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中华口腔医学研究杂志(电子版) ›› 2016, Vol. 10 ›› Issue (06) : 421 -424. doi: 10.3877/cma.j.issn.1674-1366.2016.06.010

所属专题: 口腔医学 文献

综述

乳牙牙髓干细胞的研究进展
李思洁1, 赵玮1,()   
  1. 1. 510055 广州,中山大学光华口腔医学院·附属口腔医院,广东省口腔医学重点实验室
  • 收稿日期:2016-10-09 出版日期:2016-12-01
  • 通信作者: 赵玮
  • 基金资助:
    国家自然科学基金(81472526); 广东省自然科学基金(2014A030313126); 广州市科技计划(201609010015)

Research progress on the stem cells isolated from exfoliated deciduous teeth

Sijie Li1, Wei Zhao1,()   

  1. 1. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2016-10-09 Published:2016-12-01
  • Corresponding author: Wei Zhao
  • About author:
    Corresponding author: Zhao Wei, Email:
引用本文:

李思洁, 赵玮. 乳牙牙髓干细胞的研究进展[J/OL]. 中华口腔医学研究杂志(电子版), 2016, 10(06): 421-424.

Sijie Li, Wei Zhao. Research progress on the stem cells isolated from exfoliated deciduous teeth[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2016, 10(06): 421-424.

乳牙牙髓干细胞(SHED)来源于脱落的乳牙牙髓,具有较强的增殖能力、自我更新能力、多向分化潜能,而且乳牙为生物废弃物,符合伦理要求,所以渐渐成为干细胞领域研究的新热点。本文就SHED的生物学特征、培养方法、鉴定方法、多向分化潜能及其在疾病治疗中应用的研究进展作一综述。

Stem cells from human exfoliated deciduous teeth (SHED) mainly come from exfoliated deciduous teeth. They possess the properties of high proliferation, self-renewal and multiple differentiations potential. Furthermore, deciduous teeth, a biological disposal of waste, conform to ethical concerns. Therefore, SHED gradually become a focus in stem cell research. This review highlights recent advance of the biology characteristic, culture methods, identification methods, multiple differentiation potential of SHED and the application of SHED in the treatment.

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