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中华口腔医学研究杂志(电子版) ›› 2023, Vol. 17 ›› Issue (05) : 376 -380. doi: 10.3877/cma.j.issn.1674-1366.2023.05.010

综述

白藜芦醇治疗牙周炎和糖尿病的新进展
叶弘, 吕婧喆, 钟良军()   
  1. 杭州师范大学附属医院,杭州师范大学,杭州 310000
  • 收稿日期:2023-06-07 出版日期:2023-10-01
  • 通信作者: 钟良军

New study progress of resveratrol in the treatment of periodontitis and diabetes

Hong Ye, Jingzhe Lyu, Liangjun Zhong()   

  1. Hangzhou Normal University Affiliated Hospital, Hangzhou Normal University, Hangzhou 310000, China
  • Received:2023-06-07 Published:2023-10-01
  • Corresponding author: Liangjun Zhong
  • Supported by:
    National Natural Science Foundation of China(81570989); Hangzhou Health Science and Technology Plan Project(Z20200046); Hangzhou Normal University Graduate Research Innovation Promotion Project(2022HSDYJSKY078)
引用本文:

叶弘, 吕婧喆, 钟良军. 白藜芦醇治疗牙周炎和糖尿病的新进展[J]. 中华口腔医学研究杂志(电子版), 2023, 17(05): 376-380.

Hong Ye, Jingzhe Lyu, Liangjun Zhong. New study progress of resveratrol in the treatment of periodontitis and diabetes[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(05): 376-380.

牙周炎和糖尿病是临床上常见的疾病,对患者的健康及生活产生巨大影响。近年来学者研究证实这两种疾病具有很强相关性,因此治疗牙周炎和糖尿病的药物也成为研究热点。白藜芦醇是一种来自于天然植物的多酚类化合物,具有抗炎、抗氧化、降低血脂和调节代谢等作用,同时白藜芦醇不良反应少,获取途径广泛,价格低廉,是一种在牙周炎和糖尿病治疗中应用潜力巨大的辅助药物,也是解决关于慢性炎症性疾病中细菌耐药性问题的一个新思路。本文综述了近年来白藜芦醇应用于牙周炎及糖尿病治疗中的新进展,为进一步研究与应用提供新的思路。

Periodontitis and diabetes are common diseases in clinic, which have a huge impact on the health and life of patients. In recent years, it was proven that these two diseases have a strong correlation, so drugs for treating periodontitis and diabetes have also become a research hotspot. Resveratrol is a kind of polyphenol compound from natural plants, which has anti-inflammatory, antioxidant, lipid lowering and metabolic regulating effects. At the same time, it also has the advantages of small toxic side effects, wide access, low price, etc. It is a kind of auxiliary antibacterial drug with great potential in the treatment of periodontitis and diabetes, and also a new way to solve the problem of bacterial resistance in chronic inflammatory diseases. This article reviewed the new progress of resveratrol in the treatment of periodontitis and diabetes in recent years, in order to provide new ideas for its further research and application.

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