| [1] |
Love RM, Jenkinson HF. Invasion of dentinal tubules by oral bacteria[J]. Crit Rev Oral Biol Med，2002，13(2):171-183.
|
| [2] |
Couve E, Osorio R, Schmachtenberg O. The amazing odontoblast：activity，autophagy，and aging[J]. J Dent Res，2013，92(9):765-772.
|
| [3] |
Veerayutthwilai O, Byers MR, Pham TT，et al. Differential regulation of immune responses by odontoblasts[J]. Oral Microbiol Immunol，2007，22(1):5-13.
|
| [4] |
Goldberg M, Farges JC, Lacerda-Pinheiro S，et al. Inflammatory and immunological aspects of dental pulp repair[J]. Pharmacol Res，2008，58(2):137-147.
|
| [5] |
Goldberg M, Lasfargues JJ. Pulpo-dentinal complex revisited[J]. J Dent，1995，23(1):15-20.
|
| [6] |
Fransson H, Petersson K, Davies JR. Effects of bacterial products on the activity of odontoblast-like cells and their formation of type 1 collagen[J]. Int Endod J，2014，47(4):397-404.
|
| [7] |
Staquet MJ, Durand SH, Colomb E，et al. Different roles of odontoblasts and fibroblasts in immunity[J]. J Dent Res，2008，87(3):256-261.
|
| [8] |
Botero TM, Shelburne CE, Holland GR，et al. TLR4 mediates LPS-induced VEGF expression in odontoblasts[J]. J Endod，2006，32(10):951-955.
|
| [9] |
Mjör IA, Sveen OB, Heyeraas KJ. Pulp-dentin biology in restorative dentistry. Part 1：normal structure and physiology[J]. Quintessence Int，2001，32(6):427-446.
|
| [10] |
Boshtam M, Asgary S, Kouhpayeh S，et al. Aptamers Against Pro- and Anti-Inflammatory Cytokines：A Review[J]. Inflammation，2017，40(1):340-349.
|
| [11] |
Schröder NW, Morath S, Alexander C，et al. Lipoteichoic acid （LTA）of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor（TLR）-2，lipopolysaccharide-binding protein（LBP），and CD14，whereas TLR-4 and MD-2 are not involved[J]. J Biol Chem，2003，278(18):15587-15594.
|
| [12] |
Baek KT, Bowman L, Millership C，et al. The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone[J]. MBio，2016，7(4):e01228-16.
|
| [13] |
Durand SH, Flacher V, Roméas A，et al. Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts[J]. J Immunol，2006，176(5):2880-2887.
|
| [14] |
Dommisch H, Steglich M, Eberhard J，et al. Phosphatidylinositol-3-kinase inhibitor LY 294002 blocks Streptococcus mutans-induced interleukin（IL）-6 and IL-8 gene expression in odontoblast-like cells[J]. Int Endod J，2008，41(9):763-771.
|
| [15] |
Carrouel F, Staquet M, Keller J，et al. Lipopolysaccharide-binding protein inhibits toll-like receptor 2 activation by lipoteichoic acid in human odontoblast-like cells[J]. J Endod，2013，39(8):1008-1014.
|
| [16] |
Anggård E. Nitric oxide：mediator，murderer，and medicine[J]. Lancet，1994，343(8907):1199-1206.
|
| [17] |
Lind M, Hayes A, Caprnda M，et al. Inducible nitric oxide synthase：Good or bad？[J]. Biomed Pharmacother，2017(93):370-375.
|
| [18] |
Farges JC, Bellanger A, Ducret M，et al. Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation[J]. Front Physiol，2015(6):185.
|
| [19] |
Couble ML, Farges JC, Bleicher F，et al. Odontoblast differentiation of human dental pulp cells in explant cultures[J]. Calcif Tissue Int，2000，66(2):129-138.
|
| [20] |
Horst OV, Horst JA, Samudrala R，et al. Caries induced cytokine network in the odontoblast layer of human teeth[J]. BMC Immunol，2011(12):9.
|
| [21] |
Takeuchi O, Akira S. Pattern recognition receptors and inflammation[J]. Cell，2010，140(6):805-820.
|
| [22] |
Farges JC, Alliot-Licht B, Baudouin C，et al. Odontoblast control of dental pulp inflammation triggered by cariogenic bacteria[J]. Front Physiol，2013(4):326.
|
| [23] |
Medvedev AE. Toll-like receptor polymorphisms，inflammatory and infectious diseases，allergies，and cancer[J]. J Interferon Cytokine Res，2013，33(9):467-484.
|
| [24] |
Farges JC, Keller JF, Carrouel F，et al. Odontoblasts in the dental pulp immune response[J]. J Exp Zoo B Mol Dev Evol，2009，312B(5):425-436.
|
| [25] |
Jiang HW, Zhang W, Ren BP，et al. Expression of toll like receptor 4 in normal human odontoblasts and dental pulp tissue[J]. J Endod，2006，32(8):747-751.
