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中华口腔医学研究杂志(电子版) ›› 2024, Vol. 18 ›› Issue (04) : 257 -261. doi: 10.3877/cma.j.issn.1674-1366.2024.04.007

综述

根尖生物膜清除方法的研究进展
卢铭浩1, 李红2,†(), 侯本祥1   
  1. 1. 首都医科大学附属北京口腔医院口腔显微诊疗中心，北京　100050
    2. 首都医科大学附属北京口腔医院牙体牙髓科，北京　100050
  • 收稿日期:2024-05-05 出版日期:2024-08-01
  • 通信作者: 李红

Research progress of periapical biofilm removal methods

Minghao Lu1, Hong Li2,†(), Benxiang Hou1   

  1. 1. Department of Dental Microscopy Center, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China
    2. Department of Endodontics, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China
  • Received:2024-05-05 Published:2024-08-01
  • Corresponding author: Hong Li
  • Supported by:
    Beijing Municipal Administration of Hospitals Incubating Program(PX2023055); Innovation Foundation of Beijing Stomatological Hospital of Capital Medical University(23-09-20)
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卢铭浩, 李红, 侯本祥. 根尖生物膜清除方法的研究进展[J]. 中华口腔医学研究杂志(电子版), 2024, 18(04): 257-261.

Minghao Lu, Hong Li, Benxiang Hou. Research progress of periapical biofilm removal methods[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2024, 18(04): 257-261.

根尖生物膜是指存在于感染根管牙根表面牙骨质上的生物膜，常见于难治性根尖周炎或持续性根尖周炎，可导致根尖周病变迁延不愈。因其存在位置隐匿且附着牢固，难以清除干净，给感染控制带来了巨大挑战。如何有效清除根尖生物膜是临床关注的重点和热点问题。本文就清除根尖生物膜方法的基础和临床研究进展作一综述。

关键词: 根尖生物膜, 根外生物膜, 根尖手术, 根外感染, 慢性根尖周炎

Periapical biofilm refers to the biofilm that exists on the cementum of the root surface of infected root canals. It is commonly found in refractory periapical periodontitis or persistent periapical periodontitis, which leads to the non-healing of periapical periodontitis. Because of its special location and firm attachment to apical surface, it is difficult to clear up and has brought great challenges to infection control. How to effectively remove the periapical biofilm is the focus and hot issue of clinical attention. This review highlighted the basic and clinical research of the methods of removing periapical biofilm in recent years.

Key words: Periapical biofilm, Extraradicular biofilm, Endodontic surgery, Extraradicular infection, Chronic periapical periodontitis
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