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中华口腔医学研究杂志(电子版) ›› 2025, Vol. 19 ›› Issue (01) : 9 -15. doi: 10.3877/cma.j.issn.1674-1366.2025.01.002

牙颌面畸形专栏·中青年专家笔谈

牵张成骨在牙颌面畸形治疗中的应用
林宥宏1, 李运峰1,()   
  1. 1.口腔疾病防治全国重点实验室,国家口腔医学中心,国家口腔疾病临床医学研究中心,四川大学华西口腔医院正颌及关节外科,成都 610041
  • 收稿日期:2024-11-05 出版日期:2025-02-01
  • 通信作者: 李运峰
  • 基金资助:
    国家自然科学基金(81300858)

Application of distraction osteogenesis in the treatment of dentofacial deformities

Youhong Lin1, Yunfeng Li1,()   

  1. 1.State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthognathic & TMJ Surgery,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China
  • Received:2024-11-05 Published:2025-02-01
  • Corresponding author: Yunfeng Li
引用本文:

林宥宏, 李运峰. 牵张成骨在牙颌面畸形治疗中的应用[J/OL]. 中华口腔医学研究杂志(电子版), 2025, 19(01): 9-15.

Youhong Lin, Yunfeng Li. Application of distraction osteogenesis in the treatment of dentofacial deformities[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2025, 19(01): 9-15.

牵张成骨是苏联矫形外科医生伊里扎洛夫在“二战”期间偶然发现的。牵张成骨被发现后的几十年中,并没有在颌面外科获得有效应用。直到1992年,美国的McCarthy 医生才首次利用牵张成骨治疗半侧颜面短小畸形,开创了牵张成骨在颌面外科应用的先例。从此,牵张成骨被发扬光大,在颌面外科领域获得了广泛的应用。牵张成骨是一种内源性骨增量技术,在颌面外科领域主要用于颌骨缺损、颌骨发育不足的治疗。从发展历史可以看出,牵张成骨并不是天然属于正颌外科范畴,但由于其与牙颌面畸形的密切关系,正颌外科医师最早使用并掌握了牵张成骨技术。作为常规正颌手术的重要补充,牵张成骨技术成为正颌外科医师的重要工具,牵张成骨的教学任务也大多是正颌外科医师承担的。本文以作者的临床经验、临床病例为基础,结合当前国内外最新文献,重点介绍牵张成骨在牙颌面畸形治疗中的应用。

Distraction osteogenesis (DO) was accidentally discovered by the Soviet orthopedic surgeon,Ilizarov,during World War Ⅱ.In the decades following its discovery,DO was not effectively applied in maxillofacial surgery until 1992,when Dr.McCarthy from the United States firstly used DO to treat hemifacial microsomia,setting a precedent for the application of DO in maxillofacial surgery.Since then,DO has been further developed and widely applied in the field of maxillofacial surgery.DO is an autologous bone augmentation technique that is mainly used in maxillofacial surgery to treat jaw defects and insufficient jaw development.It can be seen from the history of its development that DO was not originally part of orthognathic surgery.However,due to its close relationship with dentofacial deformities,orthognathic surgeons were the first to learn and master DO.As a complement to conventional orthognathic surgery, DO has become an important tool for orthognathic surgeons,such that its teaching is also mostly undertaken by orthognathic surgeons.Based on the authors' clinical experience and cases,and in combination with the latest domestic and international literature,this article focuses on the application of DO in the treatment of dentofacial deformities.

图1 半侧颜面短小患儿治疗前影像资料 A:正面相;B:侧面相;C:三维CT正面观;D:三维CT侧面观;主要表现为患侧下颌升支和下颌体短小,下颌骨整体向患侧倾斜,此病例软组织症状较轻,没有外耳畸形。
图2 半侧颜面短小患儿接受牵张成骨治疗,牵张期结束后的影像资料 A:正面相;B:侧面相;C:三维CT正面观;D:三维CT侧面观;可见患侧下颌短小得到矫正,必要时可适度过矫正,以弥补后期患侧下颌的发育不足。
图3 唇腭裂术后继发严重上颌后缩患者牵张成骨治疗过程影像资料 A:治疗前侧面相;B:治疗中侧面相;C:治疗后侧面相;D:治疗前头颅侧位片;E:治疗中头颅侧位片;F:治疗后头颅侧位片。
图4 唇腭裂术后继发严重上颌后缩患者行上颌牵张成骨治疗的手术过程口内相 A:行上颌骨LefortⅠ型骨切开术;B:在上颌骨前壁放置小型钛板,用于连接钢丝和颅颌支架式牵张器。
图5 严重上颌牙弓狭窄患者治疗前影像 A:正面相;B:正面咬合相,可见上颌牙弓狭窄,与下颌牙弓宽度不匹配。
图6 严重上颌牙弓狭窄患者行外科辅助快速扩弓治疗的手术过程口内相 A:行上颌骨LefortⅠ型骨切开术、离断翼上颌连接、离断鼻中隔和腭中缝;B:放置正畸治疗专用扩弓器。
图7 严重上颌牙弓狭窄患者行外科辅助快速扩弓治疗前后的牙弓情况 A:扩弓前;B:扩弓后;可见治疗后上颌牙弓宽度显著增大。
图8 单侧关节强直患者治疗前影像资料 A:正面相;B:张口相;C:侧面相;D:三维CT正面观;E:三维CT侧面观;F:冠状面CT断层图像;患者表现为张口受限,单侧关节融合、升支及下颌体短小以及咬合平面偏斜。
图9 单侧关节强直患者接受关节成形和牵张成骨治疗后的影像资料 A:正面相;B:张口相;C:侧面相;D:三维CT正面观;E:三维CT侧面观;F:取掉牵张器并行颏成形后的三维CT侧面观;可见治疗后患者张口度恢复正常,面部外形获得改善。
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