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中华口腔医学研究杂志(电子版) ›› 2019, Vol. 13 ›› Issue (01) : 13 -18. doi: 10.3877/cma.j.issn.1674-1366.2019.01.003

所属专题: 文献

基础研究

保留颊侧部分牙根对牙槽窝改建影响的动物研究
邓衍铭1, 董豫1, 许若谷1, 胡修城1, 邓飞龙1,()   
  1. 1. 中山大学光华口腔医学院·附属口腔医院,广东省口腔医学重点实验室,广州 510055
  • 收稿日期:2018-09-12 出版日期:2019-02-01
  • 通信作者: 邓飞龙

The influence of buccal partial root on socket alteration: an animal study

Yanming Deng1, Yu Dong1, Ruogu Xu1, Xiucheng Hu1, Feilong Deng1,()   

  1. 1. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2018-09-12 Published:2019-02-01
  • Corresponding author: Feilong Deng
  • About author:
    Corresponding author: Deng Feilong, Email:
  • Supported by:
    Science and Technology Major Project of Guangdong Province(2017B090912004)
引用本文:

邓衍铭, 董豫, 许若谷, 胡修城, 邓飞龙. 保留颊侧部分牙根对牙槽窝改建影响的动物研究[J]. 中华口腔医学研究杂志(电子版), 2019, 13(01): 13-18.

Yanming Deng, Yu Dong, Ruogu Xu, Xiucheng Hu, Feilong Deng. The influence of buccal partial root on socket alteration: an animal study[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2019, 13(01): 13-18.

目的

研究牙槽窝内保留颊侧部分牙根,对牙槽窝颊侧骨板高度及牙槽窝骨愈合速度的影响。

方法

选择4只成年Beagle犬双侧下颌及第二、三、四前磨牙的远中根作为实验位点。采用平行对照随机分为以下3组:(1)血液充盈组:拔除前磨牙远中根,血液充盈后关闭创口;(2)Bio-Oss Collagen组:拔除前磨牙远中根,牙槽窝内植入Bio-Oss Collagen,牙槽窝表面覆盖Bio-Gide,严密关闭创口;(3)部分牙根+血液充盈组:去除前磨牙远中根牙冠及牙根的舌侧部分,保留颊侧部分牙根,血液充盈牙槽窝后关闭创口。术后12周拍摄Beagle犬下颌锥形束CT(CBCT),比较颊侧骨板高度变化以及牙槽窝内的成骨情况。采用SPSS 21.0统计软件对颊侧骨板高度吸收量进行秩和检验,检验水准α = 0.05。

结果

术后12周,血液充盈组颊侧骨板高度降低(1.63 ± 0.67)mm,Bio-Oss Collagen组颊侧骨板高度降低(0.77 ± 0.58)mm,部分牙根+血液充盈组颊侧骨板高度降低(0.06 ± 0.10)mm。Bio-Oss Collagen组牙槽窝颊侧骨板吸收量小于血液充盈组,差异具有统计学意义(Z=-2.205,P = 0.027),部分牙根+血液充盈组颊侧骨板吸收量小于血液充盈组,差异具有统计学意义(Z=-3.361,P= 0.001),部分牙根+血液充盈组颊侧骨板吸收量小于Bio-Oss Collagen组,差异具有统计学意义(Z=-2.260,P= 0.024)。术后12周血液充盈组牙槽窝中间区域显示低密影,Bio-Oss Collagen组牙槽窝高密影,形态与牙根轮廓相似,部分牙根+血液充盈组可见较多地松质骨影像。

结论

牙槽窝内保留颊侧部分牙根,相比牙槽窝内植入Bio-Oss Collagen,能更好地保存颊侧骨板高度。保留颊侧部分牙根具有促进牙槽窝内骨生成,加快牙槽窝骨愈合速度的作用。

Objective

To observe the buccal bone plate height and socket alteration with a buccal partial root in a tooth socket.

Methods

Four adult male Beagle dogs were used. Bilateral mandible the 2nd to 4th premolar distal roots were randomly divided into three groups, i.e., the group of blood filling (the root was extracted and the wound was sutured after blood filling) , the group of Bio-Oss Collagen (the root was extracted and the wound was filled with Bio-Oss Collagen and covered with Bio-Gide before suturing) and the group of buccal partial root combined with blood filling (the lingual partial root was removed while the buccal partial root was kept; the wound was sutured after blood filling) . CBCT analysis was carried out on the first day and 12th week post operation. Vertical buccal bone plate alteration and osteogenesis effect in sockets were observed with the 12th week CBCT images. Statistical analysis was carried out with SPSS 21.0 and the significance level was 0.05.

Results

The buccal bone plate height in the group of blood filling reduced (1.63 ± 0.67) mm, while that of the group of Bio-Oss Collagen and the group of buccal partial root combined with blood filling was (0.77 ± 0.58) mm and (0.06 ± 0.10) mm, respectively. The vertical height alteration of buccal bone plate was much less in the group of Bio-Oss Collagen than the group of blood filling (Z=-2.205, P= 0.027) . So was the group of buccal partial root combined with blood filling compared with the group of blood filling (Z=-3.361, P= 0.001) and the group of buccal partial root combined with blood filling compared with the group of Bio-Oss Collagen (Z=-2.260, P= 0.024) . The sockets were comparatively empty in the group of blood filling. High density bone graft substitute was observed in the group of Bio-Oss Collagen. Cancellous bone was observed in the group of buccal partial root combined with blood filling.

