Zhu YX，et al. Lif deficiency leads to iron transportation dysfunction in ameloblasts［J］. J Dent Res，2022，101（1）：63-72.DOI：10.1177/00220345211011986.
|
| ［21］ |
Sarper SE，Inubushi T，Kurosaka H，et al. Runx1 - Stat3 signaling regulates the epithelial stem cells in continuously growing incisors［J］.Sci Rep，2018，8（1）：10906.DOI：10.1038/s41598-018-29317-6.
|
| ［22］ |
Huang L，Chen X，Yang X，et al. Elucidating epigenetic mechanisms governing odontogenic differentiation in dental pulp stem cells：An in-depth exploration［J］. Front Cell Dev Biol，2024，12：1394582.DOI：10.3389/fcell.2024.1394582.
|
| ［23］ |
Xu K，Xiao J，Zheng K，et al. MiR-21/STAT3 signal is involved in odontoblast differentiation of human dental pulp stem cells mediated by TNF-α［J］.Cell Reprogram，2018，20（2）：107-116.DOI：10.1089/cell.2017.0042.
|
| ［24］ |
Liao C，Ou Y，Wu Y，et al. Sclerostin inhibits odontogenic differentiation of human pulp-derived odontoblast-like cells under mechanical stress［J］. J Cell Physiol，2019，234（11）：20779-20789.DOI：10.1002/jcp.28684.
|
| ［25］ |
Zhou Y，Qian M，Liang Y，et al. Effects of leukemia inhibitory factor on proliferation and odontoblastic differentiation of human dental pulp cells［J］. J Endod，2011，37（6）：819-824. DOI：10.1016/j.joen.2011.02.031.
|
| ［26］ |
Peng Z，Liu L，Zhang W，et al.Pluripotency of dental pulp cells and periodontal ligament cells was enhanced through cell-cell communication via STAT3/Oct-4/Sox2 signaling［J］. Stem Cells Int，2021，2021：8898506.DOI：10.1155/2021/8898506.
|
| ［27］ |
Oh M，Zhang Z，Mantesso A，et al. Endothelial - initiated crosstalk regulates dental pulp stem cell self-renewal［J］. J Dent Res，2020，99（9）：1102-1111. DOI：10.1177/002203452092 5417.
|
| ［28］ |
Huang YW，Lin CY，Chin YT，et al. 2，3，5，4'-tetrahydroxystilbene-2-O-b-D-glucoside triggers the pluripotent-like possibility of dental pulp stem cells by activating the JAK2/STAT3 axis：Preliminary observations［J］. J Dent Sci，2021，16（2）：599-607.DOI：10.1016/j.jds.2020.10.011.
|
| ［29］ |
Zhong J，Shibata Y，Wu C，et al. Functional non-uniformity of periodontal ligaments tunes mechanobiological stimuli across softand hard-tissue interfaces［J］. Acta Biomater，2023，170：240-249.DOI：10.1016/j.actbio.2023.08.047.
|
| ［30］ |
Wang L，Wang Y，Du M，et al. Inhibition of Stat3 signaling pathway decreases TNF-α-induced autophagy in cementoblasts［J］. Cell Tissue Res，2018，374（3）：567-575. DOI：10.1007/s00441-018-2890-2.
|
| ［31］ |
Yong J，Gröger S，von Bremen J，et al. Ciliary neurotrophic factor（CNTF）inhibits in vitro cementoblast mineralization and induces autophagy，in part by STAT3/ERK commitment［J］.Int J Mol Sci，2022，23（16）：9311.DOI：10.3390/ijms23169311.
|
| ［32］ |
Yong J，von Bremen J，Ruiz-Heiland G，et al. Adiponectin interacts in-vitro with cementoblasts influencing cell migration，proliferation and cementogenesis partly through the MAPK signaling pathway［J］.Front Pharmacol，2020，11：585346.DOI：10.3389/fphar.2020.585346.
|
| ［33］ |
Hu Y，Ren B，Cheng L，et al. Candida species in periodontitis：A new villain or a new target？［J］. J Dent，2024：105138. DOI：10.1016/j.jdent.2024.105138.
|
| ［34］ |
Ambili R，Janam P，Saneesh Babu PS，et al. Differential expression of transcription factors NF - κB and STAT3 in periodontal ligament fibroblasts and gingiva of healthy and diseased individuals［J］. Arch Oral Biol，2017，82：19-26. DOI：10.1016/j.archoralbio.2017.05.010.
|
| ［35］ |
Jeong HW，Chang DS，Kim JS，et al. Role of cathepsin D induced by porphyromonas gingivalis lipopolysaccharide in periodontitis［J］. Eur J Oral Sci，2023，131（2）：e12923. DOI：10.1111/eos.12923.
|
| ［36］ |
Chen X，Dou J，Fu Z，et al. Macrophage M1 polarization mediated via the IL - 6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis［J］. J Appl Oral Sci，2022，30：e20220316. DOI：10.1590/1678-7757-2022-0316.
|
| ［37］ |
Zhang X，Zhang X，Qiu C，et al. The imbalance of Th17/Treg via STAT3 activation modulates cognitive impairment in P.gingivalis LPS-induced periodontitis mice［J］. J Leukoc Biol，2021，110（3）：511-524.DOI：10.1002/JLB.3MA0521-742RRR.
|
| ［38］ |
Arce M，Rodriguez-Peña M，Espinoza-Arrue J，et al. Increased STAT3 activation in periodontitis drives inflammatory bone loss［J］. J Dent Res，2023，102（12）：1366-1375. DOI：10.1177/00220345231192381.
|
| ［39］ |
Lu M，Zhang Y，Yuan X，et al. Increased serum α-tocopherol acetate mediated by gut microbiota ameliorates alveolar bone loss through the STAT3 signalling pathway in diabetic periodontitis［J］. J Clin Periodontol，2023，50（11）：1539-1552. DOI：10.1111/jcpe.13862.
|
| ［40］ |
Wright GM，Gassman NR. Glucose increases STAT3 activation，promoting sustained XRCC1 expression and increasing DNA repair［J］. Int J Mol Sci，2022，23（8）：4314. DOI：10.3390/ijms23084314.
|