研究预防性使用脱敏剂对牙漂白术后牙齿敏感的影响。

选取2015年5月至2016年10月于佛山市口腔医院就诊的20例将进行诊室漂白且符合纳入标准的患者，20例患者按纳入顺序编号，随机抽取10例左侧前牙为实验组、右侧前牙为对照组，另外10例则左侧前牙为对照组、右侧前牙为实验组。实验组在漂白治疗前对即将进行漂白的牙使用脱敏剂（极固宁），对照组则使用安慰剂（蒸馏水）。采用视觉模拟疼痛量表（VAS）比较患者左右侧前牙（实验组与对照组）漂白术后即刻及漂白术后1周内的牙齿敏感发生率和牙齿敏感程度，并分别采用卡方检验和Mann-Whitney秩和检验进行统计学分析。

牙漂白术后即刻，实验组有28.33%、对照组有62.50%的牙齿出现牙齿敏感症状；牙漂白术后1周内，实验组有11.67%、对照组有43.33%的牙齿出现牙齿敏感症状。术后即刻和术后1周内，对照组牙齿敏感发生率高于实验组，差异有统计学意义（χ²_即刻= 29.606、χ²_术后= 30.178，P<0.001）。术后即刻和术后1周内对照组发生牙齿敏感程度均高于实验组，差异有统计学意义（Z_即刻=-5.999、Z_术后=-5.659，P<0.001）。

预防性使用脱敏剂可以降低牙漂白术后牙齿敏感的发生率，并能有效减轻患者的牙齿敏感症状。

To study the effects of the preventive application of a desensitizing agent before tooth bleaching on tooth sensitivity.

Twenty patients, who received in-office bleaching in Affiliated Stomatological Hospital of Foshan University from May 2015 to Oct 2016, were recruited according to the inclusion criteria. The patients were numbered in sequence and randomly divided into two groups. For group one, their left anterior teeth were set as the experimental group and the right side as the control. In contrast, in group two, the left anterior teeth were taken as the control group and the right side as the experimental group. Desensitizing agent (Green Or) for the experimental group and placebo (distilled water) for the control group were applied on tooth surface before the bleaching treatment. The incidence and intensity of tooth sensitivity immediate after operation and within 1 week were recorded using VAS scale. The Chi-square test and Mann-Whitney rank-sum test were applied for statistical analysis.

The incidence of tooth sensitivity immediate after operation was 28.33% and 62.50% in the experimental and control group, respectively. Meanwhile, the sensitivity in 1 week after tooth bleaching was 11.67% and 43.33% in the experimental and control group, respectively. The incidence of tooth sensitivity immediate after operation and within 1 week was significantly higher in the control group than that in the experimental group (χ²_imm=29.606, χ^2post=30.178, P<0.001) . The intensity of tooth sensitivity immediate after operation and within 1 week was significantly higher in the control group than that in the experimental group (Z_imm=-5.999, Z_post=-5.659, P<0.001) .

The preventive application of the desensitizing agent before tooth bleaching can effectively reduce the incidence of tooth sensitivity and relief the symptom.