目的

评价生物陶瓷材料iRoot BP Plus 应用于成熟恒牙不可复性牙髓炎冠髓切断术（FP）的治疗效果。

方法

收集2020 年6月至2021年10 月期间于广西医科大学附属口腔医院综合一门诊就诊，被诊断为“不可复性牙髓炎”，且在局部麻醉下使用iRoot BP Plus为盖髓剂进行FP的病例进行回顾性研究。随访资料收集至术后2年，通过对患者基本情况、术前病因、临床及影像学检查结果、诊断、术中治疗细节和术后临床体征，以及术后6、12、24个月影像学检查结果等资料数据进行汇总，统计各变量的例数及占比，评价其临床和影像学疗效。

结果

共收集25例患者（28颗患牙），其中男8例（32%）、女17例（68%），平均年龄（35.5±15.5）岁。术后3 ～24个月临床检查显示，患者原有症状消失且均无新发临床症状；术前7例根尖周阴影患者及2例牙周膜异常增宽患者在术后随访至12个月时均实现根尖阴影消失和牙周膜间隙恢复正常，其余16例术前根尖周影像正常患者均无新发根尖周异常。末次随访时，26颗患牙牙髓断面处见钙化桥形成，2颗患牙牙髓断面处未见明显钙化组织。

结论

iRoot BP Plus作为盖髓剂应用于成熟恒牙不可复性牙髓炎FP可取得良好的治疗效果。

Objective

To evaluate the effectiveness of the bioceramic material - iRoot BP Plus on full pulpotomy in mature permanent teeth with irreversible pulpitis.

Methods

A retrospective study was conducted on the cases diagnosed with"irreversible pulpitis"underwent full pulpotomy with iRoot BP Plus as pulp capping agent under local anesthesia in the general dental clinic I department，Hospital of Stomatology，Guangxi Medical University，from June 2020 to October 2021. The follow-up data were collected up to two years after operation. The patients' basic conditions，etiology，clinical and X-ray signs，diagnosis before the operation，intraoperative treatment details，and postoperative clinical signs at 3，6，12 and 24 months，and the radiographic data at 6，12 and 24 months were summarized.The number and proportion of each variable were counted to evaluate its clinical and radiographic efficacy.

Results

A total of 25 patients and 28 teeth were collected，including 8 males（32%）and 17 females（68%）with the average age of（35.5 ± 15.5）years old. At the follow-up 3 to 24 months，the clinical examination showed that the original symptoms disappeared and there were no new clinical symptoms in all cases. The imaging examination at the follow-up 6 to 24 months showed that all 7 cases with periapical radiolucency and 2 cases with abnormal widening of periodontal ligament before operation turned to normal radiographic manifestations in follow-up 12 months. No new periapical radiolucency was found in 16 patients with normal periapical images before operation during the follow-up.In the last follow-up，26 teeth showed hard tissue bridge formation under the capping material，and no obvious hard tissue bridge formation was found in 2 teeth.

Conclusion

iRoot BP Plus as a kind of pulp capping material applied in full pulpotomy of mature permanent teeth with irreversible pulpitis could achieve good therapeutic effectiveness.