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中华口腔医学研究杂志(电子版) ›› 2016, Vol. 10 ›› Issue (02) : 148 -150. doi: 10.3877/cma.j.issn.1674-1366.2016.02.013

所属专题: 口腔医学 文献

综述

Wnt/β-catenin信号通路影响牙本质形成及再生的研究进展
车彦霖1, 吴家媛2,()   
  1. 1. 563099 遵义医学院口腔学院
    2. 563099 遵义医学院口腔学院;563099 贵州省高等学校口腔疾病研究特色重点实验室,遵义市口腔疾病研究重点实验室
  • 收稿日期:2015-10-12 出版日期:2016-04-01
  • 通信作者: 吴家媛
  • 基金资助:
    国家自然科学基金(81460102); 贵州省科技创新人才团队资助项目(黔科合人才团队[2013]4026); 贵州省高等学校特色重点实验室建设项目(黔教合KY字[2013]109); 贵州省科学技术基金(黔科合J字LKZ[2013]11号); 遵义医学院博士启动基金(ZMKD2012-022)

The effect of Wnt/β-catenin signaling pathway on dentinogenesis and dentin regeneration

Yanlin Che1, Jiayuan Wu2,()   

  1. 1. School of Stomatology, Zunyi Medical University, Zunyi 563099, China
    2. School of Stomatology, Zunyi Medical University, Zunyi 563099, China; Special Key Laboratory of Oral Diseases Research, Institutions of Higher Learning In Guizhou Province, Key Laboratory of Oral Diseases Research, In Zunyi City, Zunyi 563099, China
  • Received:2015-10-12 Published:2016-04-01
  • Corresponding author: Jiayuan Wu
  • About author:
    Corresponding author: Wu Jiayuan, Email:
引用本文:

车彦霖, 吴家媛. Wnt/β-catenin信号通路影响牙本质形成及再生的研究进展[J]. 中华口腔医学研究杂志(电子版), 2016, 10(02): 148-150.

Yanlin Che, Jiayuan Wu. The effect of Wnt/β-catenin signaling pathway on dentinogenesis and dentin regeneration[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2016, 10(02): 148-150.

Wnt/β-catenin信号通路是Wnt通路中的经典途径,在牙的发生中发挥着重要作用。研究表明,Wnt/β-catenin信号通路在牙本质的形成过程中扮演着重要角色,本文就近年来相关研究对Wnt/β-catenin信号通路在成牙本质细胞分化和牙本质发生及再生中的作用及影响作一阐述。

Wnt/β-catenin signaling pathway is a canonical way which has an important influence on the tooth development. Many recent studies showed that it also plays an essential role during the dentin formation. This review aims to explain the effect of Wnt/β-catenin signaling pathway on odontoblast differentiation, dentinogenesis and dentin regeneration.

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