切换至 "中华医学电子期刊资源库"

中华口腔医学研究杂志(电子版) ›› 2013, Vol. 07 ›› Issue (02) : 161 -163. doi: 10.3877/cma.j.issn.1674-1366.2013.02.018

综述

富血小板纤维蛋白在口腔医学中的应用
郑友丽1, 张国志1,()   
  1. 1. 518020 深圳,暨南大学第二临床医学院·深圳市人民医院口腔医学中心
  • 收稿日期:2012-08-19 出版日期:2013-04-01
  • 通信作者: 张国志

The application of platelet-rich fibrin in oral medicine

You-li ZHENG1, Guo-zhi ZHANG1,()   

  1. 1. Oral Medical Center,Shenzhen People's Hospital,Second Clinical Medical College of Jinan University,Shenzhen 518020,China
  • Received:2012-08-19 Published:2013-04-01
  • Corresponding author: Guo-zhi ZHANG
引用本文:

郑友丽, 张国志. 富血小板纤维蛋白在口腔医学中的应用[J/OL]. 中华口腔医学研究杂志(电子版), 2013, 07(02): 161-163.

You-li ZHENG, Guo-zhi ZHANG. The application of platelet-rich fibrin in oral medicine[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2013, 07(02): 161-163.

富血小板纤维蛋白(PRF)是继富血小板血浆之后的第二代血小板浓缩制品,其制备简单,经济方便,且具有良好的促进软、硬组织再生的能力,在口腔医学基础和临床研究中有广泛应用。 本文结合国内外文献,对PRF 的制备方法、生物学特性及其在口腔医学中的应用作一综述。

The platelet-rich fibrin is the second-generation platelet concentrate products following the platelet-rich plasma. It has the advantage of simple preparation,economical,convenient,and it is able to promote the regeneration of soft and hard tissues. Therefore,it has been widely use in the stomatology basic and clinical research. In this paper,we reviewed the preparation methods,biological characteristics of platelet-rich fibrin and its application in oral medicine combining domestic and foreign literature.

