中华口腔医学研究杂志(电子版) ›› 2010, Vol. 4 ›› Issue (01) : 17 -21. doi: 10.3877/cma.j.issn.1674-1366.2010.01.004 × 扫一扫
基础研究
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出版日期:
通信作者:
Tong ZHAO1, Cheng PENG1,†()
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赵彤, 彭诚. 非贵金属烤瓷冠修复患者龈沟液中白细胞介素-1β及天门冬氨酸转氨酶水平研究[J/OL]. 中华口腔医学研究杂志(电子版), 2010, 4(01): 17-21.
Tong ZHAO, Cheng PENG. Study on the IL-1β and aspartate aminotransferase level in gingival crevicular fluid of three base metal porcelain-fused-to-metal crowns[J/OL]. Chinese Journal of Stomatological Research(Electronic Edition), 2010, 4(01): 17-21.
目的
探讨3 种非贵金属烤瓷冠对局部牙周组织造成的影响，以及龈沟液（GCF）中白细胞介素-1β（IL-1β）、天门冬氨酸转氨酶（AST）水平与牙周组织健康状况的关系。
方法
选择临床接受非贵金属烤瓷冠修复患者38 例，共49 颗的上颌切牙；其中镍铬合金烤瓷冠19 颗，钛合金烤瓷冠15 颗，钴铬合金烤瓷冠15 颗。以同一患者对侧同名健康牙为对照，在烤瓷冠戴入6 个月后复诊，并对GCF 中IL-1β、AST 水平进行分析。
结果
3 组非贵金属烤瓷冠AST 水平均普遍高于对照健康牙，差异有统计学意义；镍铬合金、钛合金烤瓷组IL-1β 高于对照组，差异有统计学意义，钴铬合金烤瓷组IL-1β 差异无统计学意义。
结论
镍铬合金、钛合金烤瓷冠对牙周组织的不利影响较明显；而钴铬合金烤瓷冠对牙周组织造成的不利影响较小。
Objective
To investigate the effects of three base metal porcelain-fused-tometal （PFM） crowns on the periodontal tissue of the restored teeth， and discuss the relationship between the activity of IL-1β and AST in the gingival crevicular fluid （GCF） and the health of periodontal tissue.
Methods
49 maxillary incisors restored with based PFM crowns in 38 patients were selected for the study， including 19 Ni-Cr PFM crowns， 15 Ti-Ni-Cr PFM crowns and 15 Co-Cr PFM crowns.The contralateral homonymy natural healthy teeth served as control.The patients were followed up for 6 months after crown restoration.IL-1β and AST level in GCF were analyzed in the laboratory.
Results
In all these three PFM groups， the GCF-AST concentrations of the crowned teeth were higher than the controlled teeth， and there was a significant difference.The concentration of IL-1β in GCF in Ni-Cr PFM and Ti-Ni-Cr PFM group were significantly higher than that of the controlled group， but no significant difference was found between the Co-Cr PFM group and the controlled group.
Conclusions
Ni-Cr PFM and Ti-Ni-Cr PFM crowns have negative influence on periodontal tissue， Co-Cr PFM has few influence on periodontal tissue of the restored teeth.