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中华口腔医学研究杂志(电子版) ›› 2015, Vol. 09 ›› Issue (05) : 425 -428. doi: 10.3877/cma.j.issn.1674-1366.2015.05.015

所属专题: 口腔医学 文献

综述

乳酸链球菌素的特性及抗菌材料在口腔中应用的研究进展
苏美旋1, 麦穗1,()   
  1. 1. 510055 广州,中山大学光华口腔医学院·附属口腔医院,广东省口腔医学重点实验室
  • 收稿日期:2015-05-17 出版日期:2015-10-01
  • 通信作者: 麦穗
  • 基金资助:
    广东省科技计划国际合作项目(2013B051000031); 广东省自然科学基金(2014A030313068)

The characteristics of nisin and the research progress of antibacterial material applied in the oral cavity

Meixuan Su1, Sui Mai1,()   

  1. 1. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2015-05-17 Published:2015-10-01
  • Corresponding author: Sui Mai
  • About author:
    Corresponding author: Mai Sui, Email:
引用本文:

苏美旋, 麦穗. 乳酸链球菌素的特性及抗菌材料在口腔中应用的研究进展[J]. 中华口腔医学研究杂志(电子版), 2015, 09(05): 425-428.

Meixuan Su, Sui Mai. The characteristics of nisin and the research progress of antibacterial material applied in the oral cavity[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2015, 09(05): 425-428.

致龋菌对树脂粘接材料的黏附及其在牙体组织表面产酸可引起继发龋,最终导致牙体缺损修复的失败。乳酸链球菌素(nisin)作为乳酸链球菌产生的一种3.4 kDa的抗菌肽,通过在细菌的细胞膜上产生孔道杀菌,对口腔致龋菌有明显抑制作用,具有应用于抗菌材料防止继发龋的潜能。本文就nisin的特性及其口腔抗菌材料中的应用研究进展作一综述。

The cariogenic bacteria adhesion to the resin bonding material and acid metabolites on the surface the dental tissue can cause secondary caries, andresult in the failure of restorations. Nisin is a 3.4 kDa antimicrobial peptide that kill the bacteria by pores on the surface of the cell membrane. It has significant inhibitory effect of cariogenic bacteria, and is considered to apply in antibacterial materials to prevent secondary caries. This review is to summarize the characteristics of nisin and its latest developments in dental field.

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