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中华口腔医学研究杂志(电子版) ›› 2017, Vol. 11 ›› Issue (03) : 164 -168. doi: 10.3877/cma.j.issn.1674-1366.2017.03.006

所属专题: 文献

基础研究

不同烧结温度对猪骨羟基磷灰石理化性能的影响
李龙飞1, 李志鹏1, 刘润恒1, 陈卓凡1,()   
  1. 1. 510055 广州,中山大学光华口腔医学院·附属口腔医院,广东省口腔医学重点实验室
  • 收稿日期:2017-02-17 出版日期:2017-06-01
  • 通信作者: 陈卓凡
  • 基金资助:
    国家自然科学基金(81470783、81600914); 广东省自然科学基金(2015A030311051、2016A030310173)

Effects of different sintering temperature on the physicochemical properties of porcine hydroxyapatite

Longfei Li1, Zhipeng Li1, Runheng Liu1, Zhuofan Chen1,()   

  1. 1. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2017-02-17 Published:2017-06-01
  • Corresponding author: Zhuofan Chen
  • About author:
    Corresponding author: Chen Zhuofan, Email:
引用本文:

李龙飞, 李志鹏, 刘润恒, 陈卓凡. 不同烧结温度对猪骨羟基磷灰石理化性能的影响[J/OL]. 中华口腔医学研究杂志(电子版), 2017, 11(03): 164-168.

Longfei Li, Zhipeng Li, Runheng Liu, Zhuofan Chen. Effects of different sintering temperature on the physicochemical properties of porcine hydroxyapatite[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2017, 11(03): 164-168.

目的

探讨不同烧结温度对猪骨羟基磷灰石(HA)理化性能的影响。

方法

分别用600、800、1000 ℃不同温度烧结预处理的猪骨,通过扫描电镜(SEM)、X射线能谱(EDX)、X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)等方法分析不同温度烧结对制备的HA表面形貌、元素组成、晶相结构以及官能基团等理化参数的影响。

结果

猪骨经化学预处理与高温烧结,可制备获得较纯相生物羟基磷灰石,600、800、1000 ℃烧结制备的骨块样品钙磷比分别为1.49、1.55、1.58。随着烧结温度的升高,材料的结晶度变高,晶粒变大且有聚集趋势,所含碳酸根减少。

结论

烧结温度由600 ℃升至1000 ℃,猪骨HA理化性能发生改变,较低温烧结制备的猪骨HA具备更佳的理化性能。

Objective

To study the effect of different sintering temperature on the physiochemical properties of porcine hydroxyapatite (HA) .

Methods

The pretreated porcine bone blocks were sintered at 600, 800 and 1000 ℃ to prepare biological hydroxyapatite. The morphology, chemical composition, crystal characteristics and functional groups of the heated samples were determined through scanning electron microscopy (SEM) , energy dispersive X-ray spectroscopy (EDX) , X-ray diffraction (XRD) , fourier transform infrared spectroscopy (FTIR) .

Results

Pure phase biological hydroxyapatite could be prepared from pretreated porcine bone through thermal treatment. The calcium/phosphorus ratios of the bone samples prepared by sintering at 600, 800 and 1000 ℃ were 1.49, 1.55 and 1.58, respectively. With the increase of sintering temperature, the grain size of hydroxyapatite became larger and the aggregation tendency was increased. However, the content of carbonate group was decreased.

Conclusions

With the increase of sintering temperature from 600 ℃ to 1000 ℃, the physiochemical properties of porcine hydroxyapatite was changed, while lower temperature sintering preparation of porcine hydroxyapatite with better physiochemical properties.

表1 不同温度下烧结骨块样品的元素原子百分比(mol%)
图1 烧结的骨块样品的SEM形貌
图2 不同温度烧结骨块样品的X射线衍射分析图谱
图3 不同温度烧结骨块样品的傅里叶红外吸收光谱
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