1
Anilkumar K,Geetha A,Umasudhakar,et al. Platelet-richfibrin: A novel root coverage approach. J Indian Soc Periodontol,2009,13(1):50-54.
2
马宁,张正,金明光,等. GBR 联合PRF 修复根尖周囊肿骨缺损的临床观察. 吉林大学学报(医学版),2011,37(2):295.
3
孙洁,张剑明,李彦秋. 富血小板纤维蛋白超微结构的观察与探讨. 口腔医学研究,2010,26(1):98-101.
4
Dohan DM,Choukroun J,Diss A,et al. Platelet-rich fibrin(PRF): A second-generation platelet concentrate. PartⅢ: Leucoeyteactivation: a new feature for platelet concentrates. Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2006,101(3):e51-e55.
5
He L,Lin Y,Hu X,et al. A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2009,108(5):707-713.
6
Dohan Ehrenfest DM,Diss A,Odin G,et al. In vitro effects of Choukroun's PRF (platelet-rich fibrin) on human gingival fibroblasts,dermal prekeratinocytes,preadipocytes,and maxillofacial osteoblasts in primary cultures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2009,108(3):341-352.
7
Dohan Ehrenfest DM,Doglioli P,de Peppo GM,et al.Choukroun' s platelet-rich fibrin (PRF) stimulates in vitro proliferation and differentiation of human oral bone mesenchymal stem cell in a dose-dependent way. Arch Oral Biol,2010,55(3):185-194.
8
Huang FM,Yang SF,Zhao JH,et al. Platelet-rich fibrin increases proliferation and differentiation of human dental pulp cells. J Endod,2010,36(10):1628-1632.
9
Sharma A,Pradeep AR. Treatment of 3-wall intrabony defects in chronic periodontitis subjects with autologous platelet-rich ribrin: a randomized controlled clinical trial. J Periodontol,2011,82(12):1705-1712.
10
Sharma A,Pradeep AR. Autologous platelet rich fibrin in the treatment of mandibular degree Ⅱ furcation defects: a randomized clinical trial. J Periodontol,2011,82(10):1396-1403.
11
Nkenke E,Schlegel A,Schultze-Mosgau S,et al. The endoscopically controlled osteotome sinus floor elevation: a preliminary prospective study. Int J Oral Maxillofac Implants,2002,17(4):557-566.
12
Jang ES,Park JW,Kweon H,et al. Restoration of periimplant defects in immediate implant installations by Choukroun platelet-rich fibrin and silk fibroin powder combination graft.Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2010,109(6):831-836.
13
Choukroun J,Diss A,Simonpieri A,et al. Platelet-rich fibrin(PRF):a second-generation platelet concentrate.PartV:histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2006,101(3):299-303.
14
Inchingolo F,Tatullo M,Marrelli M,et al. Trial with Platelet-Rich Fibrin and Bio-Oss used as grafting materials in the treatment of the severe maxillar bone atrophy: clinical and radiological evaluations. Eur Rev Med Pharmacol Sci,2010,14(12):1075-1084.
15
Gürbüzer B,Pikdöken L,Tunali M,et al. Scintigraphic evaluation of osteoblastic activity in extraction sockets treated with platelet-rich fibrin. J Oral Maxillofac Surg,2010,68(5):980-989.
[1] 李雪, 韩萌萌, 冯雪园, 马宁. 人表皮生长因子受体2低表达乳腺癌的研究进展及挑战[J/OL]. 中华普通外科学文献(电子版), 2024, 18(04): 308-312.
[2] 杨培容, 潘刚, 周春霞. 胰腺癌术后胰瘘的危险因素及治疗进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 228-230.
[3] 姚宏伟, 孙丽婷, 吴偲, 舒文龙, 高加勒, 杨正阳, 吴国聪, 张忠涛. 新辅助放化疗联合免疫治疗局部进展期直肠癌的探索与实践[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 123-127.
[4] 王乾宇, 杜峻峰, 李世拥. 新辅助放化疗联合免疫治疗局部进展期直肠癌的突破与挑战[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 128-131.
[5] 邓崇文, 廖喜望, 施幼雄, 龚俊, 钟洪. 腹腔镜下胃癌D2根治+腹主动脉旁淋巴结清扫术治疗局部进展期胃癌的临床研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 180-183.
[6] 孙莲, 马红萍, 吴文英. 局部进展期甲状腺癌患者外科处理[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 112-114.
[7] 何羽. 腔镜微创手术治疗分化型甲状腺癌的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(04): 456-458.
[8] 刘璐璐, 何羽. 慢性阻塞性肺病患者睡眠障碍的研究进展[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(05): 836-839.
[9] 张瑜, 姜梦妮. 基于DWI信号值构建局部进展期胰腺癌放化疗生存获益预测模型[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(05): 657-664.
[10] 王哲学, 白峻阁, 姜得地, 李月刚, 杨明, 陈海鹏, 刘正. 局部进展期直肠癌经新辅助放化疗后肿瘤退缩分级及预后的影响因素分析[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(05): 368-374.
[11] 国文凯, 纪鹏程, 毕靖茹, 谢院生. IgA 肾病的十种治疗措施[J/OL]. 中华肾病研究电子杂志, 2024, 13(06): 327-333.
[12] 刘琦, 王守凯, 王帅, 苏雨晴, 马壮, 陈海军, 司丕蕾. 乳腺癌肿瘤内微生物组的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 841-845.
[13] 丁洪基, 赵长江, 孙鹏飞, 王灿, 王贵珍, 李龙龙. 细胞焦亡与疾病的关系研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 682-686.
[14] 黄宏山, 陈成彩. 经淋巴管超声造影在乳腺癌前哨淋巴结诊断中的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(04): 411-414.
[15] 王丽娜, 吕书霞, 李亚男. 脑卒中偏瘫患者健康焦虑元认知与疾病接受度、恐惧疾病进展的相关性[J/OL]. 中华脑血管病杂志(电子版), 2024, 18(05): 434-440.
阅读次数
全文


摘要