Conclusions

A buccal partial root resided in the tooth socket seems have a better ability to maintain the height of the buccal bone plate than Bio-Oss Collagen. A buccal partial root may accelerate new bone formation and be in favor of tooth socket healing.

表1 不同处理方法12周后Beagle犬牙槽窝颊侧骨板高度的变化( ± s,mm)
图1 血液充盈组牙槽窝骨愈合的锥形束CT图像 A:冠状面;B:矢状面(层厚:2 mm)
图2 Bio-Oss Collagen组牙槽窝骨愈合的锥形束CT图像 A:冠状面;B:矢状面(层厚:2 mm)
图3 部分牙根+血液充盈组牙槽窝骨愈合的锥形束CT图像 A:冠状面;B:矢状面(层厚:2 mm)
[1]
Araújo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog[J]. J Clin Periodontol,2005,32(2):212-218. DOI:10.1111/j.1600-051X.2005.00642.x.
[2]
Schropp L, Wenzel A, Kostopoulos L,et al. Bone healing and soft tissue contour changes following single-tooth extraction:a clinical and radiographic 12-month prospective study[J]. Int J Periodontics Restorative Dent,2003,23(4):313-323. DOI:10.1054/ijom.2002.0384.
[3]
Araújo MG, Silva CO, Misawa M,et al. Alveolar socket healing:what can we learn?[J]. Periodontology 2000,2015,68(1):122-134. DOI:10.1111/prd.12082.
[4]
Sharma A, Oberoi SS, Saxena S. Submergence of vital roots for the preservation of residual ridge:a clinical study[J]. Oral Health Prev Dent,2012,10(3):259-265. DOI:10.4047/jap.2012.4.4.259.
[5]
Salama M, Ishikawa T, Salama H,et al. Advantages of the root submergence technique for pontic site development in esthetic implant therapy[J]. Int J Periodontics Restorative Dent,2007,27(6):521-527.
[6]
Wong KM, Chneh CM, Ang CW. Modified root submergence technique for multiple implant-supported maxillary anterior restorations in a patient with thin gingival biotype:a clinical report[J]. J Prosthet Dent,2012,107(6):349-352. DOI:10.1016/S0022-3913(12)00071-6.
[7]
Araújo MG, Sukekava F, Wennström JL,et al. Ridge alterations following implant placement in fresh extraction sockets:an experimental study in the dog[J]. J Clin Periodontol,2005,32(6):645-652. DOI:10.1111/j.1600-051X.2005.00726.x.
[8]
Hürzeler MB, Zuhr O, Schupbach P,et al. The socket-shield technique:a proof-of-principle report[J]. J Clin Periodontol,2010,37(9):855-862. DOI:10.1111/j.1600-051X.2010.01595.x.
[9]
Cherel F, Etienne D. Papilla preservation between two implants:a modified socket-shield technique to maintain the scalloped anatomy?A case report[J]. Quintessence Int,2014,45(1):23-30. DOI:10.3290/j.qi.a30765.
[10]
Barone A, Aldini NN, Fini M,et al. Xenograft versus extraction alone for ridge preservation after tooth removal:a clinical and histomorphometric study[J]. J Periodontol,2008,79(8):1370-1377. DOI:10.1902/jop.2008.070628.
[11]
Araújo MG, da Silva JCC, de Mendonça AF,et al. Ridge alterations following grafting of fresh extraction sockets in man. A randomized clinical trial[J]. Clin Oral Implants Res,2015,26(4):407-412. DOI:10.1111/clr.12366.
[12]
Bäumer D, Zuhr O, Rebele S,et al. The socket-shield technique:first histological,clinical,and volumetrical observations after separation of the buccal tooth segment - a pilot study[J]. Clin Implant Dent Relat Res,2015,17(1):71-82. DOI:10.1111/cid.12076.
[13]
Araújo M, Linder E, Lindhe J. Effect of a xenograft on early bone formation in extraction sockets:an experimental study in dog[J]. Clin Oral Implants Res,2009,20(1):1-6. DOI:10.1111/j.1600-0501.2008.01606.x.
[14]
Antunes AA, Oliveira Neto P, de Santis E,et al. Comparisons between Bio-Oss® and Straumann® Bone Ceramic in immediate and staged implant placement in dogs mandible bone defects[J]. Clin Oral Implants Res,2013,24(2):135-142. DOI:10.1111/j.1600-0501.2011.02385.x.
[15]
Tsukiboshi M, Tsukiboshi T. Bone morphology after delayed tooth replantation - case series[J]. Dent Traumatol,2014,30(6):477-483. DOI:10.1111/edt.12111.
[16]
Kan JY, Rungcharassaeng K. Proximal socket shield for interimplant papilla preservation in the esthetic zone[J]. Int J Periodontics Restorative Dent,2013,33(1):e24-e31. DOI:10.11607/prd.1346.
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