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中华口腔医学研究杂志(电子版) ›› 2020, Vol. 14 ›› Issue (06) : 367 -372. doi: 10.3877/cma.j.issn.1674-1366.2020.06.005

所属专题: 文献

临床研究

牙周炎伴高血压患者在龈上洁治术中血压升高的相关因素分析
孟洋1, 王香兰1, 张晓敏1, 王万春1, 滕琦1,(), 孟焕新2   
  1. 1. 青岛市口腔医院牙周科 266001
    2. 北京大学口腔医学院·口腔医院牙周科 100081
  • 收稿日期:2020-05-08 出版日期:2020-12-01
  • 通信作者: 滕琦

Analysis of factors related to elevated blood pressure in patients with periodontitis accompanied by hypertension

Yang Meng1, Xianglan Wang1, Xiaomin Zhang1, Wanchun Wang1, Qi Teng1,(), Huanxin Meng2   

  1. 1. Department of Periodontology, Qingdao Stomatological Hospital, Qingdao 266001, China
    2. Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China
  • Received:2020-05-08 Published:2020-12-01
  • Corresponding author: Qi Teng
  • About author:
    Corresponding author: Teng Qi, Email:
  • Supported by:
    Supported by Projects of Medical and Health Technology Development Program in Shandong Province(2019WS150); Qingdao Key Health Discipline Development Fund(2020-2022); Medical and Scientific Research Guidance Plan of Qingdao(2019-WJZD135); Science and Technology Planning Project of Shinan District, Qingdao City(2020-2-012-YY)
引用本文:

孟洋, 王香兰, 张晓敏, 王万春, 滕琦, 孟焕新. 牙周炎伴高血压患者在龈上洁治术中血压升高的相关因素分析[J]. 中华口腔医学研究杂志(电子版), 2020, 14(06): 367-372.

Yang Meng, Xianglan Wang, Xiaomin Zhang, Wanchun Wang, Qi Teng, Huanxin Meng. Analysis of factors related to elevated blood pressure in patients with periodontitis accompanied by hypertension[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2020, 14(06): 367-372.

目的

研究牙周炎伴高血压患者在龈上洁治术中血压升高的相关因素,并进一步分析具体原因。

方法

收集2019年1—11月就诊于青岛市口腔医院牙周科门诊,且患有慢性牙周炎伴原发性高血压的初诊患者,均通过清晨自行口服降压药血压控制在收缩压(SBP)159 mmHg或舒张压(DBP)99 mmHg以下患者212例。分析比较患者在超声龈上洁治术前和术中血压的变化,并根据术中较术前血压升高(DBP波动≥4 mmHg)进行分组:血压升高组和血压升高不明显组。分析两组之间血压变化与临床相关因素[性别、年龄、心率(HR)、精神紧张、就诊时间(上/下午)]的关系,并进行多因素Logistic回归分析。

结果

牙周炎伴高血压患者超声龈上洁治术中的收缩压和舒张压,心率均显著高于术前[SBP术中 = (133.1 ± 15.0) mmHg、SBP术前 = (129.7 ± 13.4) mmHg,DBP术中 = (87.7 ± 10.9) mmHg、DBP术前 = (83.6 ± 9.6) mmHg,HR术中 = (77.4 ± 11.3)次/分钟、HR术前 = (74.2 ± 9.9)次/分钟],差异均有统计学意义(P<0.05)。通过对血压升高组和血压升高不明显组之间临床资料的比较显示:年龄(t = 2.49,P = 0.013)、精神紧张(χ2 = 16.27,P<0.001)、就诊时间(上/下午,χ2 = 5.87,P<0.001)差异均有统计学意义,而性别差异无统计学意义(t = 1.78,P = 0.181)。多因素Logistic回归分析结果显示,牙周炎伴高血压患者在超声洁治术过程中,年龄(OR = 1.033,95% CI = 1.001 ~ 1.065)、心率加快(OR = 4.073,95% CI = 2.165 ~ 7.661)、精神紧张(OR = 4.260,95% CI = 2.226 ~ 8.152)、下午就诊(OR = 2.376,95% CI = 1.242 ~ 4.545)均是术中血压升高的相关因素(P<0.05)。

结论

牙周炎伴高血压患者超声龈上洁治术中血压升高与年龄、心率、精神紧张、就诊时间(上/下午)密切相关,值得临床重点关注。

Objective

To study the related factors of elevated blood pressure in patients with periodontitis and hypertension during supragingival surgery and further analyze the specific reasons.

Methods

Newly diagnosed patients with chronic periodontitis and essential hypertension who visited the periodontal clinic of Qingdao Stomatological Hospital from January to November 2019 were collected and their blood pressure at systolic blood pressure (SBP) were under controlled through oral antihypertensive drugs in the morning. 212 patients with 159 mmHg or diastolic blood pressure (DBP) below 99 mmHg were enrolled. The changes of blood pressure before and during the operation of ultrasound supragingival cleansing were analyzed and compared. The patients were classified into two groups: one group with blood pressure increase and the other group without significant increased according to the increase in blood pressure (DBP fluctuation ≥4 mmHg) during the operation compared with the preoperative blood pressure. The relationship between blood pressure changes and clinical factors such as gender, age, heart rate (HR) , emotional stress, morning/afternoon (AM/PM) between the two groups were analyzed and multivariate logistic regression analysis was applied.

Results

In patients with periodontitis and hypertension, the systolic and diastolic blood pressures during the ultrasound supragingival surgery, and the heart rate were significantly higher than those before the surgery [SBPIntraoperative = (133.1 ± 15.0) mmHg, SBPPreoperative = (129.7 ± 13.4) mmHg, DBPIntraoperative = (87.7 ± 10.9) mmHg, DBPPreoperative = (83.6 ± 9.6) mmHg, HR Intraoperative = (77.4 ± 11.3) beats/min, HRPreoperative = (74.2 ± 9.9) beats/min], and the differences were statistically significant (P<0.05) . The comparison of clinical factors between the two groups showed statistically significant difference at age (t = 2.49, P = 0.013) , emotional stress (χ2 = 16.27, P<0.001) , visit time (AM/PM) (χ2 = 5.87, P<0.001) , while the gender factor without statistically significant difference (t = 1.78, P = 0.181) . The results of multivariate logistic regression analysis showed that the age (OR = 1.033, 95% CI = 1.001-1.065) and increased heart rate (OR = 4.073, 95% CI = 2.165) of patients with periodontitis and hypertension during the ultrasonic cleansing procedure (OR = 4.073, 95% CI = 2.165-7.661) , emotional/mental stress (OR = 4.260, 95% CI = 2.226-8.152) , and afternoon visits (PM) (OR = 2.376, 95% CI = 1.242-4.545) are all related factors for increased blood pressure during surgery (P<0.05) .

Conclusion

The elevation of blood pressure in patients with periodontitis and hypertension during the supragingival scaling are closely related to age, heart rate, emotional tension and treatment time (AM/PM) , which is worthy of clinical attention.

表1 212例高血压伴牙周病患者在超声龈上洁治术前和术中血压、心率的比较(±s
表2 高血压伴牙周病患者在超声龈上洁治术前及术中血压升高组与升高不明显组临床资料比较
表3 高血压伴牙周病患者在超声龈上洁治术前及术中血压升高的二元Logistic回归影响因素分析
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