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中华口腔医学研究杂志(电子版) ›› 2021, Vol. 15 ›› Issue (05) : 320 -324. doi: 10.3877/cma.j.issn.1674-1366.2021.05.012

综述

精神心理因素与口腔扁平苔藓的相关性研究进展
王芳1, 刘炀1, 周明莉1, 高琪1,()   
  1. 1. 河北医科大学第二医院口腔内科,石家庄 050000
  • 收稿日期:2021-01-08 出版日期:2021-10-01
  • 通信作者: 高琪

Research progress on the relationship between mental/psychological factors and oral lichen planus

Fang Wang1, Yang Liu1, Mingli Zhou1, Qi Gao1,()   

  1. 1. Department of Stomatology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Received:2021-01-08 Published:2021-10-01
  • Corresponding author: Qi Gao
  • Supported by:
    Hebei Province Government-funded Excellent Talents Training Project in Clinical Medicine in 2019(23)
引用本文:

王芳, 刘炀, 周明莉, 高琪. 精神心理因素与口腔扁平苔藓的相关性研究进展[J]. 中华口腔医学研究杂志(电子版), 2021, 15(05): 320-324.

Fang Wang, Yang Liu, Mingli Zhou, Qi Gao. Research progress on the relationship between mental/psychological factors and oral lichen planus[J]. Chinese Journal of Stomatological Research(Electronic Edition), 2021, 15(05): 320-324.

口腔扁平苔藓(OLP)是一种口腔黏膜的慢性炎症性疾病,好发于中年女性,世界卫生组织(WHO)将其列为口腔潜在恶性疾患范畴。发病原因和发病机制尚不清楚,可能与遗传、免疫、感染、内分泌、微循环障碍、系统性疾病及口腔局部刺激等因素有关。研究表明,精神因素与OLP的发生、发展密切相关,负性生活事件作为应激源可造成神经-内分泌-免疫系统紊乱,OLP患者独特的人格特征影响其对应激源的认识、反应和接受能力。本文将对近年来有关OLP与精神因素的相关性研究做一综述。

Oral lichen planus (OLP) is a chronic inflammatory disease of oral mucosa, which usually occurs in middle-aged women. WHO lists it as oral potentially malignant disorders. The pathogenesis are not clear, which may be related to heredity, immunity, infection, endocrine, microcirculatory disorders, systemic diseases and oral local stimulation. Studies have shown that mental factors are closely related to the occurrence and development of OLP. Negative life events as stressors can cause neuroendocrine-immune system disorders. The unique personality characteristics of patients with OLP affect their understanding, response and acceptance of stressors. This article will review the studies on the relationship between oral lichen planus and mental/psychological factors in recent years.

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