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中华口腔医学研究杂志(电子版) ›› 2015, Vol. 09 ›› Issue (01) : 63 -68. doi: 10.3877/cma.j.issn.1674-1366.2015.01.010

所属专题: 文献

临床研究

终末期肾脏病患者鼻测口臭相关影响因素的Logistic回归分析
赵颖1, 孙玉华2, 冯锦红3, 韩建国4,()   
  1. 1. 221002 徐州医学院附属医院口腔科
    2. 221002 徐州医学院附属医院口腔科;221004 徐州医学院口腔医学院
    3. 221002 徐州医学院附属医院肾内科
    4. 221004 徐州医学院口腔医学院
  • 收稿日期:2014-10-05 出版日期:2015-02-01
  • 通信作者: 韩建国
  • 基金资助:
    江苏省自然科学基金(青年科技人才专项资金,BK20141141)

Analysis of the influence factors and clinical indices for halitosis in end-stage renal disease patients through multiple logistic regression

Ying Zhao1, Yuhua Sun2, Jinhong Feng3, Jianguo Han4,()   

  1. 1. Department of Stomatology, Affiliated Hospital of Xuzhou Medical College, Xuzhou 221002, China
    2. Department of Stomatology, Affiliated Hospital of Xuzhou Medical College, Xuzhou 221002, China; School of Stomatology, Xuzhou Medical College, Xuzhou 221004, China
    3. Renal Department of Internal Medicine, Affiliated Hospital of Xuzhou Medical College, Xuzhou 221002, China
    4. School of Stomatology, Xuzhou Medical College, Xuzhou 221004, China
  • Received:2014-10-05 Published:2015-02-01
  • Corresponding author: Jianguo Han
  • About author:
    Corresponding author: Han Jianguo, Email:
引用本文:

赵颖, 孙玉华, 冯锦红, 韩建国. 终末期肾脏病患者鼻测口臭相关影响因素的Logistic回归分析[J]. 中华口腔医学研究杂志(电子版), 2015, 09(01): 63-68.

Ying Zhao, Yuhua Sun, Jinhong Feng, Jianguo Han. Analysis of the influence factors and clinical indices for halitosis in end-stage renal disease patients through multiple logistic regression[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2015, 09(01): 63-68.

目的

探讨终末期肾脏病(ESRD)患者口臭与相关影响因素的关系。

方法

分别用茚三酮分光光度法和鼻测法检测ESRD患者口气中氨的浓度值和感官口气值(OS),并统计性别、年龄、学历、透析时间、抽烟史、氨值、肌酐、尿素氮、唾液pH值、舌苔面积、舌苔厚度等因素,分析鼻测法与这些检测指标之间的Logistic回归关系。

结果

在α=0.05水平,单因素Logistic回归分析显示氨值、尿素氮、舌苔厚度、唾液pH值等4个因素为ESRD患者口臭的危险因素,进一步作多因素Logistic回归分析表明,氨值是ESRD患者口臭最可能的危险因素。

结论

SRD患者体内不能完全代谢的氨是产生氨性口臭最可能的危险因素。

Objective

To study the relationship between the influence factors and halitosis in end-stage renal disease (ESRD) patients.

Methods

Organoleptic scores (OS) and concentration value of ammonia were measured independently by organoleptic assessment and ninhydrin spectrophotometry. Factors such as gender, age, education, duration of dialysis, smoking history, ammonia, urea nitrogen, creatinine, salivary pH, area and thickness of tongue coating were statistically analyzed. The Logistic regression relationship of oroganolepticscores and other clinical indices was studied.

Results

At the level of α=0.05, the single factor Logistic regression analysis showed that four factors including the ammonia, urea nitrogen, the thickness of tongue coating and salivary pH were the risk factors of halitosis in patients with end stage renal disease. Further multivariate Logistic regression analysis showed that ammonia was the most possible risk factor of halitosis in patients with end stage renal disease.

Conclusion

Ammonia not completely metabolized in the body of patients with end stage renal disease is the most possible risk factor of halitosis in these patients.

表1 鼻测法计分结果
图1 氨浓度与相应吸光度散点图
表2 终末期肾脏病患者口臭相关影响因素的单因素Logistic回归分析
表3 终末期肾脏病患者口臭相关影响因素的多因素Logistic回归分析结果
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