分析新疆喀什地区儿童颈部淋巴结结核（CTL）的临床特点及治疗效果，以提高儿童CTL的诊治能力。

收集喀什地区第一人民医院2014年4月至2019年4月期间住院的CTL患儿病例资料，共131例，分析一般情况、临床表现、淋巴结受累情况等。从淋巴结肿胀消退情况、全身中毒症状的改善、颈部外观满意度评价、手术并发症、药物不良反应等方面描述治疗效果。应用SPSS 17.0软件包进行统计分析，计数资料以百分比表示。

男女比例为1∶1.2，0 ~ 3岁发病52例（39.69%）。CTL发生部位单侧颈部93例（70.99%）、右侧颈部51例（38.93%）。不伴有肺结核83例（63.36%）。全身中毒症状纳差（36/147，24.49%）、低热（12/147，8.16%）、盗汗（22/147，14.96%）、乏力（19/147，12.93%）。有结核病接触史69例（52.67%）。颈部淋巴结分区：Ⅰ区（11/204，5.39%）、Ⅱ区（37/204，18.14%）、Ⅲ区（63/204，30.88%）、Ⅳ区（41/204，20.10%）、Ⅴ区（52/204，25.49%）。CTL仅累及1个或2个淋巴结区域85例（50.90%），3个或以上淋巴结区域46例（27.54%）。回访87例接受治疗的患者，行单纯全身抗结核药物治疗36例、手术联合全身抗结核治疗的51例。手术联合抗结核药物治疗在颈部肿大淋巴结消退、颈部外观满意度、全身中毒症状缓解等方面均优于单纯抗结核药物治疗，未出现严重的手术并发症。

喀什地区儿童CTL女性多见，0 ~ 3岁发病率较高，右颈部累及较多，多数不伴有肺结核，全身中毒症状发生率低，Ⅲ、Ⅴ区累及较多。手术联合全身抗结核治疗治疗效果良好，手术并发症及药物不良反应可控制。

To investigate the clinical feature and therapeutic effect of cervical lymph node tuberculosis (CTL) in children in Kashgar area of Xinjiang.

The following clinical information and data were collected from 131 cases of children CTL, who admitted in first people′s hospital of kashgar during April 2014 to April 2019. The general situation, clinical manifestations, location of lymph node tuberculosis, treatment and treatment outcomes were analyzed. The regression of lymph node swelling, improvement of tuberculosis symptoms, evaluation of neck aesthetics, surgical complications and adverse drug reactions were described. Counting data were expressed by percentages.

The ratio of men to women was 1∶1.2, with 52 cases ranging in 0 ~ 3 years old (39.69%) . There was 93 cases of CTL located in unilateral side of the neck, and 51 cases in the right side (38.93%) . The complicated pulmonary tuberculosis was not shown in 83 cases (63.36%) of the patients. The associated manifestations included loss of appetite (36/147, 24.49%) , fever (12/147, 8.16%) , nightsweats (22/147, 14.96%) , and fatigue (19/147, 12.93%) . 69 cases had tuberculosis contact history (69/131, 52.67%) . The Levels of CTL distributed in Level Ⅰ (11/204, 5.39%) , Level Ⅱ (37/204, 18.14%) , Level Ⅲ (63/204, 30.88%) , Level Ⅳ (41/204, 20.10%) , and Level Ⅴ (52/204, 25.49%) . 85 CTL cases involved in one or two Levels (50.90%) , and 46 cases in three or more than three levels (27.54%) . 36 cases were treated with anti-tuberculosis drugs, and 51 cases with surgery and anti-tuberculosis drugs treatment. The regression of enlarged lymph nodes, satisfaction of neck appearance, and the remission of symptoms of tuberculosis poisoning in surgery and anti-tuberculosis drugs treatment group were significantly better than anti-tuberculosis drugs group. There were no serious surgical complications.

Children CTL in Kashgar area of Xinjiang shows the following features: female patients more than male patients; 0-3 years old incidence higher, the right neck involvement more often, most cases without pulmonary tuberculosis, tuberculosis symptom incidence lower, and more involvement in Level Ⅲ and Ⅴ. The combination of surgery and anti-tuberculosis treatment has a good therapeutic effect, and the surgical complications and adverse drug reactions can be controled.