|
| [26] |
Farges JC, Carrouel F, Keller JF，et al. Cytokine production by human odontoblast-like cells upon Toll-like receptor-2 engagement[J]. Immunobiology，2011，216(4):513-517.
|
| [27] |
Horst OV, Tompkins KA, Coats SR，et al. TGF-beta1 Inhibits TLR-mediated odontoblast responses to oral bacteria[J]. J Dent Res，2009，88(4):333-338.
|
| [28] |
席琼，胡巢凤. NOD样受体在炎症反应中的调控作用[J].生命科学，2010，22(5):454-458.
|
| [29] |
Lee YY, Chan CH, Hung SL，et al. Up-regulation of nucleotide-binding oligomerization domain 1 in inflamed human dental pulp[J]. J Endod，2011，37(10):1370-1375.
|
| [30] |
Lin ZM, Song Z, Qin W，et al. Expression of nucleotide-binding oligomerization domain 2 in normal human dental pulp cells and dental pulp tissues[J]. J Endod，2009，35(6):838-842.
|
| [31] |
Hosokawa Y, Hirao K, Yumoto H，et al. Functional Roles of NOD1 in Odontoblasts on Dental Pulp Innate Immunity[J]. Biomed Res Int，2016(2016):9325436.
|
| [32] |
Ting JP, Lovering RC, Alnemri ES，et al. The NLR gene family：a standard nomenclature[J]. Immunity，2008，28(3):285-287.
|
| [33] |
Song Z, Lin Z, He F，et al. NLRP3 is expressed in human dental pulp cells and tissues[J]. J Endod，2012，38(12):1592-1597.
|
| [34] |
Fukata M, Vamadevan AS, Abreu MT. Toll-like receptors （TLRs）and Nod-like receptors（NLRs）in inflammatory disorders[J]. Semin Immunol，2009，21(4):242-253.
|
| [35] |
王乐怡，吴欣怡. Toll样受体与NOD样受体在炎症中作用的研究进展[J].现代免疫学，2010，30(5):436-439.
|
| [36] |
Keller JF, Carrouel F, Staquet MJ，et al. Expression of NOD2 is increased in inflamed human dental pulps and lipoteichoic acid-stimulated odontoblast-like cells[J]. Innate Immun，2011，17(1):29-34.
|
| [37] |
Hirao K, Yumoto H, Takahashi K，et al. Roles of TLR2，TLR4，NOD2，and NOD1 in Pulp Fibroblasts[J]. J Dent Res，2009，88(8):762-767.
|
| [38] |
Mizushima N, Levine B. Autophagy in mammalian development and differentiation[J]. Nat Cell Biol，2010，12(9):823-830.
|
| [39] |
Deretic V, Saitoh T, Akira S. Autophagy in infection，inflammation and immunity[J]. Nat Rev Immunol，2013，13(10):722-737.
|
| [40] |
Virgin HW, Levine B. Autophagy genes in immunity[J]. Nat Immunol，2009，10(5):461-470.
|
| [41] |
肖孟景，李利根.自噬调控过度炎症研究进展[J].生理学报，2014，66(6):739-745.
|
| [42] |
Pei F, Lin H, Liu H，et al. Dual role of autophagy in lipopolysaccharide-induced preodontoblastic cells[J]. J Dent Res，2015，94(1):175-182.
|
| [43] |
Wang HS, Pei F, Chen Z，et al. Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss[J]. J Dent Res，2016，95(6):697-703.
|
| [44] |
Zero DT, Zandona AF, Vail MM，et al. Dental caries and pulpal disease[J]. Dent Clin North Am，2011，55(1):29-46.
|
| [45] |
Ozeki N, Yamaguchi H, Kawai R，et al. Cytokines induce MMP-3-regulated proliferation of embryonic stem cell-derived odontoblast-like cells[J]. Oral Dis，2014，20(5):505-513.
|
| [46] |
Tziafas D, Papadimitriou S. Role of exogenous TGF-beta in induction of reparative dentinogenesis in vivo[J]. Eur J Oral Sci，1998(106 Suppl 1):192-196.
|
| [47] |
Hu CC, Zhang C, Qian Q，et al. Reparative dentin formation in rat molars after direct pulp capping with growth factors[J]. J Endod，1998，24(11):744-751.
|
| [48] |
Zhang W, Walboomers XF, Jansen JA. The formation of tertiary dentin after pulp capping with a calcium phosphate cement，loaded with PLGA microparticles containing TGF-beta1[J]. J Biomed Mater Res A，2008，85(2):439-444.
|
| [49] |
Nakayama K, Hirata-Tsuchiya S, Okamoto K，et al. The Novel NF-kappaB Inhibitor，MTI-II Peptide Anti-Inflammatory Drug，Suppresses Inflammatory Responses in Odontoblast-Like Cells[J]. J Cell Biochem，2016，117(11):2552-2558.
|