骨性Ⅲ类错畸形表现为下颌发育过度和（或）上颌骨发育不足，磨牙近中关系、前牙反、Ⅲ类骨面型显著、下颌前突伴或不伴功能性反，对口腔功能、颜面美观和心理健康有较严重的影响，矫治难度较大，常常需要配合外科手术治疗。通过报道了1例成人骨性Ⅲ类错畸形的患者通过非手术，非微种植体植入的正畸掩饰性治疗，分析原因，并讨论诊疗、鉴别诊断及预防措施，以期对临床医师的处理提供帮助。

Skeletal class Ⅲmalocclusion，manifested by excessive mandibular growth and/or hypoplasia of the maxilla，is typified by molar mesial occlusion，anterior crossbite，pronounced classⅢskeletal morphology，and mandibular prognathism，either with or without functional crossbite.This condition exerts a profound impact on oral functionality，facial esthetics，and psychological health，posing a significant therapeutic challenge that frequently necessitates orthognathic surgery.This case report presents an adult patient with skeletal class Ⅲmalocclusion who was treated with non-surgical，nonmicroimplant orthodontic camouflage therapy.The etiology is scrutinized，and the diagnostic process，differential diagnoses，and preventive strategies are deliberated to provide clinical practitioners with insights into effective management strategies.